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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- RA0764 - Provider product page
- Provider
- Oursmab
- Product name
- Rocatinlimab (Biosimilar Reference Antibody) (TNFRSF4)
- Antibody type
- Monoclonal
- Description
- Rocatinlimab (AMG 451/KHK4083) is a fully human IgG1 monoclonal antibody that acts as an OX40 antagonist. It targets and blocks OX40 (CD134), a co-stimulatory receptor on activated T cells. By inhibiting OX40-OX40L interaction, it reduces the activation, proliferation, and survival of pathogenic T cells, thereby dampening the immune response. It is specifically developed for the treatment of moderate-to-severe atopic dermatitis, aiming to reduce skin inflammation and pruritus.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- Rocatinlimab (Biosimilar Reference Antibody) (TNFRSF4)-RA0764-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- ELISA plate pre-coated Antigen protein, can bind Rocatinlimab (Biosimilar Reference Antibody) (TNFRSF4)-RA0764 in a linear range of 15.63¨C125 ng/mL.
