ITGA2B

gene product
CD41, CD41B, GP2B, PPP1R93
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
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1688 antibodies from 45 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
32 antibodies
antibodies-online
561 antibodies
Biorbyt
90 antibodies
Novus Biologicals
159 antibodies
Antibodies.com
12 antibodies
LifeSpan BioSciences, Inc.
242 antibodies