ABIN493258

antibody from antibodies-online

Targeting: PDE4A DPDE2

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN493258

Provider

antibodies-online

Product name

anti-phosphodiesterase 4A, CAMP-Specific (PDE4A) (N-Term) antibody

Antibody type

Polyclonal

Antigen

N-terminus PDE4A5 synthetic cyclic peptide

Description

Affinity chromatography

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

0.1 mg

Concentration

1.0 - 1.25 mg/mL

Storage

Store (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.

MacKenzie SJ, Houslay MD
The Biochemical journal 2000 Apr 15;347(Pt 2):571-8

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The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions.

Houslay MD, Sullivan M, Bolger GB
Advances in pharmacology (San Diego, Calif.) 1998;44:225-342

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Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2.

Sullivan M, Rena G, Begg F, Gordon L, Olsen AS, Houslay MD
The Biochemical journal 1998 Aug 1;333 ( Pt 3):693-703