Tissue expression
Cell line expression
Protein structure
PDE4A
Phosphodiesterase 4ADPDE2
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
Top validated antibodies |
|||||
Invitrogen Antibodies | 16226-1-AP | Polyclonal |
WB
IP
IHC
FC
OA
|
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Proteintech Group | 16226-1-AP | Polyclonal |
WB
EL
IP
IHC
FC
|
||
GeneTex | GTX14606 | 2 references | Polyclonal |
WB
ICC
IP
|
|
OriGene | TA501153 | Monoclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider