RA0764

antibody from Oursmab

Targeting: TNFRSF4 ACT35, CD134, OX40, TXGP1L

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0764

Provider

Oursmab

Product name

Rocatinlimab (Biosimilar Reference Antibody) (TNFRSF4)

Antibody type

Monoclonal

Description

Rocatinlimab (AMG 451/KHK4083) is a fully human IgG1 monoclonal antibody that acts as an OX40 antagonist. It targets and blocks OX40 (CD134), a co-stimulatory receptor on activated T cells. By inhibiting OX40-OX40L interaction, it reduces the activation, proliferation, and survival of pathogenic T cells, thereby dampening the immune response. It is specifically developed for the treatment of moderate-to-severe atopic dermatitis, aiming to reduce skin inflammation and pruritus.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.