Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- GTX76011 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX76011, RRID:AB_378503
- Product name
- CD41 antibody [MWReg30]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse
- Host
- Rat
Submitted references Loss of the mitochondrial kinase PINK1 does not alter platelet function.
Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity in multiple myeloma bone disease.
Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation.
Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging.
Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets.
A novel hollow and perforated flexible wire allows the safe and effective local application of thrombolytic therapy in a mouse model of deep vein thrombosis.
Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.
Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2.
Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer.
Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.
In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice.
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody.
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
Walsh TG, van den Bosch MTJ, Lewis KE, Williams CM, Poole AW
Scientific reports 2018 Sep 26;8(1):14377
Scientific reports 2018 Sep 26;8(1):14377
Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity in multiple myeloma bone disease.
Muller J, Bolomsky A, Dubois S, Duray E, Stangelberger K, Plougonven E, Lejeune M, Léonard A, Marty C, Hempel U, Baron F, Beguin Y, Cohen-Solal M, Ludwig H, Heusschen R, Caers J
Haematologica 2018 Aug;103(8):1359-1368
Haematologica 2018 Aug;103(8):1359-1368
Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.
Günther F, Heidt T, Kramer M, Khanicheh E, Klibanov AL, Geibel-Zehender A, Ferrante EA, Hilgendorf I, Wolf D, Zirlik A, Reinöhl J, Bode C, Peter K, Kaufmann BA, Mühlen CVZ
Scientific reports 2017 Nov 2;7(1):14898
Scientific reports 2017 Nov 2;7(1):14898
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation.
Miyata K, Takemoto A, Okumura S, Nishio M, Fujita N
Scientific reports 2017 Jun 22;7(1):4059
Scientific reports 2017 Jun 22;7(1):4059
Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging.
Heidt T, Ehrismann S, Hövener JB, Neudorfer I, Hilgendorf I, Reisert M, Hagemeyer CE, Zirlik A, Reinöhl J, Bode C, Peter K, von Elverfeldt D, von Zur Muhlen C
Scientific reports 2016 May 3;6:25044
Scientific reports 2016 May 3;6:25044
Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets.
Ziegler M, Alt K, Paterson BM, Kanellakis P, Bobik A, Donnelly PS, Hagemeyer CE, Peter K
Scientific reports 2016 Dec 2;6:38161
Scientific reports 2016 Dec 2;6:38161
A novel hollow and perforated flexible wire allows the safe and effective local application of thrombolytic therapy in a mouse model of deep vein thrombosis.
Witsch T, Mauler M, Herr N, Stallmann D, Bode C, Hehrlein C, Duerschmied D
Journal of thrombosis and thrombolysis 2014 May;37(4):450-4
Journal of thrombosis and thrombolysis 2014 May;37(4):450-4
Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.
von Elverfeldt D, Maier A, Duerschmied D, Braig M, Witsch T, Wang X, Mauler M, Neudorfer I, Menza M, Idzko M, Zirlik A, Heidt T, Bronsert P, Bode C, Peter K, von Zur Muhlen C
Circulation 2014 Aug 19;130(8):676-87
Circulation 2014 Aug 19;130(8):676-87
Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2.
Takagi S, Sato S, Oh-hara T, Takami M, Koike S, Mishima Y, Hatake K, Fujita N
PloS one 2013;8(8):e73609
PloS one 2013;8(8):e73609
Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer.
Weibel S, Hofmann E, Basse-Luesebrink TC, Donat U, Seubert C, Adelfinger M, Gnamlin P, Kober C, Frentzen A, Gentschev I, Jakob PM, Szalay AA
Journal of translational medicine 2013 May 1;11:106
Journal of translational medicine 2013 May 1;11:106
Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.
Guenther F, Herr N, Mauler M, Witsch T, Roming F, Hein L, Boeynaems JM, Robaye B, Idzko M, Bode C, Von Zur Muhlen C, Duerschmied D
Journal of thrombosis and haemostasis : JTH 2013 Jun;11(6):1154-62
Journal of thrombosis and haemostasis : JTH 2013 Jun;11(6):1154-62
In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice.
von Elverfeldt D, von zur Muhlen C, Wiens K, Neudorfer I, Zirlik A, Meissner M, Tilly P, Charles AL, Bode C, Peter K, Fabre JE
PloS one 2012;7(9):e45008
PloS one 2012;7(9):e45008
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody.
Heidt T, Deininger F, Peter K, Goldschmidt J, Pethe A, Hagemeyer CE, Neudorfer I, Zirlik A, Weber WA, Bode C, Meyer PT, Behe M, von Zur Mühlen C
PloS one 2011 Mar 30;6(3):e18446
PloS one 2011 Mar 30;6(3):e18446
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
von zur Muhlen C, von Elverfeldt D, Moeller JA, Choudhury RP, Paul D, Hagemeyer CE, Olschewski M, Becker A, Neudorfer I, Bassler N, Schwarz M, Bode C, Peter K
Circulation 2008 Jul 15;118(3):258-67
Circulation 2008 Jul 15;118(3):258-67
No comments: Submit comment
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of mouse peripheral blood with Rat anti-Mouse CD41 (GTX76011). Platelets stain strongly for CD41