ALAS1

gene product
ALAS, ALAS3
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
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253 antibodies from 29 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
antibodies-online
93 antibodies
Novus Biologicals
22 antibodies
Abnova Corporation
4 antibodies
Invitrogen Antibodies
3 antibodies
Biorbyt
19 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
22 antibodies
OriGene
9 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
3 antibodies
St John's Laboratory
3 antibodies
Abgent
3 antibodies
GeneTex
3 antibodies
Boster Biological Technology
2 antibodies
Abbexa
1 antibody
Acris Antibodies GmbH
2 antibodies
ABEOMICS Inc.
2 antibodies
Aviva Systems Biology
2 antibodies
ProSci
2 antibodies
MyBioSource
2 antibodies
United States Biological
28 antibodies
Creative Biolabs
5 antibodies
Creative Diagnostics
3 antibodies
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
2 antibodies