Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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- Product number
- NBP2-29460 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CD35 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
- Reactivity
- Human, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
Submitted references FDC:TFH Interactions within Cervical Lymph Nodes of SIV-Infected Rhesus Macaques.
Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients with rheumatoid arthritis.
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Tonsil-derived mesenchymal progenitor cells acquire a follicular dendritic cell phenotype under cytokine stimulation.
Follicular dendritic cells in reactive and neoplastic lymphoid tissues: a reevaluation of staining patterns of CD21, CD23, and CD35 antibodies in paraffin sections after wet heat-induced epitope retrieval.
Dave RS, Sharma RK, Muir RR, Haddad E, Gumber S, Villinger F, Nehra AP, Khan ZK, Wigdahl B, Ansari AA, Byrareddy SN, Jain P
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2018 Jun;13(2):204-218
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2018 Jun;13(2):204-218
Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients with rheumatoid arthritis.
Mokuda S, Doi O, Takasugi K
Modern rheumatology 2012 Sep;22(5):750-7
Modern rheumatology 2012 Sep;22(5):750-7
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Tonsil-derived mesenchymal progenitor cells acquire a follicular dendritic cell phenotype under cytokine stimulation.
Cho KA, Kim JY, Kim HS, Ryu KH, Woo SY
Cytokine 2012 Aug;59(2):211-4
Cytokine 2012 Aug;59(2):211-4
Follicular dendritic cells in reactive and neoplastic lymphoid tissues: a reevaluation of staining patterns of CD21, CD23, and CD35 antibodies in paraffin sections after wet heat-induced epitope retrieval.
Bagdi E, Krenacs L, Krenacs T, Miller K, Isaacson PG
Applied immunohistochemistry & molecular morphology : AIMM 2001 Jun;9(2):117-24
Applied immunohistochemistry & molecular morphology : AIMM 2001 Jun;9(2):117-24
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD35 Antibody (E11) [NBP2-29460] - Formalin-fixed, paraffin-embedded human tonsil stained with CD35 antibody at 1:200 using peroxidase-conjugate and DAB chromogen. Note membrane staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD35 Antibody (E11) [NBP2-29460] - Hhuman Tonsil stained with CD35 Antibody (E11).