Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10750-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10750-1-AP, RRID:AB_2272729
- Product name
- UCP3 antibody
- Antibody type
- Polyclonal
- Description
- UCP3 antibody (Cat. #10750-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice.
β-Hydroxy-β-methyl Butyrate Regulates the Lipid Metabolism, Mitochondrial Function, and Fat Browning of Adipocytes.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Exposure to melamine cyanuric acid in adult mice caused motor activity and skeletal muscle energy metabolism disorder.
BMP10 positively regulates myogenic differentiation in C2C12 myoblasts via the Smad 1/5/8 signaling pathway.
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
PPARδ Attenuates Alcohol-Mediated Insulin Resistance by Enhancing Fatty Acid-Induced Mitochondrial Uncoupling and Antioxidant Defense in Skeletal Muscle.
DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1.
Ischemic postconditioning reduced myocardial ischemia-reperfusion injury: The roles of melatonin and uncoupling protein 3.
Insulin-like growth factor-1 directly mediates expression of mitochondrial uncoupling protein 3 via forkhead box O4.
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.
Nakanishi R, Tanaka M, Nisa BU, Shimizu S, Hirabayashi T, Tanaka M, Maeshige N, Roy RR, Fujino H
PloS one 2023;18(11):e0289086
PloS one 2023;18(11):e0289086
β-Hydroxy-β-methyl Butyrate Regulates the Lipid Metabolism, Mitochondrial Function, and Fat Browning of Adipocytes.
Duan G, Zheng C, Yu J, Zhang P, Wan M, Zheng J, Duan Y
Nutrients 2023 May 30;15(11)
Nutrients 2023 May 30;15(11)
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Son JS, Chae SA, Zhao L, Wang H, de Avila JM, Zhu MJ, Jiang Z, Du M
EBioMedicine 2022 Feb;76:103842
EBioMedicine 2022 Feb;76:103842
Exposure to melamine cyanuric acid in adult mice caused motor activity and skeletal muscle energy metabolism disorder.
Wang S, Zuo X, Xu B, Yu Q, An Z, Feng D, Feng X
Physiology & behavior 2022 Dec 1;257:113990
Physiology & behavior 2022 Dec 1;257:113990
BMP10 positively regulates myogenic differentiation in C2C12 myoblasts via the Smad 1/5/8 signaling pathway.
Dang TTH, Yun JW
Molecular and cellular biochemistry 2021 May;476(5):2085-2097
Molecular and cellular biochemistry 2021 May;476(5):2085-2097
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
Zheng X, Liu D
Life sciences 2021 Jan 15;265:118825
Life sciences 2021 Jan 15;265:118825
PPARδ Attenuates Alcohol-Mediated Insulin Resistance by Enhancing Fatty Acid-Induced Mitochondrial Uncoupling and Antioxidant Defense in Skeletal Muscle.
Koh JH, Kim KH, Park SY, Kim YW, Kim JY
Frontiers in physiology 2020;11:749
Frontiers in physiology 2020;11:749
DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1.
Hong Z, Zhang W, Ding D, Huang Z, Yan Y, Cao W, Pan Y, Hou X, Weroha SJ, Karnes RJ, Wang D, Wu Q, Wu D, Huang H
Molecular cell 2020 Sep 17;79(6):1008-1023.e4
Molecular cell 2020 Sep 17;79(6):1008-1023.e4
Ischemic postconditioning reduced myocardial ischemia-reperfusion injury: The roles of melatonin and uncoupling protein 3.
Aslan G, Gül HF, Tektemur A, Sahna E
Anatolian journal of cardiology 2020 Jan;23(1):19-27
Anatolian journal of cardiology 2020 Jan;23(1):19-27
Insulin-like growth factor-1 directly mediates expression of mitochondrial uncoupling protein 3 via forkhead box O4.
Watamoto Y, Futawaka K, Hayashi M, Matsushita M, Mitsutani M, Murakami K, Song Z, Koyama R, Fukuda Y, Nushida A, Nezu S, Kuwahara A, Kataoka K, Tagami T, Moriyama K
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2019 Jun-Aug;46-47:24-35
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2019 Jun-Aug;46-47:24-35
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
Koentges C, Cimolai MC, Pfeil K, Wolf D, Marchini T, Tarkhnishvili A, Hoffmann MM, Odening KE, Diehl P, von Zur Mühlen C, Alvarez S, Bode C, Zirlik A, Bugger H
Journal of molecular and cellular cardiology 2019 Aug;133:138-147
Journal of molecular and cellular cardiology 2019 Aug;133:138-147
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Chen Y, Chang Y, Zhang N, Guo X, Sun G, Sun Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
Rodríguez-Hidalgo M, Luna-Sánchez M, Hidalgo-Gutiérrez A, Barriocanal-Casado E, Mascaraque C, Acuña-Castroviejo D, Rivera M, Escames G, López LC
Scientific reports 2018 Sep 18;8(1):14013
Scientific reports 2018 Sep 18;8(1):14013
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.
Dromparis P, Paulin R, Sutendra G, Qi AC, Bonnet S, Michelakis ED
Circulation research 2013 Jul 5;113(2):126-36
Circulation research 2013 Jul 5;113(2):126-36
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 10750-1-AP(UCP3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UCP3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human UCP3. This antibody recognizes human, mouse, rat antigen. The UCP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
