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LearnABIN1881244
antibody from antibodies-online
Targeting: CXCR4
CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881244 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term), (AA 50-79) antibody
- Antibody type
- Polyclonal
- Antigen
- This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,AA 50-79
- Antibody clone number
- RB41207
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells.
CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.
Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus.
Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer.
Zhu S, Hong J, Tripathi MK, Sehdev V, Belkhiri A, El-Rifai W
Molecular cancer research : MCR 2013 Jan;11(1):86-94
Molecular cancer research : MCR 2013 Jan;11(1):86-94
CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.
Cheng M, Zhou J, Wu M, Boriboun C, Thorne T, Liu T, Xiang Z, Zeng Q, Tanaka T, Tang YL, Kishore R, Tomasson MH, Miller RJ, Losordo DW, Qin G
Circulation research 2010 Oct 29;107(9):1083-93
Circulation research 2010 Oct 29;107(9):1083-93
Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus.
Wang A, Guilpain P, Chong BF, Chouzenoux S, Guillevin L, Du Y, Zhou XJ, Lin F, Fairhurst AM, Boudreaux C, Roux C, Wakeland EK, Davis LS, Batteux F, Mohan C
Arthritis and rheumatism 2010 Nov;62(11):3436-46
Arthritis and rheumatism 2010 Nov;62(11):3436-46
Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer.
Hammad MM, Kuang YQ, Yan R, Allen H, Dupré DJ
The Journal of biological chemistry 2010 Nov 5;285(45):34653-64
The Journal of biological chemistry 2010 Nov 5;285(45):34653-64
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CXCR4 Antibody (N-term) (ABIN1881244) western blot analysis in NCI-H460 cell line lysates (35 μg/lane). This demonstrates the CXCR4 antibody detected the CXCR4 protein (arrow).
