320714

antibody from BioLegend

Targeting: CXCR2 CD182, CMKAR2, IL8RB

Antibody data

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Validation data

Product number: 320714 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#320714, RRID:AB_492940
Product name: Alexa Fluor® 647 anti-human CD182 (CXCR2) [5E8/CXCR2]
Antibody type: Monoclonal
Antigen: Human CXCR2 transfected L1.2 cells
Description: CXCR2 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor B (IL-8RB), CD182, and CD128b. It is a CXC chemokine receptor belongs to G protein-coupled receptor (GPCR) family. CXCR2 is expressed as homodimer or heterodimer with CXCR1 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. CXCR2 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α,β,γ (CXCL1, CXCL2, CXCL3).
Reactivity: Human
Host: Mouse
Conjugate: Red dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CXCR2 protein structure - 320714 shown in red.