Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 11194-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11194-1-AP, RRID:AB_2224414
- Product name
- AKR1C3 antibody
- Antibody type
- Polyclonal
- Description
- AKR1C3 antibody (Cat. #11194-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mangiferin alleviates 6-OHDA-induced Parkinson's disease by inhibiting AKR1C3 to activate Wnt signaling pathway.
Possible New Histological Prognostic Index for Large B-Cell Lymphoma.
Prostaglandin F(2α) synthase promotes oxaliplatin resistance in colorectal cancer through prostaglandin F(2α)-dependent and F(2α)-independent mechanism.
Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer.
Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia.
AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer.
15-Deoxy-Δ(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines.
Huang W, Wang Y, Huang W
Neuroscience letters 2024 Jan 31;821:137608
Neuroscience letters 2024 Jan 31;821:137608
Possible New Histological Prognostic Index for Large B-Cell Lymphoma.
Nitta H, Takizawa H, Mitsumori T, Iizuka-Honma H, Araki Y, Fujishiro M, Tomita S, Kishikawa S, Hashizume A, Sawada T, Okubo M, Sekiguchi Y, Ando M, Noguchi M
Journal of clinical medicine 2023 Sep 30;12(19)
Journal of clinical medicine 2023 Sep 30;12(19)
Prostaglandin F(2α) synthase promotes oxaliplatin resistance in colorectal cancer through prostaglandin F(2α)-dependent and F(2α)-independent mechanism.
Wang YJ, Xie XL, Liu HQ, Tian H, Jiang XY, Zhang JN, Chen SX, Liu T, Wang SL, Zhou X, Jin XX, Liu SM, Jiang HQ
World journal of gastroenterology 2023 Oct 21;29(39):5452-5470
World journal of gastroenterology 2023 Oct 21;29(39):5452-5470
Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer.
Liu Y, Chen Y, Jiang J, Chu X, Guo Q, Zhao L, Feng F, Liu W, Zhang X, He S, Yang P, Fang P, Sun H
European journal of medicinal chemistry 2023 Feb 5;247:115013
European journal of medicinal chemistry 2023 Feb 5;247:115013
Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia.
Blaize JL, Noori BM, Hunter KP, Henrikson KA, Atoyan JA, Ardito AA, Donovan FX, Chandrasekharappa SC, Schindler D, Howlett NG
bioRxiv : the preprint server for biology 2023 Apr 27;
bioRxiv : the preprint server for biology 2023 Apr 27;
AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer.
Liu C, Yang JC, Armstrong CM, Lou W, Liu L, Qiu X, Zou B, Lombard AP, D'Abronzo LS, Evans CP, Gao AC
Molecular cancer therapeutics 2019 Oct;18(10):1875-1886
Molecular cancer therapeutics 2019 Oct;18(10):1875-1886
15-Deoxy-Δ(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines.
Li H, Narahara H
International journal of molecular medicine 2013 Apr;31(4):778-88
International journal of molecular medicine 2013 Apr;31(4):778-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 11194-1-AP(AKR1C3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11194-1-AP(AKR1C3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKR1C3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKR1C3. This antibody recognizes human antigen. The AKR1C3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.