Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7863 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-ITGA2B Monoclonal antibody, clone NXSfh40
- Antibody type
- Monoclonal
- Description
- ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
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