BS6886

antibody from Bioworld Technology, Inc
Targeting: GSK3B
Provider product page for BS6886
Western blot
Immunohistochemistry

Antibody data

Product number
BS6886 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GSK3ÉÇ polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GSK3ÉÇ.
Description
Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3K/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3Ï« and Ser9 of GSK-3ÉÇ. GSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus, and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GSK3B protein structure - BS6886 shown in red.