WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Description

WD repeat and HMG-box DNA binding protein 1

Tissue specificity

Tissue enhanced (lymphoid tissue)

Subcell location

Nucleoplasm

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (54938949 - 55027105)

Ensembl ID

ENSG00000198554  (ver. 103.38)

Orthologs

Mouse Wdhd1: ENSMUSG00000037572

UniProt

O75717

neXtProt

NX_O75717

Human splice variants
Mouse splice variants

Protein structure