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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- MAB22591 - Provider product page
- Provider
- R&D Systems
- Product name
- Insect Cathepsin L Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects pro and mature forms of Insect Cathepsin L in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant human Cathepsin L is observed and no cross-reactivity with recombinant mouse Cathepsin L is observed.
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 193702
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome.
The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.
Characterization of cathepsin L secreted by Sf21 insect cells.
Şentürk M, Lin G, Zuo Z, Mao D, Watson E, Mikos AG, Bellen HJ
Nature cell biology 2019 Mar;21(3):384-396
Nature cell biology 2019 Mar;21(3):384-396
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.
Mao D, Lin G, Tepe B, Zuo Z, Tan KL, Senturk M, Zhang S, Arenkiel BR, Sardiello M, Bellen HJ
Autophagy 2019 Jul;15(7):1214-1233
Autophagy 2019 Jul;15(7):1214-1233
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome.
Li C, Brazill JM, Liu S, Bello C, Zhu Y, Morimoto M, Cascio L, Pauly R, Diaz-Perez Z, Malicdan MCV, Wang H, Boccuto L, Schwartz CE, Gahl WA, Boerkoel CF, Zhai RG
Nature communications 2017 Nov 2;8(1):1257
Nature communications 2017 Nov 2;8(1):1257
The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.
Luan S, Ilvarsonn AM, Eissenberg JC
PloS one 2012;7(9):e45163
PloS one 2012;7(9):e45163
Characterization of cathepsin L secreted by Sf21 insect cells.
Johnson GD, Jiang W
Archives of biochemistry and biophysics 2005 Dec 1;444(1):7-14
Archives of biochemistry and biophysics 2005 Dec 1;444(1):7-14
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