CYP1A1

gene product
CP11, CYP1, P1-450, P450-C, P450DX
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
507 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
antibodies-online
161 antibodies
Novus Biologicals
8 antibodies
GeneTex
8 antibodies
Invitrogen Antibodies
5 antibodies
Biorbyt
32 antibodies
OriGene
17 antibodies
LifeSpan BioSciences, Inc.
103 antibodies
NSJ Bioreagents
6 antibodies
Abnova Corporation
6 antibodies
Acris Antibodies GmbH
12 antibodies
Abgent
7 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
4 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Aviva Systems Biology
9 antibodies
Santa Cruz Biotechnology
1 antibody
ProSci
6 antibodies
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
4 antibodies
Creative Diagnostics
9 antibodies
Bioss
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RabMAbs
2 antibodies
Creative Biolabs
10 antibodies
MyBioSource
14 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
43 antibodies
Enzo Life Sciences
8 antibodies
EMD Millipore
6 antibodies
Leading Biology
6 antibodies
GenWay
3 antibodies
Sigma-Aldrich
2 antibodies