Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7429 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-CXCR3 Monoclonal antibody, clone 6F9-D8-G20
- Antibody type
- Monoclonal
- Description
- CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
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