Tissue expression
Cell line expression
Protein structure
CXCR4
C-X-C motif chemokine receptor 4CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | ![]() |
5 references | Polyclonal |
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Novus Biologicals | ![]() |
4 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
13 references | Polyclonal |
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R&D Systems | ![]() |
25 references | Monoclonal |
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Proteintech Group | ![]() |
46 references | Polyclonal |
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