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LearnPAB4911
antibody from Abnova Corporation
Targeting: LRP1
A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PAB4911 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4911, RRID:AB_1577971
- Product name
- LRP1 (phospho S4520) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of LRP1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner.
Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone.
Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
Yu G, Rux AH, Ma P, Bdeir K, Sachais BS
Blood 2005 May 1;105(9):3545-51
Blood 2005 May 1;105(9):3545-51
Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone.
Niemeier A, Kassem M, Toedter K, Wendt D, Ruether W, Beisiegel U, Heeren J
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Feb;20(2):283-93
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Feb;20(2):283-93
Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
Cam JA, Zerbinatti CV, Li Y, Bu G
The Journal of biological chemistry 2005 Apr 15;280(15):15464-70
The Journal of biological chemistry 2005 Apr 15;280(15):15464-70
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with LRP1 (phospho S452) polyclonal antibody (Cat # PAB4911) which was peroxidase-conjugated to the secondary antibody followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Dot blot analysis of LRP1 (phospho S452) polyclonal antibody (Cat # PAB4911) on nitrocellulose membrane. 50 ng of phospho-peptide or non phospho-peptide per dot were adsorbed. Antobodies working concentration was 0.5 ug per mL.
- Validation comment
- Dot Blot (Peptide)
