ANAPC2

gene product
APC2, KIAA1406
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
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MyBioSource
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Abnova Corporation
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Abgent
1 antibody
Atlas Antibodies
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Creative Diagnostics
1 antibody
ProSci
1 antibody
GeneTex
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GenWay
1 antibody
Leading Biology
1 antibody
St John's Laboratory
1 antibody
United States Biological
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Sigma-Aldrich
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