AKR1C3

gene product
DDX, HAKRB, HSD17B5, KIAA0119, PGFS
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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366 antibodies from 33 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
GeneTex
4 antibodies
R&D Systems
2 antibodies
antibodies-online
135 antibodies
Invitrogen Antibodies
5 antibodies
Proteintech Group
1 antibody
Biorbyt
17 antibodies
NovoPro Bioscience Inc.
4 antibodies
Abnova Corporation
7 antibodies
Abgent
3 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
55 antibodies
Acris Antibodies GmbH
6 antibodies
St John's Laboratory
4 antibodies
OriGene
6 antibodies
Aviva Systems Biology
5 antibodies
Bioworld Technology, Inc
1 antibody
ProSci
2 antibodies
Abbexa
1 antibody
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Creative Biolabs
10 antibodies
RabMAbs
2 antibodies
Arigo
1 antibody
MyBioSource
3 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
64 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Sigma-Aldrich
1 antibody