Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [5]
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Validation data
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- Product number
- NBP1-89091 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-89091, RRID:AB_11041095
- Product name
- Rabbit Polyclonal WDHD1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human WDHD1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.
And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance.
Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Simon AK, Kummer S, Wild S, Lezaja A, Teloni F, Jozwiakowski SK, Altmeyer M, Gari K
Life science alliance 2020 Mar;3(3)
Life science alliance 2020 Mar;3(3)
And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance.
Chen Y, Liu H, Zhang H, Sun C, Hu Z, Tian Q, Peng C, Jiang P, Hua H, Li X, Pei H
Nucleic acids research 2017 Mar 17;45(5):2516-2530
Nucleic acids research 2017 Mar 17;45(5):2516-2530
Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Sato N, Koinuma J, Fujita M, Hosokawa M, Ito T, Tsuchiya E, Kondo S, Nakamura Y, Daigo Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Jan 1;16(1):226-39
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Jan 1;16(1):226-39
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: WDHD1 Antibody [NBP1-89091] - Lane 1: Marker [kDa] 219, 112, 85, 49, 32, 25, 18. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human cell line A-431
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: WDHD1 Antibody [NBP1-89091] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: WDHD1 Antibody [NBP1-89091] - Analysis in human cell line RH-30.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: WDHD1 Antibody [NBP1-89091] - Staining of human testis shows nuclear positivity in cells in seminiferous ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: WDHD1 Antibody [NBP1-89091] - Staining of human rectum shows strong nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: WDHD1 Antibody [NBP1-89091] - Staining of human lymph node shows strong nuclear positivity in germinal center cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: WDHD1 Antibody [NBP1-89091] - Staining of human liver shows no positivity in hepatocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: WDHD1 Antibody [NBP1-89091] - Staining in human testis and liver tissues.. Corresponding WDHD1 RNA-seq data are presented for the same tissues.