Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- AF6868 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Sheep Polyclonal Dystroglycan Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Dystroglycan in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Sheep
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references biAb Mediated Restoration of the Linkage between Dystroglycan and Laminin-211 as a Therapeutic Approach for α-Dystroglycanopathies.
Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice.
Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Gumlaw N, Sevigny LM, Zhao H, Luo Z, Bangari DS, Masterjohn E, Chen Y, McDonald B, Magnay M, Travaline T, Yoshida-Moriguchi T, Fan W, Reczek D, Stefano JE, Qiu H, Beil C, Lange C, Rao E, Lukason M, Barry E, Brondyk WH, Zhu Y, Cheng SH
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):664-676
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):664-676
Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice.
Cataldi MP, Lu P, Blaeser A, Lu QL
Nature communications 2018 Aug 27;9(1):3448
Nature communications 2018 Aug 27;9(1):3448
Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Briggs DC, Yoshida-Moriguchi T, Zheng T, Venzke D, Anderson ME, Strazzulli A, Moracci M, Yu L, Hohenester E, Campbell KP
Nature chemical biology 2016 Oct;12(10):810-4
Nature chemical biology 2016 Oct;12(10):810-4
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Dystroglycan by Western Blot. Detection of Human Dystroglycan by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Dystroglycan in Human Skeletal Muscle. Dystroglycan in Human Skeletal Muscle.