Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00001543-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00001543-B01P, RRID:AB_11019443
- Product name
- Mouse Polyclonal Cytochrome P450 1A1 Antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models.
Inhibition of β-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
Zapletal O, Tylichová Z, Neča J, Kohoutek J, Machala M, Milcová A, Pokorná M, Topinka J, Moyer MP, Hofmanová J, Kozubík A, Vondráček J
Archives of toxicology 2017 May;91(5):2135-2150
Archives of toxicology 2017 May;91(5):2135-2150
Inhibition of β-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
Kabátková M, Zapletal O, Tylichová Z, Neča J, Machala M, Milcová A, Topinka J, Kozubík A, Vondráček J
Mutagenesis 2015 Jul;30(4):565-76
Mutagenesis 2015 Jul;30(4):565-76
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Western Blot: Cytochrome P450 1A1 Antibody [H00001543-B01P] - Analysis of CYP1A1 expression in transfected 293T cell line by CYP1A1 polyclonal antibody. Lane 1: CYP1A1 transfected lysate(56.32 KDa). Lane 2: Non-transfected lysate.