27952-1-AP

antibody from Proteintech Group

Targeting: CTSL CTSL1, FLJ31037

Provider product page for 27952-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [15]
Comments [0]
Validations [0]

Submit

Product number: 27952-1-AP - Provider product page
Provider: Proteintech Group
Product name: Cathepsin L antibody
Antibody type: Polyclonal
Description: KD/KO validated Cathepsin L antibody (Cat. #27952-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CTSL protein structure - 27952-1-AP shown in red.

Submitted references Integration of Single-cell and Bulk Transcriptome Analyses Unravels a Macrophage-based Gene Signature for Prognostication and Treatment in Triple-negative Breast Cancer.

Huang Y, Yu Y, Zhu Y, Lu Q, Zhang Z, Wang X, Wang X, Zheng Y
International journal of medical sciences 2026;23(1):253-270

TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice.

Khan S, Yan F, Li W, Guo J, Gu X, Tang Z, Bibi U, Dong X, Chen L, Yao Y, Xu J
Journal of translational medicine 2026 Mar 17;24(1)

A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapy.

You Q, Wu G, Li H, Liu J, Cao F, Ding L, Liang F, Zhou B, Ma L, Zhu L, Wang C, Yang Y, Chen X
Nature nanotechnology 2025 Sep;20(9):1298-1311

Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.

Liu R, Chen Y, Huang H, Li X, Lv J, Jiang L, Jiang H, Wu C, Chen W, Xu H, Zhu Z, Cai H, Xiao J, Yin L, Ni W
British journal of pharmacology 2025 Nov;182(22):5489-5516

USP20 competitively binds to STUB1 to enhance CTSL expression and promote epithelial-mesenchymal transition in head and neck squamous cell carcinoma.

Guo L, Zhang B, Cui X, Wang X, Xiao J, Miao S, Song K, Sun J
Clinical and translational medicine 2025 Nov;15(11):e70520

Anti-sarcopenic effects of active vitamin D through modulation of anabolic and catabolic signaling pathways in human skeletal muscle: A randomized controlled trial.

Kawahara T, Inazu T, Mizuno S, Tominaga N, Toda M, Toyama N, Kawahara C, Suzuki G, DPVD Research Group
Metabolism: clinical and experimental 2025 Jul;168:156240

Design, Synthesis, and Biological Evaluation of 2-Arylaminopyrimidine Derivatives as Dual Cathepsin L and JAK Inhibitors for the Treatment of Acute Lung Injury.

Shen C, Mao Z, Chen T, Wei Y, Zhou T, Zhong N, Zhu G, Shi Q, Xie Z, Zhao H, Zhang X
Journal of medicinal chemistry 2025 Jan 9;68(1):361-386

CTSL Promotes Autophagy in Laryngeal Cancer Through the IL6-JAK-STAT3 Signalling Pathway.

Wang X, Wang J, Wang L, Song M, Meng H, Guo E, Miao S
Journal of cellular and molecular medicine 2025 Feb;29(3):e70364

The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells.

Sui M, Liu T, Song X, Li J, Ding H, Liu Y, Wang X, Liu H, Xue Y, Qi J, Zhang M, Zhao S, Zhu Q
Pharmacological research 2025 Feb;212:107619

Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier.

Chen Y, Zhou Y, Bai Y, Jia K, Zhang H, Chen Q, Song M, Dai Y, Shi J, Chen Z, Yan X, Shen Y
Neuron 2025 Apr 2;113(7):1082-1097.e8

Alumina nanoparticles induce learning and memory impairment in a particle size-dependent and time-dependent manner.

Zhang Y, Jia L, Wang Z, Guo W, Qin X, Ge C, Niu Q, Zhang Q
Ecotoxicology and environmental safety 2025 Apr 15;295:118177

Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer.

Xiao LX, Li XJ, Yu HY, Qiu RJ, Zhai ZY, Ding WF, Zhu MS, Zhong W, Fang CF, Yang J, Chen T, Yu J
World journal of gastroenterology 2024 Dec 21;30(47):5032-5054

Liu Z, Zeinalzadeh Z, Huang T, Han Y, Peng L, Wang D, Zhou Z, Ousmane D, Wang J
Translational oncology 2024 Apr;42:101896

Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.

Li ZB, Jiang L, Ni JD, Xu YH, Liu F, Liu WM, Wang SG, Liu ZQ, Wang CY
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205

Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.

Fan H, Hao X, Gao Y, Yang J, Liu A, Su Y, Xia Y
Frontiers in pharmacology 2022;13:943272

No comments: Submit comment

No validations: Submit validation data