Tissue expression
Cell line expression

CR1

gene product
CD35, KN 
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]
More gene data

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
1239 antibodies from 44 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
173 antibodies
NovoPro Bioscience Inc.
3 antibodies
Abgent
3 antibodies
OriGene
26 antibodies
NSJ Bioreagents
4 antibodies
GeneTex
14 antibodies
Invitrogen Antibodies
25 antibodies
Antibodies.com
3 antibodies
Boster Biological Technology
3 antibodies
antibodies-online
429 antibodies
Aviva Systems Biology
9 antibodies
Biorbyt
51 antibodies
HUABIO Research
3 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
LifeSpan BioSciences, Inc.
166 antibodies
Acris Antibodies GmbH
26 antibodies
Arigo
7 antibodies
Abnova Corporation
9 antibodies
Atlas Antibodies
3 antibodies
Santa Cruz Biotechnology
1 antibody
BioLegend
8 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Affinity Biosciences
1 antibody
United States Biological
16 antibodies
Creative Biolabs
89 antibodies
RabMAbs
4 antibodies
MyBioSource
7 antibodies
Leading Biology
11 antibodies
Absolute Antibody
8 antibodies
R&D Systems
9 antibodies
ProSci
2 antibodies
Miltenyi Biotec
26 antibodies
St John's Laboratory
3 antibodies
GenWay
17 antibodies
Abbexa
26 antibodies
Creative Diagnostics
10 antibodies
Abiocode, Inc.
1 antibody
Cell Signaling Technology, Inc
1 antibody
RayBiotech, Inc.
2 antibodies
EMD Millipore
1 antibody
eBioscience, An Affymetrix Company
8 antibodies
Exalpha Biologicals, Inc.
4 antibodies
Abbiotec
1 antibody