CTSL

gene product
CTSL1, FLJ31037
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
418 antibodies from 33 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
R&D Systems
9 antibodies
antibodies-online
115 antibodies
Enzo Life Sciences
4 antibodies
Novus Biologicals
57 antibodies
GeneTex
10 antibodies
LifeSpan BioSciences, Inc.
103 antibodies
Acris Antibodies GmbH
7 antibodies
OriGene
16 antibodies
Abnova Corporation
8 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
8 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
NovoPro Bioscience Inc.
5 antibodies
Biorbyt
19 antibodies
RabMAbs
2 antibodies
Aviva Systems Biology
3 antibodies
Arigo
1 antibody
Creative Diagnostics
3 antibodies
Bioworld Technology, Inc
1 antibody
ProSci
1 antibody
Creative Biolabs
6 antibodies
St John's Laboratory
4 antibodies
MyBioSource
9 antibodies
RayBiotech, Inc.
4 antibodies
Boster Biological Technology
2 antibodies
Abbiotec
1 antibody
Sigma-Aldrich
3 antibodies
eBioscience, An Affymetrix Company
4 antibodies
Abgent
4 antibodies
NSJ Bioreagents
1 antibody
United States Biological
1 antibody
Abbexa
3 antibodies
GenWay
1 antibody