CABT-BL7429

antibody from Creative Diagnostics

Targeting: CXCR2 CD182, CMKAR2, IL8RB

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7429

Provider

Creative Diagnostics

Product name

Anti-CXCR3 Monoclonal antibody, clone 6F9-D8-G20

Antibody type

Monoclonal

Description

CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG