Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [472]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22104-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- GSK3B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSK3B antibody (Cat. #22104-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GSK3β as a potential regulator in AML: A pan-cancer multi-omics analysis.
AK3 as a Hypoxia-Angiogenesis-Related Prognostic Biomarker and Therapeutic Target in Clear Cell Renal Cell Carcinoma.
Isoginkgetin protects against degeneration of ALS motor neurons via regulating the GSK-3β-TFEB signaling axis.
Phenylephrine attenuates LPS-induced lung injury via Foxh1/GSK-3β/β-catenin-mediated alveolar epithelial cell differentiation in ARDS.
Insulin-like growth factor 2 alleviates metabolic inflammation and associated cognitive impairment in diet-induced obesity mice.
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling.
Glutamate decarboxylase 1 (GAD1) suppresses the progression of glioblastoma through GSK3β/β-catenin pathway.
Protein Modifications and Metabolic Alterations in the Rat Striatum Following Oil Mist Particulate Matter Exposure Revealed via Untargeted Metabolomics and Phosphoproteomics.
Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis.
Lathyrane diterpenoids with anti-renal fibrotic activity from the aboveground parts of Euphorbia wallichii.
Flutamide exacerbates hepatic insulin resistance in type 2 diabetic mice through overproduction of ROS and activation of NLRP3 signaling.
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Chloride Channel-3 promotes ferroptosis of traumatic brain injury via SGK1/GSK3β pathway.
Therapeutic effects of modified Changfa Zirong Powder on androgenetic alopecia through the Wnt/β-catenin signaling pathway.
A Molecular and Functional Investigation of the Anabolic Effect of an Essential Amino Acids' Blend Which Is Active In Vitro in Supporting Muscle Function.
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Discovery of anthraquinones as potent Notum inhibitors for treating osteoporosis by integrating biochemical, phytochemical, computational, and experimental assays.
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
Caffeine Sodium Benzoate-Induced Macrophage M1 Polarization Promotes Endothelial Progenitor Cell Dysfunction by Inducing Mitochondrial Dysfunction Via Targeting let-7a-5p/OPA1 Axis.
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
miR-24-3p promotes spinal cord injury repair in rats by inhibiting ferroptosis via targeting GSK-3β.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Esculin promotes skin wound healing in mice and regulates the Wnt/β-catenin signaling pathway.
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Ethyl Acetate Extract of Elsholtzia bodinieri Vaniot Attenuates Oxidative Stress in ALI Mice.
Melittin inhibits osteosarcoma growth in vitro and in vivo by inactivating the Wnt/β-catenin signaling pathway.
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma.
Dendrobine promotes bone formation via the canonical Wnt/β-catenin signaling pathway and prevents postmenopausal osteoporosis.
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Lacticaseibacillus rhamnosus HF01 postbiotics reprogram gut microbial tryptophan metabolism to coordinate enterohepatic barrier-insulin signaling axis.
Cytoplasmic TRIM24 promotes colorectal cancer cell proliferation by activating Wnt/β-catenin signaling.
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
Myogenic induced adipose-derived stem cells sheets combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) for stress urinary incontinence treatment.
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Hexokinase HK2 regulates the MYH9-GSK3β/β-catenin axis to promote myocardial regeneration and repair after injury.
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Mechanistic insights into the renoprotective effects of artesunate in cisplatin-induced acute kidney injury.
TBRG4 regulates ubiquitination of Beclin1 and participates in autophagy pathway to inhibit intervertebral disc degeneration.
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus.
Diosgenin activates ERα-dependent PI3K/AKT/GSK3β signaling to enhance brain-derived serotonin and alleviate postmenopausal bone loss.
TRIM36 inhibits lung fibroblast activation and pulmonary fibrosis through the degradation of phospho-AKT1.
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55-Mediated Signalling in Spinal Cord Injury.
SMOC2 promotes peritoneal metastasis of gastric cancer involving Wnt/β-catenin pathway modulation and inducing angiogenesis.
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK-3β Signaling.
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
DNA hypermethylation of PLTP mediated by DNMT3B aggravates vascular dysfunction in diabetic retinopathy via the AKT/GSK3β signaling pathway.
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Modified weiling decoction inhibited excessive autophagy via AKT/mTOR/ULK1 pathway to alleviate T2DM: Integrating network pharmacology and experimental validation.
Prognostic role and tumor-suppressive effects of CADM family members and the potential molecular mechanisms of CADM1 in neuroblastoma.
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment.
Delivery of exogenous miR-19b by Wharton's Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism.
Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway.
Blueberry Anthocyanin Extracts (BAEs) Protect Retinal and Retinal Pigment Epithelium Function from High-Glucose-Induced Apoptosis by Activating GLP-1R/Akt Signaling.
Astragaloside IV Relieves Mitochondrial Oxidative Stress Damage and Dysfunction in Diabetic Mice Endothelial Progenitor Cells by Regulating the GSK-3β/Nrf2 Axis.
GART promotes multiple myeloma malignancy via tumor stemness mediated by activating the HSP90α/CDK6/β-catenin axis.
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade.
RRP9 promotes prostate cancer metastasis and epithelial-mesenchymal transition through activation of the AKT/GSK3β/β-Catenin signaling pathway.
Bioengineered bacterial extracellular vesicles for targeted delivery of an osteoclastogenesis-inhibitory peptide to alleviate osteoporosis.
Pharmacological inhibition of Septins with Forchlorfenuron attenuates thrombus formation in experimental thrombotic mice models with modulating multiple signaling pathways in platelets.
Exploring the antitumor effect of curcumin-piperlongumine hybrid molecule (CP) on EGFR-TKI-resistant non-small cell lung cancer using network pharmacological analysis and experimental verification.
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Mitochondrial Calcium Uniporter-Mediated Regulation of the SIRT3/GSK3β/β-Catenin Signaling Pathway in Vascular Remodeling.
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Small molecule-driven LKB1 deacetylation is responsible for the inhibition of hepatic lipid response in NAFLD.
Knocking Down HN1 Blocks Helicobacter pylori-Induced Malignant Phenotypes in Gastric Mucosal Cells and Inhibits Gastric Cancer Cell Proliferation, Cytoskeleton Remodeling, and Migration.
PEGylated Nanoliposomal Doxorubicin Conjugated with Specific TREM2 Peptides for Glioma-Targeting Therapy.
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Identification and validation of an m5C-related lncRNA signature for predicting prognosis and immune response in clear cell renal cell carcinoma.
Camel milk exosomes regulate glucose metabolism by inhibiting mitochondrial complex I in hepatocytes.
Chemoresistance mechanisms to 5-Fluorouracil and reversal strategies in lung and breast cancer.
PFOA substitute GenX at a sub-cytotoxic level exhibits thyroid-disrupting effects by inhibiting the expression of thyroid transcription factor 1.
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.
Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo.
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Protective effect of Lonicerae Japonicae Flos extract against doxorubicin-induced myocardial injury in mice and the possible mechanisms.
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
TRIM47 Facilitates Osteosarcoma Progression via Destabilising FBP1 and Thus Activation of Wnt/β-Catenin Pathway.
High-efficient discovering the potent anti-Notum agents from herbal medicines for combating glucocorticoid-induced osteoporosis.
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Degraded Polysaccharides from Noni (Morinda citrifolia L.) juice Mitigate Glucose Metabolism Disorders by Regulating PI3K/AKT-Nrf2-GSK3β Signaling Pathways in HepG2 Cells.
Tumor suppressor OSR1 is modified by SUMO1 and regulates the Wnt/β-catenin signaling pathway in HCC.
hUC-MSC-derived extracellular vesicles protect lung tissue from cigarette smoke-induced injury by upregulating the METTL3-mediated m(6)A modification.
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation.
Mechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.
Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis.
Gallic Acid Alleviates Cognitive Impairment by Promoting Neurogenesis via the GSK3β-Nrf2 Signaling Pathway in an APP/PS1 Mouse Model.
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome.
IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway.
GPR168 functions as a tumor suppressor in mouse melanoma by restraining Akt signaling pathway.
SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau.
Cinobufacini enhances the therapeutic response of 5-Fluorouracil against gastric cancer by targeting cancer stem cells via AKT/GSK-3β/β-catenin signaling axis.
Epicatechin and β-Glucan from Whole Highland Barley Grain Synergistic Benefit on Attenuating Hyperglycemia via Improving Hepatic Glucose Metabolism in Diabetic C57BL/6J Mice.
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Forkhead box protein FOXK1 disrupts the circadian rhythm to promote breast tumorigenesis in response to insulin resistance.
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling.
Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling.
Investigation on the mechanism of androsta-4,6,8,14-tetraene-3,11,16-trione against acute lymphoblastic leukemia.
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments.
The miR-665/SOST Axis Regulates the Phenotypes of Bone Marrow Mesenchymal Stem Cells and Osteoporotic Symptoms in Female Mice.
Nine new nor-3,4-seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus and their hypoglycemic activity.
The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism.
Fast freezing inhibits melanin synthesis of melanocytes by modulating the Wnt/β-catenin signalling pathway.
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Nur77 inhibition of β-catenin expression mediates Hepatoblastoma progression and enhances cisplatin's therapeutic effect.
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer.
Scutellarin alleviates microglia-mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathway.
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer.
Gold Nanoparticle Delivery of Glut1 SiRNA Facilitates Glucose Starvation Therapy in Lung Cancer.
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Idebenone protects the kidneys of rats with renovascular arterial hypertension by inhibiting oxidative stress and apoptosis.
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
Baizhu shaoyao decoction restores the intestinal barrier and brain-gut axis balance to alleviate diarrhea-predominant irritable bowel syndrome via FoxO1/FoxO3a.
Effects of monochromatic light on hepatic glycogen and lipid synthesis in broilers.
MALAT1/miR-7-5p/TCF4 Axis Regulating Menstrual Blood Mesenchymal Stem Cells Improve Thin Endometrium Fertility by the Wnt Signaling Pathway.
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway.
β-carboline derivative Z86 attenuates colorectal cancer cell proliferation and migration by directly targeting PI3K.
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy.
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating β-catenin signaling via promoting GSK3β ubiquitination.
DPPA2/4 Promote the Pluripotency and Proliferation of Bovine Extended Pluripotent Stem Cells by Upregulating the PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Aloe Emodin Alleviates Radiation-Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption.
Melatonin nuclear receptors mediate monochromatic light-induced T-lymphocyte proliferation of thymus through the AKT/GSK3β/β-catenin pathway in chick.
Albiflorin inhibits osteoclastogenesis and titanium particles-induced osteolysis via inhibition of ROS accumulation and the PI3K/AKT signaling pathway.
SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 Axis.
Osteoblast-derived exosomal miR-140-3p targets ACER2 and increases the progression of prostate cancer via the AKT/mTOR pathway-mediated inhibition of autophagy.
Nur77 as a novel regulator of Paneth cell differentiation and function.
Protective effects of chlorogenic acid on the intestinal barrier of broiler chickens: an immunological stress model study.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation.
Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection.
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring.
Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Pharmacodynamic material basis and pharmacological mechanisms of Cortex Mori against diabetes mellitus.
Lycium Barbarum Polysaccharides Improves Cognitive Functions in ICV-STZ-Induced Alzheimer's Disease Mice Model by Improving the Synaptic Structural Plasticity and Regulating IRS1/PI3K/AKT Signaling Pathway.
Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway.
Multifunctional Lithium-Doped Mesoporous Nanoparticles for Effective Dentin Regeneration in vivo.
Ginsenoside Rb1 Promotes Hepatic Glycogen Synthesis to Ameliorate T2DM Through 15-PGDH/PGE(2)/EP4 Signaling Pathway.
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism.
Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/β-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer.
Exosomal miR-320e through wnt2targeted inhibition of the Wnt/β-catenin pathway allevisate cerebral small vessel disease and cognitive impairment.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Sertoli cell-derived extracellular vesicles traverse the blood-testis barrier and deliver miR-24-3p inhibitor into germ cells improving sperm mobility.
Sevoflurane anaesthesia induces cognitive impairment in young mice through sequential tau phosphorylation.
Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/β-catenin signaling pathway.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Voluntary wheel-running improved pulmonary fibrosis by reducing epithelial mesenchymal transformation.
Phenylethanoid glycosides derived from Cistanche deserticola promote neurological functions and the proliferation of neural stem cells for improving ischemic stroke.
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway.
Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification.
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Novel pathogenesis of post-traumatic stress disorder studied in transgenic mice.
Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease.
Citrus alkaline extracts improve LPS-induced pulmonary fibrosis via epithelial mesenchymal transition signals.
Nogo-B deficiency suppresses white adipogenesis by regulating β-catenin signaling.
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression.
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.
Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis.
GSK3β-driven SOX2 overexpression is a targetable vulnerability in esophageal squamous cell carcinoma.
Curcumin-Containing polyphosphazene nanodrug for Anti-Inflammation and nerve regeneration to improve functional recovery after spinal cord injury.
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Regulation of Sertoli cell function by planar cell polarity (PCP) protein Fjx1.
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Berberine protects mice against type 2 diabetes by promoting PPARγ-FGF21-GLUT2-regulated insulin sensitivity and glucose/lipid homeostasis.
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Overexpression of FSP1 Ameliorates ferroptosis via PI3K/ AKT /GSK3β pathway in PC12 cells with Oxygen-Glucose Deprivation/Reoxygenation.
Hydrogel-based miR-192 delivery inhibits the development of hepatocellular carcinoma by suppressing the GSK3β/Wnt/β-catenin pathway.
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
The 15-hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates abnormal hepatic glucose metabolism through PGE(2)-EP4 receptor-AKT signaling in a type 2 diabetes mellitus mouse model.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells.
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice.
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology.
Resveratrol Targets AKT1 to Inhibit Inflammasome Activation in Cardiomyocytes Under Acute Sympathetic Stress.
Empagliflozin Inhibits Hepatic Gluconeogenesis and Increases Glycogen Synthesis by AMPK/CREB/GSK3β Signalling Pathway.
Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer's Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.
A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair.
Pan-cancer analysis of trophinin-associated protein with potential implications in clinical significance, prognosis, and tumor microenvironment in human cancers.
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Aqueous extract of Scrophularia ningpoensis improves insulin sensitivity through AMPK-mediated inhibition of the NLRP3 inflammasome.
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
A novel O(2)- (2,4-dinitrophenyl) diazeniumdiolate inhibits hepatocellular carcinoma migration, invasion, and EMT through the Wnt/β-catenin pathway.
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β.
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state via GSK-3β pathway.
Inhibition of NLRP1-Dependent Pyroptosis Prevents Glycogen Synthase Kinase-3β Overactivation-Induced Hyperphosphorylated Tau in Rats.
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells.
Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt-β-catenin-STAT3 signaling.
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma.
Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway.
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Dok5 regulates proliferation and differentiation of osteoblast via canonical Wnt/β-catenin signaling.
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Restraint of FAM60A has a cancer-inhibiting role in pancreatic carcinoma via the effects on the Akt/GSK-3β/β-catenin signaling pathway.
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
A novel frameshift variant in the TSPAN12 gene causes autosomal dominant FEVR.
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Insulin and liraglutide attenuate brain pathology in diabetic mice by enhancing the Wnt/β-catenin signaling pathway.
Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways.
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Blue Light Alters the Composition of the Jejunal Microbiota and Promotes the Development of the Small Intestine by Reducing Oxidative Stress.
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder.
The neuroprotective mechanism of lithium after ischaemic stroke.
Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway.
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Role of TRPV1 channels on glycogen synthase kinase-3β and oxidative stress in ouabain-induced bipolar disease.
Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Functionalized gadofullerene ameliorates impaired glycolipid metabolism in type 2 diabetic mice.
FAM83A has a pro-tumor function in ovarian cancer by affecting the Akt/Wnt/β-catenin pathway.
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer.
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Periostin regulates osteogenesis of mesenchymal stem cells from ovariectomized rats through actions on the ILK/Akt/GSK-3β Axis.
Apelin/APJ-Manipulated CaMKK/AMPK/GSK3β Signaling Works as an Endogenous Counterinjury Mechanism in Promoting the Vitality of Random-Pattern Skin Flaps.
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
A Green and Blue Monochromatic Light Combination Therapy Reduces Oxidative Stress and Enhances B-Lymphocyte Proliferation through Promoting Melatonin Secretion.
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop.
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Exploring the synergistic mechanism of Gegen Qinlian Decoction on the Wnt signaling pathway using an integrated strategy of network pharmacology and RNA-seq.
Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
SHP-1 acts as a tumor suppressor by interacting with EGFR and predicts the prognosis of human breast cancer.
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Long noncoding RNA MEG3 expressed in human dental pulp regulates LPS-Induced inflammation and odontogenic differentiation in pulpitis.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer.
A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer's disease mechanisms.
Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor-dependent manner.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice.
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
IARS2 regulates proliferation, migration, and angiogenesis of human umbilical vein endothelial cells.
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3β/β-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats.
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
Akt inhibition-dependent downregulation of the Wnt/β-Catenin Signaling pathway contributes to antimony-induced neurotoxicity.
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
The dynamic expression of canonical Wnt/β-catenin signalling pathway in the pathologic process of experimental autoimmune neuritis.
Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure.
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin.
ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.
Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells.
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Amitriptyline Reduces Sepsis-Induced Brain Damage Through TrkA Signaling Pathway.
miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway.
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway.
Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity.
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro.
Mycoplasma hyorhinis infection promotes gastric cancer cell motility via β-catenin signaling.
Influence of Calcium Supplementation against Fluoride-Mediated Osteoblast Impairment in Vitro: Involvement of the Canonical Wnt/β-Catenin Signaling Pathway.
Metformin reverses the schizophrenia-like behaviors induced by MK-801 in rats.
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice.
XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/β-catenin signaling dependent way.
Pharmacological actions of neferine in the modulation of human platelet function.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis.
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells.
Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway.
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide promotes bone formation via the canonical Wnt/β-catenin signaling pathway.
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway.
Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Elevated GSK3β expression predicts good prognosis in hepatocellular carcinoma.
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis.
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells.
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats.
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
miR-195-5p is critical in REGγ-mediated regulation of wnt/β-catenin pathway in renal cell carcinoma.
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease.
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients.
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
MicroRNA-500a promotes migration and invasion in hepatocellular carcinoma by activating the Wnt/β-catenin signaling pathway.
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation.
Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway.
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3β and β-catenin.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a.
Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor.
RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Potent effects of dioscin against liver fibrosis.
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling.
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
Qiu R, Zhou Y, Song S, Wang Z
PloS one 2026;21(3):e0344994
PloS one 2026;21(3):e0344994
AK3 as a Hypoxia-Angiogenesis-Related Prognostic Biomarker and Therapeutic Target in Clear Cell Renal Cell Carcinoma.
Zhou D, Zheng M, Cui D, Guan B, Luo C
International journal of general medicine 2026;19:552108
International journal of general medicine 2026;19:552108
Isoginkgetin protects against degeneration of ALS motor neurons via regulating the GSK-3β-TFEB signaling axis.
Li A, Xiao X, Liu G, Li K, Ling Y, Deng S, Xu C, Cao SQ, Wen J, Lu G, Yang G, Fang EF, Qin D, Su H
Pharmacological research 2026 May;227:108172
Pharmacological research 2026 May;227:108172
Phenylephrine attenuates LPS-induced lung injury via Foxh1/GSK-3β/β-catenin-mediated alveolar epithelial cell differentiation in ARDS.
Zeng Z, Yin Y, Cong Z, Wei S, Wei X, Shen Z, Ge Q, Zhu X
International immunopharmacology 2026 May 15;177:116541
International immunopharmacology 2026 May 15;177:116541
Insulin-like growth factor 2 alleviates metabolic inflammation and associated cognitive impairment in diet-induced obesity mice.
Liu X, Chen L, Chen Y, Huang Y, Xiao X, Zhong X
Diabetes, obesity & metabolism 2026 Mar;28(3):1800-1816
Diabetes, obesity & metabolism 2026 Mar;28(3):1800-1816
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling.
Yu Z, Kuang J, Wan X, Liang C, Wu F, Shu Z, Liang W, Wan X, Gong J
In vitro cellular & developmental biology. Animal 2026 Mar 20;
In vitro cellular & developmental biology. Animal 2026 Mar 20;
Glutamate decarboxylase 1 (GAD1) suppresses the progression of glioblastoma through GSK3β/β-catenin pathway.
Zheng Y, Zhong Z, Zhang C, Gu J
Cell death discovery 2026 Mar 17;12(1)
Cell death discovery 2026 Mar 17;12(1)
Protein Modifications and Metabolic Alterations in the Rat Striatum Following Oil Mist Particulate Matter Exposure Revealed via Untargeted Metabolomics and Phosphoproteomics.
Nie H, Liu X, Shi Y, Liu H, Lai W, Li K, Tian L, Xi Z, Lin B
Toxics 2026 Mar 12;14(3)
Toxics 2026 Mar 12;14(3)
Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis.
Zhao J, Peng GG, Xiao D, Fu CJ, Chen HZ, Luo SJ, Wu HQ, Huang M
Journal of ethnopharmacology 2026 Mar 1;358:121011
Journal of ethnopharmacology 2026 Mar 1;358:121011
Lathyrane diterpenoids with anti-renal fibrotic activity from the aboveground parts of Euphorbia wallichii.
Ma RF, Liu KY, Pan YB, Zhang H
Phytochemistry 2026 Jul;247:114875
Phytochemistry 2026 Jul;247:114875
Flutamide exacerbates hepatic insulin resistance in type 2 diabetic mice through overproduction of ROS and activation of NLRP3 signaling.
Zhang Y, Zhang Y, Xiang Q, Fu X, Zhang Y, Tan L, Tang H, Li S, Gong D, Guo X, Zhang Y, Wang Q, Chen L, Zheng T
International immunopharmacology 2026 Jul 1;180:116683
International immunopharmacology 2026 Jul 1;180:116683
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Liu GY, Huang DP, Ge C, Li XY, Chen F, Fan JS, Tu HP
Clinical breast cancer 2026 Jan;26(1):298-305
Clinical breast cancer 2026 Jan;26(1):298-305
Chloride Channel-3 promotes ferroptosis of traumatic brain injury via SGK1/GSK3β pathway.
Nie Z, Fu H, Lu C, Tan L, Zhou J, Niu J, Liang R, Fang L, Fu Y, Zheng L, Wang B
Free radical biology & medicine 2026 Jan;242:474-484
Free radical biology & medicine 2026 Jan;242:474-484
Therapeutic effects of modified Changfa Zirong Powder on androgenetic alopecia through the Wnt/β-catenin signaling pathway.
Chen Y, Liang J, Yan M, Xu L, Jin F, Jiang M, Kołodyńska D, Lv G, Chen S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157606
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157606
A Molecular and Functional Investigation of the Anabolic Effect of an Essential Amino Acids' Blend Which Is Active In Vitro in Supporting Muscle Function.
d'Adduzio L, Fanzaga M, Musco MS, Sindaco M, D'Incecco P, Boschin G, Bollati C, Lammi C
Nutrients 2026 Jan 20;18(2)
Nutrients 2026 Jan 20;18(2)
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Zhao M, Shi J, Wei X, Tian W, Chen Y
Cytokine 2026 Feb;198:157079
Cytokine 2026 Feb;198:157079
Discovery of anthraquinones as potent Notum inhibitors for treating osteoporosis by integrating biochemical, phytochemical, computational, and experimental assays.
Guo J, Song Y, Sun M, Qian J, See D, Tian T, Song Y, Liu W, Deng H, Sun Y, Ge G, Zhao Y
Journal of pharmaceutical analysis 2026 Feb;16(2):101256
Journal of pharmaceutical analysis 2026 Feb;16(2):101256
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
Chen Y, Ding C, Ren M, Li Z, Liu S, Sun H, Yu S, Niu Q, Li X, Li B, Li L, Yang X, Sun Q
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
Caffeine Sodium Benzoate-Induced Macrophage M1 Polarization Promotes Endothelial Progenitor Cell Dysfunction by Inducing Mitochondrial Dysfunction Via Targeting let-7a-5p/OPA1 Axis.
Yu T, Yuan Y, Suo F, Guo R, Li W, Wang X, Suriguga, Zhao H, Tian L, Yang H, Yan Q, Feng L
Applied biochemistry and biotechnology 2026 Apr;198(4):2918-2940
Applied biochemistry and biotechnology 2026 Apr;198(4):2918-2940
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
Cheng W, Yang S, Lu Y, Wang Y, Tan AH
Scientific reports 2026 Apr 4;
Scientific reports 2026 Apr 4;
miR-24-3p promotes spinal cord injury repair in rats by inhibiting ferroptosis via targeting GSK-3β.
Wei D, Wang B, Gao J, Zhai T, Bai X, Zhu J, Zhang C, Shi C, Hao Q, Chen C, Zhao L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Apr 20;46(4):715-727
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Apr 20;46(4):715-727
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
Esculin promotes skin wound healing in mice and regulates the Wnt/β-catenin signaling pathway.
Xu M, Zhang M, Wu J, Wang J, Wu H, Xu X
CytoJournal 2025;22:32
CytoJournal 2025;22:32
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
Xue B, Yan L, Ye M, Gu D, Qian J, He N, Hu P, Lu F, Lu X, Liu M, Xu L, Bai J, Wang Y, Zhu G, Tang Q
International journal of biological sciences 2025;21(6):2476-2492
International journal of biological sciences 2025;21(6):2476-2492
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Zhang J, Wang X, Xiao J, Hong H, Chen J, Wu C, Xu G, Cui Z
International journal of nanomedicine 2025;20:11151-11168
International journal of nanomedicine 2025;20:11151-11168
Ethyl Acetate Extract of Elsholtzia bodinieri Vaniot Attenuates Oxidative Stress in ALI Mice.
Yin H, Hu J, Li Y, Feng Y, Li Z, Sun R, Tian L, Li Y
Journal of inflammation research 2025;18:7323-7336
Journal of inflammation research 2025;18:7323-7336
Melittin inhibits osteosarcoma growth in vitro and in vivo by inactivating the Wnt/β-catenin signaling pathway.
Wang X, Chang J, Sun X, Guo S, Li Y, Shi Q, Yang Y
Journal of Cancer 2025;16(12):3615-3628
Journal of Cancer 2025;16(12):3615-3628
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
Yuan Z, Hu J, Cai C, Liu F, Chen H, Zeng B
Frontiers in pharmacology 2025;16:1703562
Frontiers in pharmacology 2025;16:1703562
RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma.
Zang S, Ma J, Chen L, Cui D, Yu J
Frontiers in immunology 2025;16:1686597
Frontiers in immunology 2025;16:1686597
Dendrobine promotes bone formation via the canonical Wnt/β-catenin signaling pathway and prevents postmenopausal osteoporosis.
Li S, Liang P, Chen J, Zhang Y, Miao H, Wang T
Frontiers in pharmacology 2025;16:1616070
Frontiers in pharmacology 2025;16:1616070
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
Zhou Y, Jian S, Lu L, Li X, Qiu R
Frontiers in oncology 2025;15:1657508
Frontiers in oncology 2025;15:1657508
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Peng M, Zhang X, Yang L, Liu B
Frontiers in oncology 2025;15:1585057
Frontiers in oncology 2025;15:1585057
Lacticaseibacillus rhamnosus HF01 postbiotics reprogram gut microbial tryptophan metabolism to coordinate enterohepatic barrier-insulin signaling axis.
Sun Y, Liu X, Zhao L, Li D, Guan K, Ma Y, Wang R, Li Q
Current research in food science 2025;11:101111
Current research in food science 2025;11:101111
Cytoplasmic TRIM24 promotes colorectal cancer cell proliferation by activating Wnt/β-catenin signaling.
Wang Y, Yao Y, Liu Z, Long S, Yi F, Fang Q, Wu D, Zhu Q, Zai H, Xiao S, Wan F, Fu K
Nature communications 2025 Sep 29;16(1):8598
Nature communications 2025 Sep 29;16(1):8598
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
Shi Y, Zhao Z, Zhou S, Zhou Z, Huang Z, Zhou Z, Zhang C
Cancer letters 2025 Sep 28;628:217813
Cancer letters 2025 Sep 28;628:217813
Myogenic induced adipose-derived stem cells sheets combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) for stress urinary incontinence treatment.
Liu M, Li Y, Zhao Y, Sun F, Lu Y, Wu J, Zou Q
Journal of molecular histology 2025 Sep 10;56(5):306
Journal of molecular histology 2025 Sep 10;56(5):306
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Feng J, Miao H, Xiao Z, Xu L, Wang Y, Cao X, Wang J, Wu Z, Xia P, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Hexokinase HK2 regulates the MYH9-GSK3β/β-catenin axis to promote myocardial regeneration and repair after injury.
Zhang L, Zhang H, Ni J, Wu R, Feng Z, Wang Z, Qian L
European journal of pharmacology 2025 Oct 15;1005:178087
European journal of pharmacology 2025 Oct 15;1005:178087
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Wu C, Zhou Y, Mu Y, Cheng Y, Xu W, Huang M, Xu J, Li M, Gu J, Meng X, Qian D
Cancer cell international 2025 Oct 10;25(1):348
Cancer cell international 2025 Oct 10;25(1):348
Mechanistic insights into the renoprotective effects of artesunate in cisplatin-induced acute kidney injury.
Chen H, Guo R, Zhang C, Zhang L, Hu H, Du P, Duan J, Chen L, Ma X, Xue J, Mao Y, Jiang T
Life sciences 2025 Oct 1;378:123820
Life sciences 2025 Oct 1;378:123820
TBRG4 regulates ubiquitination of Beclin1 and participates in autophagy pathway to inhibit intervertebral disc degeneration.
Cui X, Zhang F, Cui D, Zhang W, Wu H, Chen X, Yu H
The spine journal : official journal of the North American Spine Society 2025 Nov;25(11):2569-2584
The spine journal : official journal of the North American Spine Society 2025 Nov;25(11):2569-2584
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus.
Lyu D, Xiao H, Shao Z, Li S, Li M, Pan L, Li Z, Huang H
Biochemical pharmacology 2025 Nov;241:117132
Biochemical pharmacology 2025 Nov;241:117132
Diosgenin activates ERα-dependent PI3K/AKT/GSK3β signaling to enhance brain-derived serotonin and alleviate postmenopausal bone loss.
Chen X, Zhang M, Qian L, Guo Y, Zhu Y, Taxi W, Liu M, Wang K, Song L, Zhang C, Zhang Y, Wang L, Ma Y, Hu Y
Journal of advanced research 2025 Nov 24;
Journal of advanced research 2025 Nov 24;
TRIM36 inhibits lung fibroblast activation and pulmonary fibrosis through the degradation of phospho-AKT1.
Li Y, Yang Y, Wang Y, Shi F, Zhang Y, Wen H, Pan X, Xia C, Li Z, Cui K, Zhao G, Liu H, Wang Q, Wang L, Yu G
iScience 2025 Nov 21;28(11):113775
iScience 2025 Nov 21;28(11):113775
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
Wang Z, Huang C, Liu S, Xiao P, Lu Z, Xu Y, Tian Y
Communications biology 2025 Nov 17;8(1):1590
Communications biology 2025 Nov 17;8(1):1590
LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55-Mediated Signalling in Spinal Cord Injury.
Chen D, Liu S, Tu LY, Yang MM, Xu CW, Jiang Y, Yang H, Tai CX, Wang YN, Xie YY, Shen PP, Wang B
Cell proliferation 2025 Nov 16;:e70146
Cell proliferation 2025 Nov 16;:e70146
SMOC2 promotes peritoneal metastasis of gastric cancer involving Wnt/β-catenin pathway modulation and inducing angiogenesis.
Li C, Yin L, Zhao D, Jiang Y, Li X, Yin Q, Xu J, Huang Y, Ni J, Ying J
Clinical and experimental medicine 2025 Nov 11;25(1):372
Clinical and experimental medicine 2025 Nov 11;25(1):372
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
Yan Y, Peng J, He W, Chen Y, Ye W, Yin Z, Cao Y
Life sciences 2025 Nov 1;380:123939
Life sciences 2025 Nov 1;380:123939
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Wu C, Gao Y, Jin Z, Huang Z, Wang H, Lu S, Guo S, Zhang F, Zhang J, Huang J, Tao X, Liu X, Zhang X, You L, Li Q, Wu J
Pharmacological research 2025 May;215:107743
Pharmacological research 2025 May;215:107743
Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK-3β Signaling.
Shu S, Fang J, Zhao L, Han J, Zhang M, Huang C, Cheng XW, Li S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70650
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70650
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
Wang JM, Zhang FH, Xie HY, Liu ZX, Tang YJ, Shu X, Wu YQ, Lu DH, Sun JZ, Ying YF, Ma XY, Zheng XY, Wang X, Liu B, Li JF, Xie LP, Luo JD
Cell reports 2025 May 27;44(5):115595
Cell reports 2025 May 27;44(5):115595
DNA hypermethylation of PLTP mediated by DNMT3B aggravates vascular dysfunction in diabetic retinopathy via the AKT/GSK3β signaling pathway.
Cai C, Gu C, Meng C, Wang Y, Wei Q, He S, Lai D, Wang X, Wang T, Qiu Q
Clinical epigenetics 2025 May 17;17(1):82
Clinical epigenetics 2025 May 17;17(1):82
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Dong R, Li M, Gu XF, Gao H, Wei Z, Qi H, Zhang J, Feng Q
Journal of translational medicine 2025 May 14;23(1):540
Journal of translational medicine 2025 May 14;23(1):540
Modified weiling decoction inhibited excessive autophagy via AKT/mTOR/ULK1 pathway to alleviate T2DM: Integrating network pharmacology and experimental validation.
Gao W, Wang M, Xu W, Ma R, Wang X, Sun T, Li P, Li F, He Y, Xie X, Pang X, Zhou Y, Pang G
Journal of ethnopharmacology 2025 May 12;347:119753
Journal of ethnopharmacology 2025 May 12;347:119753
Prognostic role and tumor-suppressive effects of CADM family members and the potential molecular mechanisms of CADM1 in neuroblastoma.
Wang Y, Zheng L, Liu J, Zhang M, Kan Y, Wang W, Yang J
Discover oncology 2025 May 1;16(1):648
Discover oncology 2025 May 1;16(1):648
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment.
Cheng Y, Du Y, Hu Y, Wang X, Li Q, Yan X, Dou M, Jia W, Yu F, Ba Y, Zhou G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115267
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115267
Delivery of exogenous miR-19b by Wharton's Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism.
Wu X, Wu X, Wang Z, Tian X, Zhang C, Cao G, Gu Y, Yan T
Drug delivery and translational research 2025 Mar;15(3):925-938
Drug delivery and translational research 2025 Mar;15(3):925-938
Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway.
Hong M, Zhu H, Liu W, Zhang P, Yu S, Gao Q, Shen G, Li B, Wang G
Translational cancer research 2025 Mar 30;14(3):1638-1650
Translational cancer research 2025 Mar 30;14(3):1638-1650
Blueberry Anthocyanin Extracts (BAEs) Protect Retinal and Retinal Pigment Epithelium Function from High-Glucose-Induced Apoptosis by Activating GLP-1R/Akt Signaling.
Li R, Du S, Ye Z, Yang W, Liu Y
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5886-5898
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5886-5898
Astragaloside IV Relieves Mitochondrial Oxidative Stress Damage and Dysfunction in Diabetic Mice Endothelial Progenitor Cells by Regulating the GSK-3β/Nrf2 Axis.
Zou X, Liu X, Qu W, Zhang X, Zou Y, Lin X, Hu W, Gao R, He Y, Zhou S, Huang Y, Xiong W
Applied biochemistry and biotechnology 2025 Jun;197(6):3964-3981
Applied biochemistry and biotechnology 2025 Jun;197(6):3964-3981
GART promotes multiple myeloma malignancy via tumor stemness mediated by activating the HSP90α/CDK6/β-catenin axis.
Qian J, Meng H, Wang Z, Sun Y, Xu X, Shi H, Wang C, Zhou L, Lv X, Yang Y, Gu C
European journal of pharmacology 2025 Jun 5;996:177584
European journal of pharmacology 2025 Jun 5;996:177584
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
Zhou C, Dong X, Li S, Xi Y, Liu Y, Qian X, Song Z, Zhou L, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Liu W, Xiong Y, Wang Z, Yan C, Zhang Z, Zhu H, Chen XZ, Song Z, Tang J
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade.
Zhang Y, Huang H, Zhong H, Zhang Y, He S, Guo Y, Wang Y, Huang P, Huang S, Zhong Y
Investigative ophthalmology & visual science 2025 Jun 2;66(6):8
Investigative ophthalmology & visual science 2025 Jun 2;66(6):8
RRP9 promotes prostate cancer metastasis and epithelial-mesenchymal transition through activation of the AKT/GSK3β/β-Catenin signaling pathway.
Da Z, Du Y, Chen Y, Da M, Zhou F
Discover oncology 2025 Jun 17;16(1):1129
Discover oncology 2025 Jun 17;16(1):1129
Bioengineered bacterial extracellular vesicles for targeted delivery of an osteoclastogenesis-inhibitory peptide to alleviate osteoporosis.
Kong X, Liu H, Chen S, Liu Z, Chen Q, Li X, Hu H, Su J, Shi Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113751
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113751
Pharmacological inhibition of Septins with Forchlorfenuron attenuates thrombus formation in experimental thrombotic mice models with modulating multiple signaling pathways in platelets.
Hao Z, Yan M, Tuerhong R, Zhang L, Zhang Z, Alam H, Wu J, Qin Y, Zhao F, Shi L
Journal of advanced research 2025 Jul;73:517-533
Journal of advanced research 2025 Jul;73:517-533
Exploring the antitumor effect of curcumin-piperlongumine hybrid molecule (CP) on EGFR-TKI-resistant non-small cell lung cancer using network pharmacological analysis and experimental verification.
Wang S, Lai Y, Huang H, Yuan J, Li S, Hui M, Wang P, Chen B, Liu Z, Qian J, Zhang Q
Acta biochimica et biophysica Sinica 2025 Jul 9;57(11):1803-1813
Acta biochimica et biophysica Sinica 2025 Jul 9;57(11):1803-1813
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Zeng Y, Yang Y, Zeng F, Feng Q
mSystems 2025 Jul 22;10(7):e0169224
mSystems 2025 Jul 22;10(7):e0169224
Mitochondrial Calcium Uniporter-Mediated Regulation of the SIRT3/GSK3β/β-Catenin Signaling Pathway in Vascular Remodeling.
Jiang M, Lin L, Yue S, Shi S, Yan H, Yi H, Han F, Xu S, Su J, Zhang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70761
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70761
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
Fan Y, Wu H, Yin D, Liu Q, Yuan C, Zhong T, Xia B, Xiong L, Li Y, Zeng L, Li Y, Li Y, Tang L
Bioorganic chemistry 2025 Jul 1;161:108547
Bioorganic chemistry 2025 Jul 1;161:108547
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Wei QH, Pan YB, Tian LL, Wang YS, Wang JY, Liu X, Zhang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
Zheng K, Jin G, Cao R, Gao Y, Xu J, Chai R, Kang Y
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Xu C, Li W, Mao J, Liu Z, Lao A, Mao L, Gu A, Wu J, Shen A, Lin K, Liu J
Carbohydrate polymers 2025 Jan 1;347:122787
Carbohydrate polymers 2025 Jan 1;347:122787
Small molecule-driven LKB1 deacetylation is responsible for the inhibition of hepatic lipid response in NAFLD.
Qin W, Ding Y, Zhang W, Sun L, Weng J, Zheng X, Luo S
Journal of lipid research 2025 Feb;66(2):100740
Journal of lipid research 2025 Feb;66(2):100740
Knocking Down HN1 Blocks Helicobacter pylori-Induced Malignant Phenotypes in Gastric Mucosal Cells and Inhibits Gastric Cancer Cell Proliferation, Cytoskeleton Remodeling, and Migration.
Huang Y, Wang X, Liu H, Meng X, Yin H, Hou R, Lin W, Zhang X, Ma J, Zhang X, Zhang F, Miao Y
Biochemical genetics 2025 Feb;63(1):875-895
Biochemical genetics 2025 Feb;63(1):875-895
PEGylated Nanoliposomal Doxorubicin Conjugated with Specific TREM2 Peptides for Glioma-Targeting Therapy.
Li H, Xu D, Cai W, Liu J, Bing Z, Zhang Q
Advanced healthcare materials 2025 Feb;14(4):e2403096
Advanced healthcare materials 2025 Feb;14(4):e2403096
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
Deng Z, Sun S, Zhou N, Peng Y, Cheng L, Yu X, Yuan Y, Guo M, Xu M, Cheng Y, Zhou F, Li N, Yang Y, Gu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Fan XP, Wang JR, Chen SY, Li XR, Cao JL, Wang HB, Ding LY, Che TJ, Yang L
Scientific reports 2025 Feb 8;15(1):4748
Scientific reports 2025 Feb 8;15(1):4748
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Yang W, Li Y, Tang Y, Tao Z, Yu M, Sun C, Ye Y, Xu B, Zhao X, Zhang Y, Lu X
Stem cell research & therapy 2025 Feb 28;16(1):100
Stem cell research & therapy 2025 Feb 28;16(1):100
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Wu L, Yu M, Liang H, Lin L, Li H, Chen G, Muhetaer H, Li J, Wu B, Jia X, Dang Y, Zheng G, Li C
Current issues in molecular biology 2025 Feb 27;47(3)
Current issues in molecular biology 2025 Feb 27;47(3)
Identification and validation of an m5C-related lncRNA signature for predicting prognosis and immune response in clear cell renal cell carcinoma.
Ao S, Liang L, Peng L, Yang R, Chen Z, Deng T
Discover oncology 2025 Feb 23;16(1):227
Discover oncology 2025 Feb 23;16(1):227
Camel milk exosomes regulate glucose metabolism by inhibiting mitochondrial complex I in hepatocytes.
Yang B, Du S, Liu L, Wang J, Er D
BMC veterinary research 2025 Feb 22;21(1):85
BMC veterinary research 2025 Feb 22;21(1):85
Chemoresistance mechanisms to 5-Fluorouracil and reversal strategies in lung and breast cancer.
Zhong C, Wang S, Jiang WJ, Li Z, Wang X, Fan S, Huang J, Wu HJ, Sheng R, Fei T
Scientific reports 2025 Feb 19;15(1):6074
Scientific reports 2025 Feb 19;15(1):6074
PFOA substitute GenX at a sub-cytotoxic level exhibits thyroid-disrupting effects by inhibiting the expression of thyroid transcription factor 1.
He S, Xie C, Wang Y, Wang Y, Fan C, Su S, Qian M, Yang Y
Environmental pollution (Barking, Essex : 1987) 2025 Feb 15;367:125594
Environmental pollution (Barking, Essex : 1987) 2025 Feb 15;367:125594
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
Shan J, Pu J, Chen X, Zhang Y, Li J, Qin L, Shi J, Zhou L, Deng Y
Clinical and experimental medicine 2025 Feb 1;25(1):47
Clinical and experimental medicine 2025 Feb 1;25(1):47
A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.
Zhang S, Zhao F, Pan C, Wang Y, Yang Z, Yang J, Meng Y, Lv S, Huang J, Dong L, Li L, Dong Y
Biochemical pharmacology 2025 Dec;242(Pt 2):117205
Biochemical pharmacology 2025 Dec;242(Pt 2):117205
Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo.
Li S, Zhang Y, Liu X, Su H, Cao H, Xuan H, Cui Y, Lu Z, Zhang Q, Li Y, Liu X, Bao X, Xu H, Wang Y, Zhuo X, Zhang X, Zhang Q, Zhang L
Pharmacological research 2025 Dec;222:108033
Pharmacological research 2025 Dec;222:108033
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Gao Z, Xiong Z, Tao Y, Wang Q, Guo K, Xu K, Huang H
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Protective effect of Lonicerae Japonicae Flos extract against doxorubicin-induced myocardial injury in mice and the possible mechanisms.
Xia S, Wei H, Hong W, Zhang Y, Yin F, Zhang Y, Zhang L, Gao Q, Ye H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2527-2540
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2527-2540
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
Lu W, Li Y, Liao X, Hu H, Zhang B, Liang L, Gao H
Nutrients 2025 Dec 18;17(24)
Nutrients 2025 Dec 18;17(24)
TRIM47 Facilitates Osteosarcoma Progression via Destabilising FBP1 and Thus Activation of Wnt/β-Catenin Pathway.
Wang H, Chen X, Nie F, Zhong M, Fang Z, Qiu Z, Zhou L, Le Y, Wei X, Liao Y, Fang Z
Journal of cellular and molecular medicine 2025 Aug;29(15):e70753
Journal of cellular and molecular medicine 2025 Aug;29(15):e70753
High-efficient discovering the potent anti-Notum agents from herbal medicines for combating glucocorticoid-induced osteoporosis.
Song Y, Zhang F, Guo J, Fan Y, Zeng H, Sun M, Qian J, Qi S, Chen Z, Jin X, Song Y, Tian T, Qian Z, Sun Y, Tian Z, Yu B, Ge G
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4174-4192
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4174-4192
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Tu J, Liu C, Zhang J, Li T, Zhu J, Wang Q, Wu R, Wang T
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Degraded Polysaccharides from Noni (Morinda citrifolia L.) juice Mitigate Glucose Metabolism Disorders by Regulating PI3K/AKT-Nrf2-GSK3β Signaling Pathways in HepG2 Cells.
Wei X, Du P, Luo Y, Zhao Y, Zhou X, Chen G, Zhang B
Foods (Basel, Switzerland) 2025 Aug 27;14(17)
Foods (Basel, Switzerland) 2025 Aug 27;14(17)
Tumor suppressor OSR1 is modified by SUMO1 and regulates the Wnt/β-catenin signaling pathway in HCC.
Lin X, Liu Y, Lai Z, Wang X, Cui Y, Weng S
Experimental cell research 2025 Aug 1;451(1):114693
Experimental cell research 2025 Aug 1;451(1):114693
hUC-MSC-derived extracellular vesicles protect lung tissue from cigarette smoke-induced injury by upregulating the METTL3-mediated m(6)A modification.
Wen J, Xu J, Li Y, Ma L, Wang J, Huang S, Yi X
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C426-C439
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C426-C439
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
Li F, Yu H, Zhang Y, Ma Y, Chen X, Zhang J, Sun L, Guo R, Wu Y, Zheng P, Wang X, Bie P, He F, Zhang L, Xie C, Xiong H
Nature communications 2025 Apr 30;16(1):4060
Nature communications 2025 Apr 30;16(1):4060
Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation.
Chu J, Song J, Fan Z, Zhang R, Wang Q, Yi K, Gong Q, Liu B
Pharmaceuticals (Basel, Switzerland) 2025 Apr 22;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 22;18(5)
Mechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.
Chen Q, Hu Q, Zhang F, Lu W, Yuan Z, Qiao F
Hereditas 2025 Apr 12;162(1):59
Hereditas 2025 Apr 12;162(1):59
Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis.
Chen J, Li H, Jin Q, Li X, Zhang Y, Shen J, Huang G, Yin J, Zou C, Li X, He X, Xie X, Lin T
Cellular & molecular biology letters 2025 Apr 11;30(1):45
Cellular & molecular biology letters 2025 Apr 11;30(1):45
Gallic Acid Alleviates Cognitive Impairment by Promoting Neurogenesis via the GSK3β-Nrf2 Signaling Pathway in an APP/PS1 Mouse Model.
Ding Y, He J, Kong F, Sun D, Chen W, Luo B, Wu J, Zhang S, Zhan P, Peng C
Journal of Alzheimer's disease reports 2024;8(1):461-477
Journal of Alzheimer's disease reports 2024;8(1):461-477
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome.
Wen LP, Gao SW, Chen HX, Liu Q, Xiao GZ, Lin HC, He QL
The American journal of Chinese medicine 2024;52(5):1527-1554
The American journal of Chinese medicine 2024;52(5):1527-1554
IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway.
Liu S, Li J, Zhang J, Wan F, Hong Z, Hong Z, Dai B
International journal of biological sciences 2024;20(15):6146-6161
International journal of biological sciences 2024;20(15):6146-6161
GPR168 functions as a tumor suppressor in mouse melanoma by restraining Akt signaling pathway.
Guo X, Guo Z, Bai P, Guo C, Liu X, Zhu K, Li X, Zhao Y
PloS one 2024;19(5):e0302061
PloS one 2024;19(5):e0302061
SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau.
Imai M, Kawakami F, Uematsu T, Matsumoto T, Kawashima R, Kurosaki Y, Tamaki S, Maehana S, Ichikawa T, Hanaki H, Kitazato H, Kubo M
PloS one 2024;19(10):e0312834
PloS one 2024;19(10):e0312834
Cinobufacini enhances the therapeutic response of 5-Fluorouracil against gastric cancer by targeting cancer stem cells via AKT/GSK-3β/β-catenin signaling axis.
Sun J, Zhang S, Wang M, Cheng H, Wang Y, He S, Zuo Q, Wang N, Li Q, Wang M
Translational oncology 2024 Sep;47:102054
Translational oncology 2024 Sep;47:102054
Epicatechin and β-Glucan from Whole Highland Barley Grain Synergistic Benefit on Attenuating Hyperglycemia via Improving Hepatic Glucose Metabolism in Diabetic C57BL/6J Mice.
Liu Z, Zhang Z, Tang R, Liu J, Yang Y
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20458-20469
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20458-20469
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Liu Z, Yang Y, Xu Y, Zhang Z, Tang R, Liu J, Jiang H, Zhao R
Food & function 2024 Sep 16;15(18):9272-9283
Food & function 2024 Sep 16;15(18):9272-9283
Forkhead box protein FOXK1 disrupts the circadian rhythm to promote breast tumorigenesis in response to insulin resistance.
Zhang Z, Zhao M, Wang Q, Wang X, Wang Y, Ge Y, Wu Z, Wang W, Shan L
Cancer letters 2024 Sep 1;599:217147
Cancer letters 2024 Sep 1;599:217147
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling.
Cai MN, Chen DM, Chen XR, Gu YR, Liao CH, Xiao LX, Wang JL, Lin BL, Huang YH, Lian YF
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1897-1910
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1897-1910
Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling.
Kalarikkal M, Saikia R, Oliveira L, Bhorkar Y, Lonare A, Varshney P, Dhamale P, Majumdar A, Joseph J
EMBO reports 2024 Oct;25(10):4226-4251
EMBO reports 2024 Oct;25(10):4226-4251
Investigation on the mechanism of androsta-4,6,8,14-tetraene-3,11,16-trione against acute lymphoblastic leukemia.
Chen D, Wang Y, Xiao S, Cheng G, Liu Y, Zhao T, Cao J, Wen Y
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106573
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106573
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Chang Y, Wang X, Yang J, Tien JC, Mannan R, Cruz G, Zhang Y, Vo JN, Magnuson B, Mahapatra S, Cho H, Dhanasekaran SM, Wang C, Wang Z, Zhou L, Zhou K, Zhou Y, Zhang P, Huang W, Xiao L, Liu WR, Hamadeh R, Su F, Wang R, Miner SJ, Cao X, Cheng Y, Mehra R, Ding K, Chinnaiyan AM
Cell reports. Medicine 2024 Oct 15;5(10):101752
Cell reports. Medicine 2024 Oct 15;5(10):101752
Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments.
Li X, Zheng K, Chen H, Li W
Current issues in molecular biology 2024 Oct 13;46(10):11359-11374
Current issues in molecular biology 2024 Oct 13;46(10):11359-11374
The miR-665/SOST Axis Regulates the Phenotypes of Bone Marrow Mesenchymal Stem Cells and Osteoporotic Symptoms in Female Mice.
Zeng X, Yuan X, Liao H, Wei Y, Wu Q, Zhu X, Li Q, Chen S, Hu M
The American journal of pathology 2024 Nov;194(11):2059-2075
The American journal of pathology 2024 Nov;194(11):2059-2075
Nine new nor-3,4-seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus and their hypoglycemic activity.
Wang M, Jiang S, Deng Y, Tian T, Zafar S, Xie Q, Yuan H, Jian Y, Wang W
Bioorganic chemistry 2024 Nov;152:107763
Bioorganic chemistry 2024 Nov;152:107763
The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism.
Chen L, Zhang K, Liu J, Li X, Liu Y, Ma H, Yang J, Li J, Chen L, Hsu C, Zeng J, Xie X, Wang Q
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4832-4857
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4832-4857
Fast freezing inhibits melanin synthesis of melanocytes by modulating the Wnt/β-catenin signalling pathway.
Wu S, Yuan X, Tang Z, Zang K, Wang C, Li Z, Li H, Ye X, Dang Y
Experimental dermatology 2024 May;33(5):e15101
Experimental dermatology 2024 May;33(5):e15101
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Liu J, Wei AH, Liu TT, Ji XH, Zhang Y, Yan F, Chen MX, Hu JB, Zhou SY, Shi JS, Jin H, Jin F
The FEBS journal 2024 May;291(10):2221-2241
The FEBS journal 2024 May;291(10):2221-2241
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Sun H, Wang X, Ma L, Li X, Jin W, Yang Y
Experimental and therapeutic medicine 2024 May;27(5):197
Experimental and therapeutic medicine 2024 May;27(5):197
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Wu Q, Gao X, Lin Y, Wu C, Zhang J, Chen M, Wen J, Wu Y, Tian K, Bao W, Sun P, Zhu A
Toxics 2024 May 7;12(5)
Toxics 2024 May 7;12(5)
Nur77 inhibition of β-catenin expression mediates Hepatoblastoma progression and enhances cisplatin's therapeutic effect.
Zhou J, Liu X, Yin H, Zhou Y, Xu Z, Zhou K, Li T, Fang Y, Shen Q
Gene 2024 May 25;908:148292
Gene 2024 May 25;908:148292
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Xie W, Deng L, Qian R, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
Shang NY, Huang LJ, Lan JQ, Kang YY, Tang JS, Wang HY, Li XN, Sun Z, Chen QY, Liu MY, Wen ZP, Feng XH, Wu L, Peng Y
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer.
Shan W, Peng W, Chen Y, Wang Y, Yu Q, Tian Y, Dou Y, Tu J, Huang X, Li X, Wang Z, Zhu Q, Chen J, Xia B
Oncogene 2024 Jun;43(25):1885-1899
Oncogene 2024 Jun;43(25):1885-1899
Scutellarin alleviates microglia-mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathway.
Duan Z, Chen H, Miao W, He J, Xu D, Qi Z, Yang L, Jia W, Wu C
Journal of cell communication and signaling 2024 Jun;18(2):e12023
Journal of cell communication and signaling 2024 Jun;18(2):e12023
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
Li Y, Mei Z, Deng P, Zhou S, Qian A, Zhang X, Li J
Cellular signalling 2024 Jun;118:111147
Cellular signalling 2024 Jun;118:111147
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Wei H, Li W, Zeng L, Ding N, Li K, Yu H, Jiang F, Yin H, Xia Y, Deng C, Cai N, Chen X, Gu L, Chen H, Zhang F, He Y, Li J, Zhang C
Molecular cancer 2024 Jun 7;23(1):124
Molecular cancer 2024 Jun 7;23(1):124
CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer.
Zhong C, Jiang WJ, Yao Y, Li Z, Li Y, Wang S, Wang X, Zhu W, Wu S, Wang J, Fan S, Ma S, Liu Y, Zhang H, Zhao W, Zhao L, Feng Y, Li Z, Guo R, Yu L, Pei F, Hu J, Feng X, Yang Z, Yang Z, Yang X, Hou Y, Zhang D, Xu D, Sheng R, Li Y, Liu L, Wu HJ, Huang J, Fei T
Nature communications 2024 Jun 29;15(1):5502
Nature communications 2024 Jun 29;15(1):5502
Gold Nanoparticle Delivery of Glut1 SiRNA Facilitates Glucose Starvation Therapy in Lung Cancer.
Li J, Yu J, Fang Q, Du Y, Zhang X
Chembiochem : a European journal of chemical biology 2024 Jun 17;25(12):e202400239
Chembiochem : a European journal of chemical biology 2024 Jun 17;25(12):e202400239
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
Jing LP, Li M, Xia XY, Zheng X, Chen JY, He J, Zhuang XW
Heliyon 2024 Jun 15;10(11):e31487
Heliyon 2024 Jun 15;10(11):e31487
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Dong W, Lin M, Zhang R, Sun X, Li H, Liu T, Xu Y, Lv L
Cancer letters 2024 Jun 1;591:216883
Cancer letters 2024 Jun 1;591:216883
Idebenone protects the kidneys of rats with renovascular arterial hypertension by inhibiting oxidative stress and apoptosis.
He J, Huang L, Lu L
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jul 28;70(7):180-185
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jul 28;70(7):180-185
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
Tuo H, Li X, Du H, Li M, Xu C, Yu Z, Zhao H
Molecular carcinogenesis 2024 Jan;63(1):34-44
Molecular carcinogenesis 2024 Jan;63(1):34-44
Baizhu shaoyao decoction restores the intestinal barrier and brain-gut axis balance to alleviate diarrhea-predominant irritable bowel syndrome via FoxO1/FoxO3a.
Wei Y, Fan Y, Huang S, Lv J, Zhang Y, Hao Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155163
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155163
Effects of monochromatic light on hepatic glycogen and lipid synthesis in broilers.
Wang L, Wang Z, Chen Y, Cao J
Poultry science 2024 Jan;103(1):103193
Poultry science 2024 Jan;103(1):103193
MALAT1/miR-7-5p/TCF4 Axis Regulating Menstrual Blood Mesenchymal Stem Cells Improve Thin Endometrium Fertility by the Wnt Signaling Pathway.
Wang H, Chen K, Zong L, Zhao X, Wang J, Fan S, Shen B, Zheng S
Cell transplantation 2024 Jan-Dec;33:9636897241259552
Cell transplantation 2024 Jan-Dec;33:9636897241259552
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway.
Du Y, Yan T, Wu B, He B, Jia Y
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117190
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117190
β-carboline derivative Z86 attenuates colorectal cancer cell proliferation and migration by directly targeting PI3K.
Nie S, Chang L, Huang Y, Zhou H, Yang Q, Kong L, Li Y
Natural products and bioprospecting 2024 Jan 3;14(1):3
Natural products and bioprospecting 2024 Jan 3;14(1):3
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.
Zhou Z, Zhang B, Deng Y, Deng S, Li J, Wei W, Wang Y, Wang J, Feng Z, Che M, Yang X, Meng J, Li Y, Hu Y, Sun Y, Wen L, Huang F, Sheng Y, Wan C, Yang K
Journal of experimental & clinical cancer research : CR 2024 Jan 29;43(1):34
Journal of experimental & clinical cancer research : CR 2024 Jan 29;43(1):34
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Li Z, Shan X, Yang G, Dong L
International immunopharmacology 2024 Jan 25;127:111458
International immunopharmacology 2024 Jan 25;127:111458
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Wu LR, Peng QY, Li XJ, Guo MY, He JQ, Ying HZ, Yu CH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Lin S, Chen Z, Wu Z, Fei F, Xu Z, Tong Y, Sun W, Wang P
Neurochemical research 2024 Feb;49(2):477-491
Neurochemical research 2024 Feb;49(2):477-491
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy.
Zhao R, Liu M, Dai E, Chen C, Lv L, Peng L, He Y, Li S, Yang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23493
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23493
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Zhen Z, Wei S, Yunfei W, Jie X, Jienan X, Yiting S, Wen X, Shuyu G, Yue L, Xuanyu W, Yumei Z, Huafa Q
Heliyon 2024 Feb 29;10(4):e24644
Heliyon 2024 Feb 29;10(4):e24644
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Zhang W, Huang J, Shi J
Brain sciences 2024 Feb 28;14(3)
Brain sciences 2024 Feb 28;14(3)
WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating β-catenin signaling via promoting GSK3β ubiquitination.
Fang L, Tao Y, Che G, Yun Y, Ren M, Liu Y
Molecular medicine (Cambridge, Mass.) 2024 Feb 23;30(1):31
Molecular medicine (Cambridge, Mass.) 2024 Feb 23;30(1):31
DPPA2/4 Promote the Pluripotency and Proliferation of Bovine Extended Pluripotent Stem Cells by Upregulating the PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.
Fang S, Wang J, Liu G, Qu B, Chunyu J, Xu W, Xiang J, Li X
Cells 2024 Feb 23;13(5)
Cells 2024 Feb 23;13(5)
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Tao S, Cui D, Cheng H, Liu X, Jiang Z, Chen H, Gao Y
BMC cancer 2024 Feb 12;24(1):194
BMC cancer 2024 Feb 12;24(1):194
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Wu J, Shen Y, Wang P, Guo Z, Bai J, Wang X, Chen D, Lin X, Tang C
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
Zhang D, Lu C, Zhou Y, Luo X, Guo H, Zhang J, Gao Q, Liu H, Shang C, Cui S
Biology of reproduction 2024 Feb 10;110(2):246-260
Biology of reproduction 2024 Feb 10;110(2):246-260
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Aloe Emodin Alleviates Radiation-Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption.
Ouyang F, Li Y, Wang H, Liu X, Tan X, Xie G, Zeng J, Zeng G, Luo Q, Zhou H, Chen S, Hou K, Fang J, Zhang X, Zhou L, Li Y, Gao A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406026
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406026
Melatonin nuclear receptors mediate monochromatic light-induced T-lymphocyte proliferation of thymus through the AKT/GSK3β/β-catenin pathway in chick.
Xiong J, Wang Z, Dong Y, Cao J, Chen Y
Poultry science 2024 Dec;103(12):104507
Poultry science 2024 Dec;103(12):104507
Albiflorin inhibits osteoclastogenesis and titanium particles-induced osteolysis via inhibition of ROS accumulation and the PI3K/AKT signaling pathway.
Wang Q, Tao H, Wang H, Chen K, Zhu P, Chen W, Shi F, Gu Y, Xu Y, Geng D
International immunopharmacology 2024 Dec 5;142(Pt B):113245
International immunopharmacology 2024 Dec 5;142(Pt B):113245
SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 Axis.
E H, Zhang L, Yang Z, Xu L, Wang T, Guo J, Xia L, Yu J, Wang H, She Y, Wu J, Zhao Y, Chen C, Zhao D
Journal of experimental & clinical cancer research : CR 2024 Dec 19;43(1):324
Journal of experimental & clinical cancer research : CR 2024 Dec 19;43(1):324
Osteoblast-derived exosomal miR-140-3p targets ACER2 and increases the progression of prostate cancer via the AKT/mTOR pathway-mediated inhibition of autophagy.
Liu Y, Chen S, Guo K, Ma S, Wang X, Liu Q, Yan R, Huang Y, Li T, He S, Hui J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70206
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70206
Nur77 as a novel regulator of Paneth cell differentiation and function.
Cui C, Wang X, Zheng Y, Wu L, Li L, Wei H, Peng J
Mucosal immunology 2024 Aug;17(4):752-767
Mucosal immunology 2024 Aug;17(4):752-767
Protective effects of chlorogenic acid on the intestinal barrier of broiler chickens: an immunological stress model study.
Zha P, Liu W, Zhou Y, Chen Y
Poultry science 2024 Aug;103(8):103949
Poultry science 2024 Aug;103(8):103949
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation.
Bai Y, Li R, Hao JF, Chen LW, Liu ST, Zhang XL, Lip GYH, Yang JK, Zou YX, Wang H
Journal of translational medicine 2024 Aug 5;22(1):734
Journal of translational medicine 2024 Aug 5;22(1):734
Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection.
Peña-Díaz S, Chao JD, Rens C, Haghdadi H, Zheng X, Flanagan K, Ko M, Shapira T, Richter A, Maestre-Batlle D, Canseco JO, Gutierrez MG, Duc KD, Pelech S, Av-Gay Y
iScience 2024 Aug 16;27(8):110555
iScience 2024 Aug 16;27(8):110555
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Wang N, Guo W, Liu T, Chen X, Lin M
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring.
Li J, Zhang S, Sun Y, Li J, Feng Z, Li H, Zhang M, Yan T, Han J, Duan Y
EMBO reports 2024 Apr;25(4):2097-2117
EMBO reports 2024 Apr;25(4):2097-2117
Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation.
Cheng F, Zhang J, Yang P, Chen Z, Fu Y, Mi J, Xie X, Liu S, Sheng Y
Heliyon 2024 Apr 30;10(8):e29162
Heliyon 2024 Apr 30;10(8):e29162
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Pharmacodynamic material basis and pharmacological mechanisms of Cortex Mori against diabetes mellitus.
Li N, Du X, Qu T, Ren H, Lu W, Cui X, Hu J, Chen Z, Tao H
Journal of ethnopharmacology 2024 Apr 24;324:117781
Journal of ethnopharmacology 2024 Apr 24;324:117781
Lycium Barbarum Polysaccharides Improves Cognitive Functions in ICV-STZ-Induced Alzheimer's Disease Mice Model by Improving the Synaptic Structural Plasticity and Regulating IRS1/PI3K/AKT Signaling Pathway.
He Y, Wang Y, Li X, Qi Y, Qu Z, Hu Y
Neuromolecular medicine 2024 Apr 23;26(1):15
Neuromolecular medicine 2024 Apr 23;26(1):15
Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway.
Yu J, Zhao Y, Xu L, Li W, Zhang H, Ping F, Li Y
Mediators of inflammation 2023;2023:8974960
Mediators of inflammation 2023;2023:8974960
Multifunctional Lithium-Doped Mesoporous Nanoparticles for Effective Dentin Regeneration in vivo.
Liang Z, Chen D, Jiang Y, Su Z, Pi Y, Luo T, Jiang Q, Yang L, Guo L
International journal of nanomedicine 2023;18:5309-5325
International journal of nanomedicine 2023;18:5309-5325
Ginsenoside Rb1 Promotes Hepatic Glycogen Synthesis to Ameliorate T2DM Through 15-PGDH/PGE(2)/EP4 Signaling Pathway.
Liang M, Zhan W, Wang L, Bei W, Wang W
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3223-3234
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3223-3234
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Tan X, Yang X, Xu X, Peng Y, Li X, Deng Y, Zhang X, Qiu W, Wu D, Ruan Y, Zhi C
Frontiers in chemistry 2023;11:1280999
Frontiers in chemistry 2023;11:1280999
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W
Oncogene 2023 Sep;42(38):2801-2815
Oncogene 2023 Sep;42(38):2801-2815
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism.
Lin Q, Guo Y, Li J, He S, Chen Y, Jin H
Marine drugs 2023 Sep 29;21(10)
Marine drugs 2023 Sep 29;21(10)
Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/β-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer.
Liu J, Zhang Q, Wang J, Wang C, Lan T, Wang T, Wang B
International journal of molecular sciences 2023 Sep 21;24(18)
International journal of molecular sciences 2023 Sep 21;24(18)
Exosomal miR-320e through wnt2targeted inhibition of the Wnt/β-catenin pathway allevisate cerebral small vessel disease and cognitive impairment.
Wang Z, Li XN, Yang SN, Wang Y, Gao KJ, Han B, Ma AJ
World journal of psychiatry 2023 Sep 19;13(9):630-644
World journal of psychiatry 2023 Sep 19;13(9):630-644
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Wang X, Yang J, Wang W, Li Y, Yang Y
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Sertoli cell-derived extracellular vesicles traverse the blood-testis barrier and deliver miR-24-3p inhibitor into germ cells improving sperm mobility.
Chen Y, Xu D, Ma Y, Chen P, Hu J, Chen D, Yu W, Han X
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:58-69
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:58-69
Sevoflurane anaesthesia induces cognitive impairment in young mice through sequential tau phosphorylation.
Liang F, Li M, Xu M, Zhang Y, Dong Y, Soriano SG, McCann ME, Yang G, Xie Z
British journal of anaesthesia 2023 Oct;131(4):726-738
British journal of anaesthesia 2023 Oct;131(4):726-738
Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/β-catenin signaling pathway.
Li T, Xiong X, Wang Y, Li Y, Liu Y, Zhang M, Li C, Yu T, Cao W, Chen S, Zhang H, Wang X, Lv L, Zhou Y, Liang H, Li X, Shan H
iScience 2023 Oct 20;26(10):107888
iScience 2023 Oct 20;26(10):107888
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Cai Y, Sun H, Song X, Zhao J, Xu D, Liu M
Aging 2023 Oct 19;15(20):11471-11488
Aging 2023 Oct 19;15(20):11471-11488
Voluntary wheel-running improved pulmonary fibrosis by reducing epithelial mesenchymal transformation.
Gao Y, Yang Z, He K, Wang Z, Zhang T, Yi J, Zhao L
Life sciences 2023 Oct 15;331:122066
Life sciences 2023 Oct 15;331:122066
Phenylethanoid glycosides derived from Cistanche deserticola promote neurological functions and the proliferation of neural stem cells for improving ischemic stroke.
Liu J, Wang Y, Li Q, Liu T, Liu X, Zhang H, Fu Z, Dai Y, Yang H, Wang Y, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115507
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115507
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway.
Yin L, Cao R, Liu Z, Luo G, Li Y, Zhou X, Chen X, Wu Y, He J, Zu X, Shen Y
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1770-1783
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1770-1783
Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Gioia MD, Poli V, Tan PJ, Spreafico R, Chu A, Cuenca AG, Gordts PL, Pandolfi L, Meloni F, Witztum JL, Chou J, Springstead JR, Zanoni I
bioRxiv : the preprint server for biology 2023 Nov 21;
bioRxiv : the preprint server for biology 2023 Nov 21;
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification.
Fan D, Ying Z, Yang Y, Qian Q, Li Y, Wang P, An X, Yan M
Journal of ethnopharmacology 2023 Nov 15;316:116774
Journal of ethnopharmacology 2023 Nov 15;316:116774
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Wang T, Huang X, Liu J, Liu W, Yang Z, He K, Chen J, Zhao L
Environmental toxicology 2023 May;38(5):1143-1152
Environmental toxicology 2023 May;38(5):1143-1152
Novel pathogenesis of post-traumatic stress disorder studied in transgenic mice.
Gong W, Li X, Feng Y, Ji M, Zhang D, Chen B, Wang S, Wu X, Cui L, Li B, Xia M
Journal of psychiatric research 2023 May;161:188-198
Journal of psychiatric research 2023 May;161:188-198
Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease.
Dong Y, Lu J, Zhang S, Chen L, Wen J, Wang F, Mao Y, Li L, Zhang J, Liao S, Dong L
Bioorganic chemistry 2023 May;134:106446
Bioorganic chemistry 2023 May;134:106446
Citrus alkaline extracts improve LPS-induced pulmonary fibrosis via epithelial mesenchymal transition signals.
Junjie L, Cheng G, Kangkang L, Yu L, Zhiyao Y, Xudong W, Xianmei Z, Xiaomin L
Chinese medicine 2023 May 29;18(1):62
Chinese medicine 2023 May 29;18(1):62
Nogo-B deficiency suppresses white adipogenesis by regulating β-catenin signaling.
Li J, Sun Y, Xue C, Yang X, Duan Y, Zhao D, Han J
Life sciences 2023 May 15;321:121571
Life sciences 2023 May 15;321:121571
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
Lan XB, Ni YS, Liu N, Wei W, Liu Y, Yang JM, Ma L, Bai R, Zhang J, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114266
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Zhao J, Liu J, Liu S, Tian S, Yuan H, Li S
Epigenomics 2023 Mar;15(6):369-383
Epigenomics 2023 Mar;15(6):369-383
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Zhao H, Tang S, Tao Q, Ming T, Lei J, Liang Y, Peng Y, Wang M, Liu M, Yang H, Ren S, Xu H
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Chen Z, He S, Lian S, Shen Y, Jiang W, Zhou L, Zhou L, Zhang X
Bioscience reports 2023 Mar 31;43(3)
Bioscience reports 2023 Mar 31;43(3)
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
Cao X, Wu S, Wang X, Huang J, Zhang W, Liang C
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression.
Ni B, Huang G, Yang R, Wang Z, Song H, Li K, Zhang Y, Wu K, Shi G, Wang X, Shen J, Liu Y
Journal of neuroinflammation 2023 Mar 21;20(1):80
Journal of neuroinflammation 2023 Mar 21;20(1):80
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Li Z, Zeng M, Geng K, Lai D, Xu Z, Zhou W
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.
Guo H, Zhang D, Zhou Y, Sun L, Li C, Luo X, Liu J, Cui S
Endocrinology 2023 Mar 13;164(5)
Endocrinology 2023 Mar 13;164(5)
Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis.
Liu X, Jiang L, Zhang W, Zhang J, Luan X, Zhan Y, Wang T, Da J, Liu L, Zhang S, Guo Y, Zhang K, Wang Z, Miao N, Xie X, Liu P, Li Y, Jin H, Zhang B
Journal of translational medicine 2023 Jun 27;21(1):417
Journal of translational medicine 2023 Jun 27;21(1):417
GSK3β-driven SOX2 overexpression is a targetable vulnerability in esophageal squamous cell carcinoma.
Kang L, Liu Y, He J, Wang Y, Xue M, Wu X, Wang Z, Zhang Y, Chu M, Li J, Wei W, Li J, Li E, Liao L, Xiao J, Zhang R, Xu L, Wong J
Oncogene 2023 Jul;42(30):2297-2314
Oncogene 2023 Jul;42(30):2297-2314
Curcumin-Containing polyphosphazene nanodrug for Anti-Inflammation and nerve regeneration to improve functional recovery after spinal cord injury.
Su X, Jing X, Jiang W, Li M, Liu K, Teng M, Wang D, Meng L, Zhang Y, Ji W
International journal of pharmaceutics 2023 Jul 25;642:123197
International journal of pharmaceutics 2023 Jul 25;642:123197
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J
Cell 2023 Jul 20;186(15):3208-3226.e27
Cell 2023 Jul 20;186(15):3208-3226.e27
Regulation of Sertoli cell function by planar cell polarity (PCP) protein Fjx1.
Bu T, Li X, Wang L, Wu X, Gao S, Yun D, Li L, Sun F, Cheng CY
Molecular and cellular endocrinology 2023 Jul 1;571:111936
Molecular and cellular endocrinology 2023 Jul 1;571:111936
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
Du C, Dong J, Wang Q, Xu C, Feng S, Feng R, Lv X, Li J, Zhang L, Huang C, Ma T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154585
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154585
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Fan G, Wang F, Chen Y, Zheng Q, Xiong J, Lv Q, Wu K, Xiong J, Wei L, Li D, Zhang J, Zhang W, Li F
Cell reports 2023 Jan 31;42(1):111916
Cell reports 2023 Jan 31;42(1):111916
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice.
Liu H, Ju A, Dong X, Luo Z, Tang J, Ma B, Fu Y, Luo Y
Journal of translational medicine 2023 Feb 6;21(1):89
Journal of translational medicine 2023 Feb 6;21(1):89
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Berberine protects mice against type 2 diabetes by promoting PPARγ-FGF21-GLUT2-regulated insulin sensitivity and glucose/lipid homeostasis.
Chen Y, Li Q, Zhao S, Sun L, Yin Z, Wang X, Li X, Iwakiri Y, Han J, Duan Y
Biochemical pharmacology 2023 Dec;218:115928
Biochemical pharmacology 2023 Dec;218:115928
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Bao S, Chen T, Chen J, Zhang J, Zhang G, Hui Y, Li J, Yan S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Bi X, Zhang M, Zhou J, Yan X, Cheng L, Luo L, Huang C, Yin Z
Cellular signalling 2023 Dec;112:110913
Cellular signalling 2023 Dec;112:110913
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
Kuang H, Li Y, Wang Y, Shi M, Duan R, Xiao Q, She H, Liu Y, Liang Q, Teng Y, Zhou M, Liang D, Li Z, Wu L
Cell reports 2023 Dec 26;42(12):113445
Cell reports 2023 Dec 26;42(12):113445
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Cheng T, Agwu C, Shim K, Wang B, Jain S, Mahjoub MR
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
Overexpression of FSP1 Ameliorates ferroptosis via PI3K/ AKT /GSK3β pathway in PC12 cells with Oxygen-Glucose Deprivation/Reoxygenation.
Wu Y, Shi H, Zheng J, Yang Y, Lei X, Qian X, Zhu J
Heliyon 2023 Aug;9(8):e18449
Heliyon 2023 Aug;9(8):e18449
Hydrogel-based miR-192 delivery inhibits the development of hepatocellular carcinoma by suppressing the GSK3β/Wnt/β-catenin pathway.
Yang Q, Zhuge X, Lin W, Yu W, Zhu Y, Shi C, Shi Z
Neoplasma 2023 Aug;70(4):555-565
Neoplasma 2023 Aug;70(4):555-565
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Oncogene 2023 Aug;42(32):2439-2455
Oncogene 2023 Aug;42(32):2439-2455
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
Wei Y, Liu W, Liu J
Environment international 2023 Aug;178:108090
Environment international 2023 Aug;178:108090
The 15-hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates abnormal hepatic glucose metabolism through PGE(2)-EP4 receptor-AKT signaling in a type 2 diabetes mellitus mouse model.
Liang M, Wang L, Wang W
Cellular signalling 2023 Aug;108:110707
Cellular signalling 2023 Aug;108:110707
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells.
Ma Y, Liu L, Wei Z, Zhu M, Huang L, Wang S, Yi X, Ying F, Zhao S, Cai J, Wang Z, Sun S
Molecular carcinogenesis 2023 Apr;62(4):479-492
Molecular carcinogenesis 2023 Apr;62(4):479-492
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Gao X, Kang J, Li X, Chen C, Luo D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Zhang W, Zhang M, Wu Q, Shi J
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
Zang H, Shao G, Lou Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9630716
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9630716
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Yang X, Luo G, Fu L, Huang H, Wang L, Yin L, Zhang X, Wang T, Ma X, Feng T, Ye J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice.
Peng Y, Chi R, Liu G, Tian W, Zhang J, Zhang R
Neural plasticity 2022;2022:1500710
Neural plasticity 2022;2022:1500710
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
Zhang Z, Xu P, Hu Z, Fu Z, Deng T, Deng X, Peng L, Xie Y, Long L, Zheng D, Shen P, Zhang M, Gong B, Zhu Z, Lin J, Chen R, Liu Z, Yang H, Li R, Fang W
International journal of biological sciences 2022;18(10):4171-4186
International journal of biological sciences 2022;18(10):4171-4186
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology.
Li M, Wang Y, Qi Z, Yuan Z, Lv S, Zheng Y, Yan Z, Wang M, Fu H, Fan X, Ji N, Liu M, Fang Z
Frontiers in pharmacology 2022;13:981206
Frontiers in pharmacology 2022;13:981206
Resveratrol Targets AKT1 to Inhibit Inflammasome Activation in Cardiomyocytes Under Acute Sympathetic Stress.
Wang R, Wang Y, Wu J, Guo Y, Xiao H, Zhang Y, Ma K
Frontiers in pharmacology 2022;13:818127
Frontiers in pharmacology 2022;13:818127
Empagliflozin Inhibits Hepatic Gluconeogenesis and Increases Glycogen Synthesis by AMPK/CREB/GSK3β Signalling Pathway.
Yu X, Meng Z, Fang T, Liu X, Cheng Y, Xu L, Liu X, Li X, Xue M, Li T, Sun B, Chen L
Frontiers in physiology 2022;13:817542
Frontiers in physiology 2022;13:817542
Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer's Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.
Huang Q, Zhang C, Qu S, Dong S, Ma Q, Hao Y, Liu Z, Wang S, Zhao H, Shi Y
Frontiers in pharmacology 2022;13:817213
Frontiers in pharmacology 2022;13:817213
A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair.
Wang Z, Jia S, Xu H, Wang X, Lu B, Wu W, Huang D, Kong L, Kang X, Tian F, Zhu L, Hao D
Theranostics 2022;12(17):7567-7585
Theranostics 2022;12(17):7567-7585
Pan-cancer analysis of trophinin-associated protein with potential implications in clinical significance, prognosis, and tumor microenvironment in human cancers.
Li Z, Pu Z, Yang Z, Zhu Y, Deng Y, Li N, Peng F
Frontiers in oncology 2022;12:971618
Frontiers in oncology 2022;12:971618
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Lei Q, Yu Z, Li H, Cheng J, Wang Y
Journal of advanced research 2022 Sep;40:197-206
Journal of advanced research 2022 Sep;40:197-206
Aqueous extract of Scrophularia ningpoensis improves insulin sensitivity through AMPK-mediated inhibition of the NLRP3 inflammasome.
Yan S, Lu W, Zhou J, Guo X, Li J, Cheng H, Zhu X, Zhao Y, Duan M, Yang H, Zhang Y, Wang Q, Chen L, Zheng T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154308
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154308
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Zhang XG, Liu AX, Zhang YX, Zhou MY, Li XY, Fu MH, Pan YP, Xu J, Zhang JQ
Journal of ethnopharmacology 2022 Sep 15;295:115397
Journal of ethnopharmacology 2022 Sep 15;295:115397
A novel O(2)- (2,4-dinitrophenyl) diazeniumdiolate inhibits hepatocellular carcinoma migration, invasion, and EMT through the Wnt/β-catenin pathway.
Xing Y, Hu Y, Zou H, Xie H, Jiang T, Liu L
Toxicology in vitro : an international journal published in association with BIBRA 2022 Oct;84:105456
Toxicology in vitro : an international journal published in association with BIBRA 2022 Oct;84:105456
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β.
Chen LJ, Wu L, Wang W, Zhai LL, Xiang F, Li WB, Tang ZG
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
Pan C, Qin H, Jin H, Chen W, Guo H, Han X
Toxicology 2022 Oct;480:153326
Toxicology 2022 Oct;480:153326
GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state via GSK-3β pathway.
Çiçekli MN, Tiryaki ES, Altun A, Günaydın C
Journal of receptor and signal transduction research 2022 Oct;42(5):486-494
Journal of receptor and signal transduction research 2022 Oct;42(5):486-494
Inhibition of NLRP1-Dependent Pyroptosis Prevents Glycogen Synthase Kinase-3β Overactivation-Induced Hyperphosphorylated Tau in Rats.
Liu X, Song W, Yu Y, Su J, Shi X, Yang X, Wang H, Liu P, Zou L
Neurotoxicity research 2022 Oct;40(5):1163-1173
Neurotoxicity research 2022 Oct;40(5):1163-1173
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Chen X, Liu Q, Chen Y, Wang L, Yang R, Zhang W, Pan X, Zhang S, Chen C, Wu T, Xia J, Cheng B, Chen X, Ren X
Molecular metabolism 2022 Nov;65:101600
Molecular metabolism 2022 Nov;65:101600
Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells.
Luo F, Li J, Liu J, Liu K
Cancer gene therapy 2022 Nov;29(11):1707-1719
Cancer gene therapy 2022 Nov;29(11):1707-1719
Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats.
Yuan C, Zheng L, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113664
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113664
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Yao R, Zhang M, Zhou J, Liu L, Zhang Y, Gao J, Xu K
Cell communication and signaling : CCS 2022 May 26;20(1):73
Cell communication and signaling : CCS 2022 May 26;20(1):73
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2022 Mar;49(3):1871-1882
Molecular biology reports 2022 Mar;49(3):1871-1882
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt-β-catenin-STAT3 signaling.
Hu S, Ren S, Cai Y, Liu J, Han Y, Zhao Y, Yang J, Zhou X, Wang X
Cell death and differentiation 2022 Mar;29(3):642-656
Cell death and differentiation 2022 Mar;29(3):642-656
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma.
Chen X, Wang K, Jiang S, Sun H, Che X, Zhang M, He J, Wen Y, Liao M, Li X, Zhou X, Song J, Ren X, Yi W, Yang J, Chen X, Yin M, Cheng Y
Journal for immunotherapy of cancer 2022 Mar;10(3)
Journal for immunotherapy of cancer 2022 Mar;10(3)
Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway.
Wang X, Tian Y, Liang X, Yin C, Huai Y, Zhao Y, Huang Q, Chu X, Wang W, Qian A
Food & function 2022 Mar 7;13(5):2913-2924
Food & function 2022 Mar 7;13(5):2913-2924
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Wei P, Jiang J, Xiao M, Zeng M, Liu X, Zhao B, Chen F
Experimental cell research 2022 Mar 1;412(1):113009
Experimental cell research 2022 Mar 1;412(1):113009
Dok5 regulates proliferation and differentiation of osteoblast via canonical Wnt/β-catenin signaling.
Xu L, Wu J, Yu Y, Li H, Sun S, Zhang T, Wang M
Journal of musculoskeletal & neuronal interactions 2022 Mar 1;22(1):113-122
Journal of musculoskeletal & neuronal interactions 2022 Mar 1;22(1):113-122
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Zhang Y, Wu Z, Huang Z, Liu Y, Chen X, Zhao X, He H, Deng Y
Brain research 2022 Mar 1;1778:147768
Brain research 2022 Mar 1;1778:147768
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Chen Z, Tian L, Wang L, Ma X, Lei F, Chen X, Fu R
Inflammation 2022 Jun;45(3):992-1006
Inflammation 2022 Jun;45(3):992-1006
Restraint of FAM60A has a cancer-inhibiting role in pancreatic carcinoma via the effects on the Akt/GSK-3β/β-catenin signaling pathway.
Zhang Y, Li JH, Yuan QG, Yang WB
Environmental toxicology 2022 Jun;37(6):1432-1444
Environmental toxicology 2022 Jun;37(6):1432-1444
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Wang Y, Jin C, Tian H, Xu J, Chen J, Hu S, Li Q, Lu L, Ou Q, Xu GT, Cui H
Experimental eye research 2022 Jun;219:108939
Experimental eye research 2022 Jun;219:108939
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Zhong T, Li M, Wu H, Wang D, Liu J, Xu Y, Fan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
A novel frameshift variant in the TSPAN12 gene causes autosomal dominant FEVR.
Peng L, Dai E, Xiao H, Zhao R, He Y, Li S, Yang M, Yang Z, Zhao P
Molecular genetics & genomic medicine 2022 Jun;10(6):e1949
Molecular genetics & genomic medicine 2022 Jun;10(6):e1949
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Yin BF, Li ZL, Yan ZQ, Guo Z, Liang JW, Wang Q, Zhao ZD, Li PL, Hao RC, Han MY, Li XT, Mao N, Ding L, Chen DF, Gao Y, Zhu H
Stem cell research & therapy 2022 Jun 7;13(1):241
Stem cell research & therapy 2022 Jun 7;13(1):241
Insulin and liraglutide attenuate brain pathology in diabetic mice by enhancing the Wnt/β-catenin signaling pathway.
Zhao Y, Yu J, Ping F, Xu L, Li W, Zhang H, Li Y
Experimental and therapeutic medicine 2022 Jul;24(1):439
Experimental and therapeutic medicine 2022 Jul;24(1):439
Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways.
Wu Y, Sun Z, Wang T, Wang Y, Zhong L, Kong F
International immunopharmacology 2022 Jul;108:108912
International immunopharmacology 2022 Jul;108:108912
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Huang Q, Zhang C, Dong S, Han J, Qu S, Xie T, Zhao H, Shi Y
Chinese medicine 2022 Jul 6;17(1):83
Chinese medicine 2022 Jul 6;17(1):83
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Shu S, Kobayashi M, Marunaka K, Yoshino Y, Goto M, Katsuta Y, Ikari A
Cells 2022 Jul 22;11(15)
Cells 2022 Jul 22;11(15)
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
Zhang L, Ren CF, Yang Z, Gong LB, Wang C, Feng M, Guan WX
Journal of translational medicine 2022 Jul 21;20(1):327
Journal of translational medicine 2022 Jul 21;20(1):327
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Wen Y, Liu Y, Huang Q, Liu R, Liu J, Zhang F, Liu S, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Blue Light Alters the Composition of the Jejunal Microbiota and Promotes the Development of the Small Intestine by Reducing Oxidative Stress.
Zhang Y, Wang Z, Dong Y, Cao J, Chen Y
Antioxidants (Basel, Switzerland) 2022 Jan 29;11(2)
Antioxidants (Basel, Switzerland) 2022 Jan 29;11(2)
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Wu ZL, Chen YJ, Zhang GZ, Xie QQ, Wang KP, Yang X, Liu TC, Wang ZQ, Zhao GH, Zhang HH
Apoptosis : an international journal on programmed cell death 2022 Feb;27(1-2):133-148
Apoptosis : an international journal on programmed cell death 2022 Feb;27(1-2):133-148
Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder.
Liu J, Zhou L, Zhao F, Zhou C, Yang T, Xu Z, Wang X, Xu L, Xu Z, Ge Y, Wu R, Jia R
Stem cell research & therapy 2022 Feb 9;13(1):68
Stem cell research & therapy 2022 Feb 9;13(1):68
The neuroprotective mechanism of lithium after ischaemic stroke.
Chen B, Zhang M, Ji M, Zhang D, Chen B, Gong W, Li X, Zhou Y, Dong C, Wen G, Zhan X, Wu X, Yuan H, Xu E, Xia M, Verkhratsky A, Li B
Communications biology 2022 Feb 3;5(1):105
Communications biology 2022 Feb 3;5(1):105
Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway.
Han W, Wang N, Kong R, Bao W, Lu J
Journal of translational medicine 2022 Feb 12;20(1):86
Journal of translational medicine 2022 Feb 12;20(1):86
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Han QJ, Han G, Peng J, Tang Z
Free radical biology & medicine 2022 Feb 1;179:416-417
Free radical biology & medicine 2022 Feb 1;179:416-417
Role of TRPV1 channels on glycogen synthase kinase-3β and oxidative stress in ouabain-induced bipolar disease.
Kukula O, Çiçekli MN, Şafak S, Günaydın C
Journal of receptor and signal transduction research 2022 Aug;42(4):338-348
Journal of receptor and signal transduction research 2022 Aug;42(4):338-348
Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.
Liu Q, Luo Q, Feng J, Zhao Y, Ma B, Cheng H, Zhao T, Lei H, Mu C, Chen L, Meng Y, Zhang J, Long Y, Su J, Chen G, Li Y, Hu G, Liao X, Chen Q, Zhu Y
eLife 2022 Aug 1;11
eLife 2022 Aug 1;11
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Ruan Y, Xu H, Ji X
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Functionalized gadofullerene ameliorates impaired glycolipid metabolism in type 2 diabetic mice.
Wu J, Chen Y, Li X, Ran L, Liu X, Wang X, Zhen M, Shao S, Zeng L, Wang C, Liang B, Zhao J, Wu Y
Journal of genetics and genomics = Yi chuan xue bao 2022 Apr;49(4):364-376
Journal of genetics and genomics = Yi chuan xue bao 2022 Apr;49(4):364-376
FAM83A has a pro-tumor function in ovarian cancer by affecting the Akt/Wnt/β-catenin pathway.
Zhao J, Zhao F, Yang T, Tian S, Zhao M, Wang S, Yang X
Environmental toxicology 2022 Apr;37(4):695-707
Environmental toxicology 2022 Apr;37(4):695-707
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420
Food & function 2022 Apr 20;13(8):4399-4420
Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer.
Kołat D, Kałuzińska Ż, Bednarek AK, Płuciennik E
Cells 2022 Apr 19;11(9)
Cells 2022 Apr 19;11(9)
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962
Frontiers in medicine 2021;8:630962
Periostin regulates osteogenesis of mesenchymal stem cells from ovariectomized rats through actions on the ILK/Akt/GSK-3β Axis.
Liu S, Jin Z, Cao M, Hao D, Li C, Li D, Zhou W
Genetics and molecular biology 2021;44(3):e20200461
Genetics and molecular biology 2021;44(3):e20200461
Apelin/APJ-Manipulated CaMKK/AMPK/GSK3β Signaling Works as an Endogenous Counterinjury Mechanism in Promoting the Vitality of Random-Pattern Skin Flaps.
Lou ZL, Zhang CX, Li JF, Chen RH, Wu WJ, Hu XF, Shi HC, Gao WY, Zhao QF
Oxidative medicine and cellular longevity 2021;2021:8836058
Oxidative medicine and cellular longevity 2021;2021:8836058
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Zhang Y, Chen G, Zhuang X, Guo M
Oxidative medicine and cellular longevity 2021;2021:8807676
Oxidative medicine and cellular longevity 2021;2021:8807676
A Green and Blue Monochromatic Light Combination Therapy Reduces Oxidative Stress and Enhances B-Lymphocyte Proliferation through Promoting Melatonin Secretion.
Zhang Y, Wang Z, Cao J, Dong Y, Chen Y
Oxidative medicine and cellular longevity 2021;2021:5595376
Oxidative medicine and cellular longevity 2021;2021:5595376
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Ning WJ, Lv RJ, Xu N, Hou XY, Shen C, Guo YL, Fan ZY, Cao N, Liu XP
Neural plasticity 2021;2021:5519330
Neural plasticity 2021;2021:5519330
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
Liu Y, Li W, Luo J, Wu Y, Xu Y, Chen T, Zhang W, Fu F
Disease markers 2021;2021:3566749
Disease markers 2021;2021:3566749
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Ding L, Ren C, Yang L, Wu Z, Li F, Jiang D, Zhu Y, Lu J
Drug design, development and therapy 2021;15:1797-1810
Drug design, development and therapy 2021;15:1797-1810
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Wang Z, Yan H, Cheng D, Xu L, Shen T, Chen Y, Han R, Xue Y
Cancer management and research 2021;13:8387-8397
Cancer management and research 2021;13:8387-8397
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
Feng Y, Le F, Tian P, Zhong Y, Zhan F, Huang G, Hu H, Chen T, Tan B
Journal of Cancer 2021;12(5):1386-1397
Journal of Cancer 2021;12(5):1386-1397
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Cheng X, Qin L, Deng L, Zhu X, Li Y, Wu X, Zheng Y
Journal of Cancer 2021;12(19):5825-5837
Journal of Cancer 2021;12(19):5825-5837
Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.
Cao T, Chen Q, Zhang B, Wu X, Zeng C, Zhang S, Cai H
Frontiers in endocrinology 2021;12:727371
Frontiers in endocrinology 2021;12:727371
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop.
Lin J, Zeng C, Zhang J, Song Z, Qi N, Liu X, Zhang Z, Li A, Chen F
Molecular therapy. Nucleic acids 2021 Sep 3;25:328-341
Molecular therapy. Nucleic acids 2021 Sep 3;25:328-341
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Fang D, Wang MR, Guan JL, Han YY, Sheng JQ, Tian DA, Li PY
Experimental cell research 2021 Sep 15;406(2):112727
Experimental cell research 2021 Sep 15;406(2):112727
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
Liang N, Li S, Liang Y, Ma Y, Tang S, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
Li C, Cheng D, Xu P, Nie H, Zhang T, Pang X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Luo Z, Wang J, Zhu Y, Sun X, He C, Cai M, Ma J, Wang Y, Han S
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Duffy MP, Sup ME, Guo XE
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Exploring the synergistic mechanism of Gegen Qinlian Decoction on the Wnt signaling pathway using an integrated strategy of network pharmacology and RNA-seq.
Li Y, Gong Y, Zhang X, Wang J, Cheng Y, Liu F, Shi X, Xu W, Dong L
Journal of ethnopharmacology 2021 Oct 5;278:114283
Journal of ethnopharmacology 2021 Oct 5;278:114283
Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Ting HC, Yang HI, Harn HJ, Chiu IM, Su HL, Li X, Chen MF, Ho TJ, Liu CA, Tsai YJ, Chiou TW, Lin SZ, Chang CY
Cells 2021 Oct 16;10(10)
Cells 2021 Oct 16;10(10)
β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
Hidalgo-Gutiérrez A, Barriocanal-Casado E, Díaz-Casado ME, González-García P, Zenezini Chiozzi R, Acuña-Castroviejo D, López LC
Biomedicines 2021 Oct 13;9(10)
Biomedicines 2021 Oct 13;9(10)
SHP-1 acts as a tumor suppressor by interacting with EGFR and predicts the prognosis of human breast cancer.
Geng Q, Xian R, Yu Y, Chen F, Li R
Cancer biology & medicine 2021 Oct 1;19(4):468-85
Cancer biology & medicine 2021 Oct 1;19(4):468-85
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Wang L, Chen X, Wang L, Wang S, Li W, Liu Y, Zhang J
IUBMB life 2021 Nov;73(11):1378-1391
IUBMB life 2021 Nov;73(11):1378-1391
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Yang F, Chen R
Human & experimental toxicology 2021 Nov;40(11):1909-1920
Human & experimental toxicology 2021 Nov;40(11):1909-1920
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Xu X, Sun X, Wan X, Chen X, Jiang X
Toxicology letters 2021 Nov 1;352:61-69
Toxicology letters 2021 Nov 1;352:61-69
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, Qiu L, Cheng J, Ripley-Gonzalez JW, Liu S
Life sciences 2021 May 15;273:119314
Life sciences 2021 May 15;273:119314
Long noncoding RNA MEG3 expressed in human dental pulp regulates LPS-Induced inflammation and odontogenic differentiation in pulpitis.
Liu M, Chen L, Wu J, Lin Z, Huang S
Experimental cell research 2021 Mar 15;400(2):112495
Experimental cell research 2021 Mar 15;400(2):112495
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Lu D, Le Y, Ding J, Dou X, Mao W, Zhu J
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Zhang Z, Qin X, Wang Z, Li Y, Chen F, Chen R, Li C, Zhang W, Zhang M
Experimental and therapeutic medicine 2021 Jun;21(6):556
Experimental and therapeutic medicine 2021 Jun;21(6):556
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Xin C, Zhao M, Wang J, Wang Z
Journal of food biochemistry 2021 Jul;45(7):e13771
Journal of food biochemistry 2021 Jul;45(7):e13771
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer.
Zhang Z, Qin Y, Ji S, Xu W, Liu M, Hu Q, Ye Z, Fan G, Yu X, Liu W, Xu X
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):997-1008
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):997-1008
A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer's disease mechanisms.
Zeng P, Fang M, Zhao H, Guo J
Aging 2021 Jul 27;13(14):18993-19012
Aging 2021 Jul 27;13(14):18993-19012
Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor-dependent manner.
Zheng J, Ding J, Liao M, Qiu Z, Yuan Q, Mai W, Dai Y, Zhang H, Wu H, Wang Y, Liao Y, Chen X, Cheng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21157
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21157
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1.
Xing S, Tian Z, Zheng W, Yang W, Du N, Gu Y, Yin J, Liu H, Jia X, Huang D, Liu W, Deng M
Molecular cancer 2021 Jan 6;20(1):9
Molecular cancer 2021 Jan 6;20(1):9
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q
Nature communications 2021 Jan 20;12(1):476
Nature communications 2021 Jan 20;12(1):476
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, Huang M, Liu R, Lin Y, Tan C, Xu M, Zhang Z
Cell biology and toxicology 2021 Feb;37(1):35-49
Cell biology and toxicology 2021 Feb;37(1):35-49
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Dong X, Luo Y, Lu S, Ma H, Zhang W, Zhu Y, Sun G, Sun X
Clinical and translational medicine 2021 Feb;11(2):e296
Clinical and translational medicine 2021 Feb;11(2):e296
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Wang KX, Du GH, Qin XM, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Lu C, Liu L, Chen S, Niu J, Li S, Xie W, Cheng X
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847
Oncology letters 2021 Dec;22(6):847
Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice.
Yang Y, Liang F, Gao J, Dong Y, Zhang Y, Yang G, Soriano SG, Feng HJ, Xie Z
British journal of anaesthesia 2021 Dec;127(6):929-941
British journal of anaesthesia 2021 Dec;127(6):929-941
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
Zhao P, Cai Z, Tian Y, Li J, Li K, Li M, Bai Y, Li J
International immunopharmacology 2021 Dec;101(Pt B):108360
International immunopharmacology 2021 Dec;101(Pt B):108360
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Zhang L, Zhu T, He F, Li X
International immunopharmacology 2021 Dec;101(Pt B):108238
International immunopharmacology 2021 Dec;101(Pt B):108238
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
Zhu F, Shao J, Tian Y, Xu Z
International immunopharmacology 2021 Dec;101(Pt B):108221
International immunopharmacology 2021 Dec;101(Pt B):108221
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
Li J, Sun Y, Sun X, Zhao X, Ma Y, Wang Y, Zhang X
Scientific reports 2021 Aug 30;11(1):17348
Scientific reports 2021 Aug 30;11(1):17348
IARS2 regulates proliferation, migration, and angiogenesis of human umbilical vein endothelial cells.
Yu YM, Xu L, Li HR, Zhang TQ, Qian G, Li LF, Wang MH
Revista da Associacao Medica Brasileira (1992) 2021 Apr;67(4):555-560
Revista da Associacao Medica Brasileira (1992) 2021 Apr;67(4):555-560
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
Liu Y, Chen Y, Xie X, Yin A, Yin Y, Liu Y, Dong L, Zhu Z, Zhou J, Zeng Q, Lu X, Chen Z, Wen K, Zuo D
Oxidative medicine and cellular longevity 2020;2020:8096847
Oxidative medicine and cellular longevity 2020;2020:8096847
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer.
Kang D, Zuo W, Wu Q, Zhu Q, Liu P
BioMed research international 2020;2020:1358674
BioMed research international 2020;2020:1358674
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
Song Y, Yuan H, Wang J, Wu Y, Xiao Y, Mao S
Cancer management and research 2020;12:3981-3993
Cancer management and research 2020;12:3981-3993
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Chen M, Ji C, Yang Q, Gao S, Peng Y, Li Z, Gao X, Li Y, Jiang N, Zhang Y, Bian X, Chen C, Zhang K, Sanchis D, Yan F, Ye J
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3β/β-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats.
Luo X, Li L, Xu W, Cheng Y, Xie Z
Neuroscience bulletin 2020 Oct;36(10):1171-1181
Neuroscience bulletin 2020 Oct;36(10):1171-1181
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
Akt inhibition-dependent downregulation of the Wnt/β-Catenin Signaling pathway contributes to antimony-induced neurotoxicity.
Shi W, Tang Y, Zhi Y, Li Z, Yu S, Jiang J, Zhu J, Li J, Wang F, Su L, Zhao X
The Science of the total environment 2020 Oct 1;737:140252
The Science of the total environment 2020 Oct 1;737:140252
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Song J, Zhu XM, Wei QY
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
Wei J, Yu W, Hao R, Fan J, Gao J
Chemistry & biodiversity 2020 Nov;17(11):e2000654
Chemistry & biodiversity 2020 Nov;17(11):e2000654
The dynamic expression of canonical Wnt/β-catenin signalling pathway in the pathologic process of experimental autoimmune neuritis.
Liu Y, Liu S, Pan S, Gong Q, Yao J, Lu Z
The International journal of neuroscience 2020 Nov;130(11):1109-1117
The International journal of neuroscience 2020 Nov;130(11):1109-1117
Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure.
He F, Li L, Li PP, Deng Y, Yang YY, Deng YX, Luo HH, Yao XT, Su YX, Gan H, He BC
Aging 2020 Nov 6;12(21):21220-21235
Aging 2020 Nov 6;12(21):21220-21235
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Zhang H, Hui J, Yang J, Deng J, Fan D
European journal of pharmacology 2020 Nov 15;887:173557
European journal of pharmacology 2020 Nov 15;887:173557
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Li K, Pan WT, Ma YB, Xu XL, Gao Y, He YQ, Wei L, Zhang JW
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
Gang W, Tanjun W, Yong H, Jiajun Q, Yi Z, Hao H
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin.
Zhou L, Lu Y, Liu JS, Long SZ, Liu HL, Zhang J, Zhang T
Molecular and cellular probes 2020 Jun;51:101534
Molecular and cellular probes 2020 Jun;51:101534
ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.
Sun X, Peng X, Cao Y, Zhou Y, Sun Y
Nature communications 2020 Jun 12;11(1):2984
Nature communications 2020 Jun 12;11(1):2984
Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells.
Song J, Liu L, Lv L, Hu S, Tariq A, Wang W, Dang X
Cell biology international 2020 Jul;44(7):1491-1502
Cell biology international 2020 Jul;44(7):1491-1502
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
Wang SJ, Chao D, Wei W, Nan G, Li JY, Liu FL, Li L, Jiang JL, Cui HY, Chen ZN
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
Liu P, Zhu C, Luo J, Lan S, Su D, Wang Q, Wei Z, Cui W, Xu C, Yang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Lin L, Zeng L, Liu A, Peng Y, Yuan D, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Food & function 2020 Feb 26;11(2):1798-1809
Food & function 2020 Feb 26;11(2):1798-1809
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Amitriptyline Reduces Sepsis-Induced Brain Damage Through TrkA Signaling Pathway.
Zhang L, Peng X, Ai Y, Li L, Zhao S, Liu Z, Peng Q, Deng S, Huang Y, Mo Y, Huang L
Journal of molecular neuroscience : MN 2020 Dec;70(12):2049-2057
Journal of molecular neuroscience : MN 2020 Dec;70(12):2049-2057
miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway.
Tang Z, Chen W, Xu Y, Lin X, Liu X, Li Y, Liu Y, Luo Z, Liu Z, Fang W, Zhao M
Molecular therapy. Nucleic acids 2020 Dec 4;22:557-571
Molecular therapy. Nucleic acids 2020 Dec 4;22:557-571
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
He X, Huang X, Wang C, Luan M, Li Y, Ma X, Ma K
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, Yuan C, Xu J, Yan L, Hao H
International immunopharmacology 2020 Aug;85:106625
International immunopharmacology 2020 Aug;85:106625
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, Wang J, Sun L
IUBMB life 2020 Aug;72(8):1659-1679
IUBMB life 2020 Aug;72(8):1659-1679
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Liu Y, Wang H, Liu N, Du J, Lan X, Qi X, Zhuang C, Sun T, Li Y, Yu J
Life sciences 2020 Aug 1;254:116444
Life sciences 2020 Aug 1;254:116444
Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway.
Zhu M, Yu X, Zheng Z, Huang J, Yang X, Shi H
Phytotherapy research : PTR 2020 Apr;34(4):817-824
Phytotherapy research : PTR 2020 Apr;34(4):817-824
Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity.
Chen W, He B, Tong W, Zeng J, Zheng P
Frontiers in cellular neuroscience 2019;13:298
Frontiers in cellular neuroscience 2019;13:298
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
Guo L, Yang T
Cancer management and research 2019;11:10499-10508
Cancer management and research 2019;11:10499-10508
Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro.
Lu Z, Chang L, Zhou H, Liu X, Li Y, Mi T, Tong D
Frontiers in pharmacology 2019;10:937
Frontiers in pharmacology 2019;10:937
Mycoplasma hyorhinis infection promotes gastric cancer cell motility via β-catenin signaling.
Liu X, Rong Z, Shou C
Cancer medicine 2019 Sep;8(11):5301-5312
Cancer medicine 2019 Sep;8(11):5301-5312
Influence of Calcium Supplementation against Fluoride-Mediated Osteoblast Impairment in Vitro: Involvement of the Canonical Wnt/β-Catenin Signaling Pathway.
Wang J, Yang J, Cheng X, Yin F, Zhao Y, Zhu Y, Yan Z, Khodaei F, Ommati MM, Manthari RK, Wang J
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10285-10295
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10285-10295
Metformin reverses the schizophrenia-like behaviors induced by MK-801 in rats.
Wang X, Luo C, Mao XY, Li X, Yin JY, Zhang W, Zhou HH, Liu ZQ
Brain research 2019 Sep 15;1719:30-39
Brain research 2019 Sep 15;1719:30-39
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W
EBioMedicine 2019 Oct;48:386-404
EBioMedicine 2019 Oct;48:386-404
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y
Oncology reports 2019 Oct;42(4):1451-1458
Oncology reports 2019 Oct;42(4):1451-1458
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
Li K, Pan W, Ma Y, Xu X, Gao Y, He Y, Wei L, Zhang J
Pathology, research and practice 2019 Oct;215(10):152573
Pathology, research and practice 2019 Oct;215(10):152573
Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice.
Yang S, Chen Y, Duan Y, Ma C, Liu L, Li Q, Yang J, Li X, Zhao B, Wang Y, Qian K, Liu M, Zhu Y, Yang X, Han J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109389
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109389
XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/β-catenin signaling dependent way.
Xu D, Hou K, Li F, Chen S, Fang W, Li Y
Life sciences 2019 Oct 15;235:116844
Life sciences 2019 Oct 15;235:116844
Pharmacological actions of neferine in the modulation of human platelet function.
Yang RP, Zhou YJ, Song W, Yin Z, He AD, Ming ZY
European journal of pharmacology 2019 Nov 5;862:172626
European journal of pharmacology 2019 Nov 5;862:172626
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, Bai Y, Liu Y, Zhao J, Tan B, Luo X, Wang H, Wen L, Zhang C, Zhang H, Ding Y, Qi H, Baker PN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Liu B, Ma H, Liu Q, Xiao Y, Pan S, Zhou H, Jia L
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis.
Liu DW, Zhang YN, Hu HJ, Zhang PQ, Cui W
Molecular medicine reports 2019 Jun;19(6):5335-5344
Molecular medicine reports 2019 Jun;19(6):5335-5344
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Li S, Huang Q, Zhang L, Qiao X, Zhang Y, Tang F, Li Z
European journal of pharmacology 2019 Jun 15;853:1-10
European journal of pharmacology 2019 Jun 15;853:1-10
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
Li W, Wang D, Sun X, Zhang Y, Wang L, Suo J
International journal of molecular medicine 2019 Feb;43(2):914-926
International journal of molecular medicine 2019 Feb;43(2):914-926
Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells.
Zhu L, Wu G, Yang X, Jia X, Li J, Bai X, Li W, Zhao Y, Li Y, Cheng W, Liu S, Jin S
Scientific reports 2019 Feb 28;9(1):3020
Scientific reports 2019 Feb 28;9(1):3020
Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway.
Wei X, Jia Y, Lou H, Ma J, Huang Q, Meng Y, Sun C, Yang Z, Li X, Xu S, Yang X, Ji T, Gao Q
Oncology reports 2019 Dec;42(6):2768-2776
Oncology reports 2019 Dec;42(6):2768-2776
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Yang K, Chen Y, Zhou J, Ma L, Shan Y, Cheng X, Wang Y, Zhang Z, Ji X, Chen L, Dai H, Zhu B, Li C, Tao Z, Hu X, Yin W
British journal of pharmacology 2019 Dec;176(24):4609-4624
British journal of pharmacology 2019 Dec;176(24):4609-4624
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Yang R, Jia Q, Ma SF, Wang Y, Mehmood S, Chen Y
International journal of molecular medicine 2019 Aug;44(2):549-558
International journal of molecular medicine 2019 Aug;44(2):549-558
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, Zhou N, Hao Q, Duan X, Chang Y, Nakai A, Fan Y, Tan K
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2019 Aug 1;424:152236
Toxicology 2019 Aug 1;424:152236
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide promotes bone formation via the canonical Wnt/β-catenin signaling pathway.
Wang T, Sun CH, Zhong HB, Gong Y, Cui ZK, Xie J, Wang YP, Liang C, Cao HH, Chen XR, Zou ZP, Li SF, Bai XC
Phytotherapy research : PTR 2019 Apr;33(4):1074-1083
Phytotherapy research : PTR 2019 Apr;33(4):1074-1083
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
Chen C, Zhou F, Zeng L, Jiang Z, Hu Z
Journal of cellular physiology 2019 Apr;234(4):5304-5318
Journal of cellular physiology 2019 Apr;234(4):5304-5318
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway.
Zheng T, Yang X, Li W, Wang Q, Chen L, Wu D, Bian F, Xing S, Jin S
Oxidative medicine and cellular longevity 2018;2018:8597897
Oxidative medicine and cellular longevity 2018;2018:8597897
Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway.
Yang Y, Sun Y, Xu J, Bao K, Luo M, Liu X, Wang Y
Mediators of inflammation 2018;2018:3685948
Mediators of inflammation 2018;2018:3685948
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, Cheng T, Wang Y, Zhou X, Yang B, Yang GL, Zhang J, Zang X, Ma S, Guan F
Frontiers in cellular neuroscience 2018;12:498
Frontiers in cellular neuroscience 2018;12:498
Elevated GSK3β expression predicts good prognosis in hepatocellular carcinoma.
Hu Y, Lin X, Zuo S, Luo R, Fang W
International journal of clinical and experimental pathology 2018;11(5):2776-2783
International journal of clinical and experimental pathology 2018;11(5):2776-2783
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
Yao R, Sun X, Xie Y, Liu L, Han D, Yao Y, Li H, Li Z, Xu K
American journal of translational research 2018;10(8):2610-2618
American journal of translational research 2018;10(8):2610-2618
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Du Y, Wang L, Chen S, Liu Y, Zhao Y
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Ma L, Gao M, Wu L, Zhao X, Mao H, Xing C
Cell biology international 2018 Sep;42(9):1270-1274
Cell biology international 2018 Sep;42(9):1270-1274
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis.
Song MT, Ruan J, Zhang RY, Deng J, Ma ZQ, Ma SP
Acta pharmacologica Sinica 2018 Oct;39(10):1559-1570
Acta pharmacologica Sinica 2018 Oct;39(10):1559-1570
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Yu B, Wu K, Wang X, Zhang J, Wang L, Jiang Y, Zhu X, Chen W, Yan M
Cell death & disease 2018 Oct 22;9(11):1082
Cell death & disease 2018 Oct 22;9(11):1082
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells.
Xu W, He L, Li Y, Tan Y, Zhang F, Xu H
Bioscience, biotechnology, and biochemistry 2018 Mar;82(3):456-465
Bioscience, biotechnology, and biochemistry 2018 Mar;82(3):456-465
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, Song X, Liu L, Ge W
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Duan X, Meng Q, Wang C, Liu Z, Sun H, Huo X, Sun P, Ma X, Peng J, Liu K
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats.
Liu Z, Li R, Jiang C, Zhao S, Li W, Tang X
European journal of pharmacology 2018 Dec 5;840:50-59
European journal of pharmacology 2018 Dec 5;840:50-59
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Li K, Ma YB, Zhang Z, Tian YH, Xu XL, He YQ, Xu L, Gao Y, Pan WT, Song WJ, He X, Wei L
Cancer medicine 2018 Aug;7(8):3875-3888
Cancer medicine 2018 Aug;7(8):3875-3888
Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice.
Xing F, Yi WJ, Miao F, Su MY, Lei TC
International journal of molecular medicine 2018 Apr;41(4):2079-2085
International journal of molecular medicine 2018 Apr;41(4):2079-2085
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128
Frontiers in molecular neuroscience 2017;10:128
miR-195-5p is critical in REGγ-mediated regulation of wnt/β-catenin pathway in renal cell carcinoma.
Chen S, Wang L, Yao X, Chen H, Xu C, Tong L, Shah A, Huang T, Chen G, Chen J, Liu TL, Li XT, Zheng JH, Li L
Oncotarget 2017 Sep 8;8(38):63986-64000
Oncotarget 2017 Sep 8;8(38):63986-64000
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Song Z, Yang W, Zhou X, Yang L, Zhao D
Neuropharmacology 2017 Sep 1;123:332-348
Neuropharmacology 2017 Sep 1;123:332-348
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y, Liu T, Li L
Experimental dermatology 2017 Nov;26(11):1118-1124
Experimental dermatology 2017 Nov;26(11):1118-1124
Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease.
Guo F, Yi X, Li M, Fu J, Li S
Experimental and therapeutic medicine 2017 Nov;14(5):4231-4237
Experimental and therapeutic medicine 2017 Nov;14(5):4231-4237
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Chengye W, Yu T, Ping S, Deguang S, Keyun W, Yan W, Rixin Z, Rui L, Zhenming G, Mingliang Y, Liming W
Oncotarget 2017 Nov 28;8(61):104247-104257
Oncotarget 2017 Nov 28;8(61):104247-104257
Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients.
Xiang D, Cheng Z, Liu H, Wang X, Han T, Sun W, Li X, Yang W, Chen C, Xia M, Liu N, Yin S, Jin G, Lee T, Dong L, Hu H, Wang H, Ding J
Hepatology (Baltimore, Md.) 2017 May;65(5):1566-1580
Hepatology (Baltimore, Md.) 2017 May;65(5):1566-1580
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
Yuan X, Huang H, Huang Y, Wang J, Yan J, Ding L, Zhang C, Zhang L
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(9):930-938
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(9):930-938
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Li W, Yang X, Zheng T, Xing S, Wu Y, Bian F, Wu G, Li Y, Li J, Bai X, Wu D, Jia X, Wang L, Zhu L, Jin S
Scientific reports 2017 Mar 17;7:44659
Scientific reports 2017 Mar 17;7:44659
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
MicroRNA-500a promotes migration and invasion in hepatocellular carcinoma by activating the Wnt/β-catenin signaling pathway.
Guo Y, Chen L, Sun C, Yu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:13-20
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:13-20
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Yang X, Tang S, Dai C, Li D, Zhang S, Deng S, Zhou Y, Xiao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Jul;105:161-176
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Jul;105:161-176
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Chen S, Sun KX, Feng MX, Sang XB, Liu BL, Zhao Y
Drug design, development and therapy 2016;10:1225-32
Drug design, development and therapy 2016;10:1225-32
Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation.
Zhao Z, Zhang X, Wen L, Yi S, Hu J, Ruan J, Zhao F, Cui G, Fang J, Chen Y
European journal of pharmacology 2016 Oct 15;789:46-59
European journal of pharmacology 2016 Oct 15;789:46-59
Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease.
Zhang Y, Yang X, Jin G, Yang X, Zhang Y
International journal of biological macromolecules 2016 Nov;92:935-941
International journal of biological macromolecules 2016 Nov;92:935-941
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, Yang L, Zhao D
Oncotarget 2016 Mar 15;7(11):12035-52
Oncotarget 2016 Mar 15;7(11):12035-52
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
Wang J, Wan X, Gao Y, Zhong M, Sha L, Liu B, Zhang W, Tian L, Ruan W, Cao S, Huang M
Oncology reports 2016 Jul;36(1):441-7
Oncology reports 2016 Jul;36(1):441-7
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Zhang J, Wen X, Ren XY, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Sun Y, Liu N, Ma J
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway.
Liu Y, Dong M, Yang Z, Pan S
International journal of biological macromolecules 2016 Aug;89:484-8
International journal of biological macromolecules 2016 Aug;89:484-8
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Apr;41(5):1340-9
Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3β and β-catenin.
Pan YY, Deng Y, Xie S, Wang ZH, Wang Y, Ren J, Liu HG
Chinese medical journal 2016 Apr 5;129(7):838-45
Chinese medical journal 2016 Apr 5;129(7):838-45
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859
Scientific reports 2016 Apr 25;6:24859
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a.
Du J, Niu X, Wang Y, Kong L, Wang R, Zhang Y, Zhao S, Nan Y
Scientific reports 2015 Nov 5;5:16163
Scientific reports 2015 Nov 5;5:16163
Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor.
Wang X, Wang M, Li H, Lan X, Liu L, Li J, Li Y, Li J, Yi J, Du X, Yan J, Han Y, Zhang F, Liu M, Lu S, Li D
Molecular and cellular endocrinology 2015 Nov 15;416:57-69
Molecular and cellular endocrinology 2015 Nov 15;416:57-69
RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury.
Hao YQ, Su ZZ, Lv XJ, Li P, Gao P, Wang C, Bai Y, Zhang J
Oncology reports 2015 May;33(5):2438-44
Oncology reports 2015 May;33(5):2438-44
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
Zheng T, Yang X, Wu D, Xing S, Bian F, Li W, Chi J, Bai X, Wu G, Chen X, Zhang Y, Jin S
British journal of pharmacology 2015 Jul;172(13):3284-301
British journal of pharmacology 2015 Jul;172(13):3284-301
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Chen XM, Xie XB, Zhao Q, Wang F, Bai Y, Yin JQ, Jiang H, Xie XL, Jia Q, Huang G
Molecular medicine reports 2015 Jan;11(1):105-12
Molecular medicine reports 2015 Jan;11(1):105-12
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, Li K, Tong L, Gao X, Amjad A, Ji L, Jing T, Jiang Z, Shi K, Yao L, Song D, Liu T, Yang X, Yang C, Cai X, Xu W, Huang Q, He J, Liu J, Chen T, Moses RE, Fu J, Xiao J, Li X
Nature communications 2015 Apr 24;6:6875
Nature communications 2015 Apr 24;6:6875
DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling.
Liu Y, Zhou R, Yuan X, Han N, Zhou S, Xu H, Guo M, Yu S, Zhang C, Yin T, Wu K
Oncotarget 2015 Apr 20;6(11):8621-34
Oncotarget 2015 Apr 20;6(11):8621-34
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.
Masamha CP, Xia Z, Yang J, Albrecht TR, Li M, Shyu AB, Li W, Wagner EJ
Nature 2014 Jun 19;510(7505):412-6
Nature 2014 Jun 19;510(7505):412-6
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Gu GJ, Chen T, Zhou HM, Sun KX, Li J
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Wu Q, He J, Mei W, Zhang Z, Wu X, Sun F
Metallomics : integrated biometal science 2014 Dec;6(12):2204-12
Metallomics : integrated biometal science 2014 Dec;6(12):2204-12
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
Chen XM, Bai Y, Zhong YJ, Xie XL, Long HW, Yang YY, Wu SG, Jia Q, Wang XH
PloS one 2013;8(11):e79201
PloS one 2013;8(11):e79201
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 22104-1-AP(GSK3B antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using GSK3B antibody 22104-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 22104-1-AP(GSK3B antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 22104-1-AP(GSK3B antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
