ITGA2B

gene product
CD41, CD41B, GP2B, PPP1R93
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
974 antibodies from 38 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
31 antibodies
antibodies-online
264 antibodies
Biorbyt
53 antibodies
Novus Biologicals
164 antibodies
NovoPro Bioscience Inc.
4 antibodies
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
34 antibodies
Proteintech Group
2 antibodies
Abnova Corporation
22 antibodies
Invitrogen Antibodies
19 antibodies
OriGene
23 antibodies
BioLegend
48 antibodies
Aviva Systems Biology
15 antibodies
R&D Systems
6 antibodies
Atlas Antibodies
4 antibodies
NSJ Bioreagents
2 antibodies
LifeSpan BioSciences, Inc.
135 antibodies
Abbiotec
6 antibodies