Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 350012 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#350012, RRID:AB_10901161
- Product name
- PE/Cy7 anti-human CD134 (OX40)
- Antibody type
- Monoclonal
- Antigen
- HTLV 1-transformed HUT 102 cells
- Description
- CD134, also known as OX40 and TNFRSF14, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Infrared dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- PHA-stimulated (3 days) human peripheral blood lymphocytes were stained with CD4 FITC and OX-40 (clone Ber-ACT35) PE/Cy7 (top) or mouse IgG1, κ PE/Cy7 isotype control (bottom).
- Conjugate
- Near infrared dye