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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB331P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CXCR2/IL-8RB PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAB25880- Isotype
- IgG
- Antibody clone number
- 48311
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
McDermott DH, De Ravin SS, Jun HS, Liu Q, Priel DA, Noel P, Takemoto CM, Ojode T, Paul SM, Dunsmore KP, Hilligoss D, Marquesen M, Ulrick J, Kuhns DB, Chou JY, Malech HL, Murphy PM
Blood 2010 Oct 14;116(15):2793-802
Blood 2010 Oct 14;116(15):2793-802
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Ahern D, Lloyd CM, Robinson DS
Allergy 2009 Aug;64(8):1121-9
Allergy 2009 Aug;64(8):1121-9
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
Traves SL, Smith SJ, Barnes PJ, Donnelly LE
Journal of leukocyte biology 2004 Aug;76(2):441-50
Journal of leukocyte biology 2004 Aug;76(2):441-50
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Liu LY, Jarjour NN, Busse WW, Kelly EA
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB PE-conjugated Monoclonal Antibody (Catalog # FAB331P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
