Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 24552-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CD41/Integrin Alpha 2B antibody
- Antibody type
- Polyclonal
- Description
- CD41/Integrin Alpha 2B antibody (Cat. #24552-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model.
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Integrin Alpha-2 as a Potential Prognostic and Predictive Biomarker for Patients With Lower-Grade Glioma.
Biomimetic Platform Based on Mesoporous Platinum for Multisynergistic Cancer Therapy.
DMAG, a novel countermeasure for the treatment of thrombocytopenia.
Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.
Low arterial oxygen partial pressure induces pulmonary thrombocytopenia in patients and a mouse model.
MicroRNA-155-5p promotes tumor progression and contributes to paclitaxel resistance via TP53INP1 in human breast cancer.
Platelet-derived porous nanomotor for thrombus therapy.
Cangrelor alleviates bleomycin-induced pulmonary fibrosis by inhibiting platelet activation in mice.
The role of necroptosis and apoptosis through the oxidative stress pathway in the liver of selenium-deficient swine.
Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation.
RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway.
Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy.
Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors.
Takauji S, Tanaka H, Hayakawa M, Horioka K, Isozaki S, Konishi H
Biochemical and biophysical research communications 2022 Jan 8;587:1-8
Biochemical and biophysical research communications 2022 Jan 8;587:1-8
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Chen X, Wang C, Sun N, Pan S, Li R, Li X, Zhao J, Tong H, Tang Y, Han J, Qiao J, Qiu H, Wang H, Yang J, Ikezoe T
Theranostics 2021;11(10):4655-4671
Theranostics 2021;11(10):4655-4671
Integrin Alpha-2 as a Potential Prognostic and Predictive Biomarker for Patients With Lower-Grade Glioma.
Lin L, Huang K, Tu Z, Zhu X, Li J, Lei K, Luo M, Wang P, Gong C, Long X, Wu L
Frontiers in oncology 2021;11:738651
Frontiers in oncology 2021;11:738651
Biomimetic Platform Based on Mesoporous Platinum for Multisynergistic Cancer Therapy.
Zhao G, Li J, Fangfang Lv, Wang X, Dong Q, Liu D, Zhang J, Li Z, Zhou X, Liu H
ACS biomaterials science & engineering 2021 Nov 8;7(11):5154-5164
ACS biomaterials science & engineering 2021 Nov 8;7(11):5154-5164
DMAG, a novel countermeasure for the treatment of thrombocytopenia.
Lin J, Zeng J, Liu S, Shen X, Jiang N, Wu YS, Li H, Wang L, Wu JM
Molecular medicine (Cambridge, Mass.) 2021 Nov 27;27(1):149
Molecular medicine (Cambridge, Mass.) 2021 Nov 27;27(1):149
Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.
Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X, Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C
eLife 2021 Jun 10;10
eLife 2021 Jun 10;10
Low arterial oxygen partial pressure induces pulmonary thrombocytopenia in patients and a mouse model.
Wu L, Guo N, Xu Z, Wang W, Xiong Q, Hu J, Wan R, Hong K
BMC pulmonary medicine 2021 Jan 6;21(1):3
BMC pulmonary medicine 2021 Jan 6;21(1):3
MicroRNA-155-5p promotes tumor progression and contributes to paclitaxel resistance via TP53INP1 in human breast cancer.
Li Y, Zhang L, Dong Z, Xu H, Yan L, Wang W, Yang Q, Chen C
Pathology, research and practice 2021 Apr;220:153405
Pathology, research and practice 2021 Apr;220:153405
Platelet-derived porous nanomotor for thrombus therapy.
Wan M, Wang Q, Wang R, Wu R, Li T, Fang D, Huang Y, Yu Y, Fang L, Wang X, Zhang Y, Miao Z, Zhao B, Wang F, Mao C, Jiang Q, Xu X, Shi D
Science advances 2020 May;6(22):eaaz9014
Science advances 2020 May;6(22):eaaz9014
Cangrelor alleviates bleomycin-induced pulmonary fibrosis by inhibiting platelet activation in mice.
Zhan T, Wei T, Dong L, Wang Q, Wu Z, Yan Q, Zhang W, Lu Y, Wu M
Molecular immunology 2020 Apr;120:83-92
Molecular immunology 2020 Apr;120:83-92
The role of necroptosis and apoptosis through the oxidative stress pathway in the liver of selenium-deficient swine.
Zhang Y, Yu D, Zhang J, Bao J, Tang C, Zhang Z
Metallomics : integrated biometal science 2020 Apr 1;12(4):607-616
Metallomics : integrated biometal science 2020 Apr 1;12(4):607-616
Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation.
Su C, Wang Q, Zhang H, Jiao W, Luo H, Li L, Chen X, Liu B, Yu X, Li S, Wang W, Guo S
Frontiers in pharmacology 2019;10:990
Frontiers in pharmacology 2019;10:990
RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway.
Shi Y, Yu J, Zhang Y, Zhao B, Li Y, Ye Y, Yu Q, Yu M, Mo W, Gu J
Biochemical pharmacology 2019 Nov;169:113634
Biochemical pharmacology 2019 Nov;169:113634
Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy.
Sun Y, Dai H, Chen S, Zhang Y, Wu T, Cao X, Zhao G, Xu A, Wang J, Wu L
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Oct 3;26(10):2456-2465
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Oct 3;26(10):2456-2465
Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors.
Luo Q, Wei G, Wu X, Tang K, Xu M, Wu Y, Liu Y, Li X, Sun Z, Ju W, Qi K, Chen C, Yan Z, Cheng H, Zhu F, Li Z, Zeng L, Xu K, Qiao J
Journal of translational medicine 2018 Nov 15;16(1):311
Journal of translational medicine 2018 Nov 15;16(1):311
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human blood tissue were subjected to SDS PAGE followed by western blot with 24552-1-AP( ITGA2B Antibody) at dilution of 1:3000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD41/Integrin alpha 2b antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CD41/Integrin alpha 2b. This antibody recognizes human antigen. The CD41/Integrin alpha 2b antibody has been validated for the following applications: ELISA, WB, IHC analysis.