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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- NB600-504 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-504, RRID:AB_10002024
- Product name
- Mouse Monoclonal Aggrecan Antibody
- Antibody type
- Monoclonal
- Description
- Tissue culture supernatant. Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated N-terminal neoepitope ARG after cleavage between amino acids EGE and ARG within the interglobular domain of aggrecanase-catabolised aggrecan.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Feline, Guinea Pig, Porcine, Rabbit, Sheep
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence.
Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system.
The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure.
Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells.
The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration.
17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition.
Extracellular matrix-based cryogels for cartilage tissue engineering.
Immunohistochemical expression and distribution of proteoglycans and collagens in sclerocornea.
Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration.
A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs.
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Si HB, Yang TM, Li L, Tian M, Zhou L, Li DP, Huang Q, Kang PD, Yang J, Zhou ZK, Cheng JQ, Shen B
Molecular therapy. Nucleic acids 2020 Mar 6;19:15-30
Molecular therapy. Nucleic acids 2020 Mar 6;19:15-30
Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system.
Chen L, Liu G, Li W, Wu X
Cellular & molecular biology letters 2019;24:16
Cellular & molecular biology letters 2019;24:16
The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure.
Cheng B, Liu Y, Zhao Y, Li Q, Liu Y, Wang J, Chen Y, Zhang M
Scientific reports 2019 Sep 2;9(1):12642
Scientific reports 2019 Sep 2;9(1):12642
Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells.
Liu Z, Zhang Z, Zhang A, Zhang F, Du W, Zhang Y, Zhang R, Xu J, Wu X, Zhang C, Li N, Tan Q, Huang W
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration.
Jia J, Wang SZ, Ma LY, Yu JB, Guo YD, Wang C
Stem cells international 2018;2018:7162084
Stem cells international 2018;2018:7162084
17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition.
Yang D, Zhu D, Zhu S, Feng F, Gong C, Chen C, Chen L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1004-1009
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1004-1009
Extracellular matrix-based cryogels for cartilage tissue engineering.
Han ME, Kim SH, Kim HD, Yim HG, Bencherif SA, Kim TI, Hwang NS
International journal of biological macromolecules 2016 Dec;93(Pt B):1410-1419
International journal of biological macromolecules 2016 Dec;93(Pt B):1410-1419
Immunohistochemical expression and distribution of proteoglycans and collagens in sclerocornea.
Bouhenni R, Hart M, Al-Jastaneiah S, AlKatan H, Edward DP
International ophthalmology 2013 Dec;33(6):691-700
International ophthalmology 2013 Dec;33(6):691-700
Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration.
Yurube T, Takada T, Suzuki T, Kakutani K, Maeno K, Doita M, Kurosaka M, Nishida K
Arthritis research & therapy 2012 Mar 6;14(2):R51
Arthritis research & therapy 2012 Mar 6;14(2):R51
A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs.
Swearingen CA, Chambers MG, Lin C, Marimuthu J, Rito CJ, Carter QL, Dotzlaf J, Liu C, Chandrasekhar S, Duffin KL, Mitchell PG, Durham TB, Wiley MR, Thirunavukkarasu K
Osteoarthritis and cartilage 2010 Sep;18(9):1159-66
Osteoarthritis and cartilage 2010 Sep;18(9):1159-66
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Little CB, Hughes CE, Curtis CL, Janusz MJ, Bohne R, Wang-Weigand S, Taiwo YO, Mitchell PG, Otterness IG, Flannery CR, Caterson B
Matrix biology : journal of the International Society for Matrix Biology 2002 Apr;21(3):271-88
Matrix biology : journal of the International Society for Matrix Biology 2002 Apr;21(3):271-88
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Little CB, Hughes CE, Curtis CL, Janusz MJ, Bohne R, Wang-Weigand S, Taiwo YO, Mitchell PG, Otterness IG, Flannery CR, Caterson B
Matrix biology : journal of the International Society for Matrix Biology 2002 Apr;21(3):271-88
Matrix biology : journal of the International Society for Matrix Biology 2002 Apr;21(3):271-88
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