Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [2]
- Other assay [1]
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Validation data
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- Product number
- MA1-19596 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD41 Monoclonal Antibody (MEM-06), FITC
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This antibody reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- MEM-06
- Vial size
- 100 Tests
- Storage
- 4° C, store in dark, DO NOT FREEZE!
Submitted references Downregulation of Long Non-coding RNA Nuclear Paraspeckle Assembly Transcript 1 Inhibits MEG-01 Differentiation and Platelet-Like Particles Activity.
Bian W, Chen W, Jiang X, Qu H, Jiang J, Yang J, Liang X, Zhao B, Sun Y, Zhang C
Frontiers in genetics 2020;11:571467
Frontiers in genetics 2020;11:571467
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC Monoclonal antibody (Product # MA1-19596) using a dilution of 20 µL reagent/100 µL of peripheral whole blood.
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of human CD41 positive thrombocytes (red-filled) from CD41 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC Monoclonal antibody (Product # MA1-19596) using a dilution of 20 µL reagent/100 µL of peripheral whole blood.
- Conjugate
- Green dye
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 5 NEAT1 knockdown decreases CD41 and CD42b expression on MEG-01 cells. MEG-01 cells were transfected with siCTRL or siNEAT1 and were incubated with FITC-anti-CD41 and PE-anti-CD42b. (A) The CD41 and CD42b-positive PLPs were detected by flow cytometry. The images were representative of three independent experiments ( n = 3). (B) The percentage of the upper right quadrant was used to calculate the differentiation rate ( n = 3, * p < 0.05 vs. siCTRL).
- Conjugate
- Green dye