60144

antibody from STEMCELL Technologies Inc

Targeting: INPP5D hp51CN, SHIP, SHIP1

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

60144

Provider

STEMCELL Technologies Inc

Product name

Anti-SHIP (C-Terminus) Antibody, Polyclonal

Antibody type

Polyclonal

Description

SHIP (C-terminus) is critical for the function of SHIP protein. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.

Reactivity

Human, Mouse

Vial size

100 µL

Storage

-20°C