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LearnNB100-74396
antibody from Novus Biologicals
Targeting: CXCR4
CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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- Product number
- NB100-74396 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-74396, RRID:AB_1048484
- Product name
- Rabbit Polyclonal CXCR4 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Targeted Delivery of Secretory Promelittin via Novel Poly(lactone-co-β-amino ester) Nanoparticles for Treatment of Breast Cancer Brain Metastases.
Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.
Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells.
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Baicalin attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A(2A) receptor-induced SDF-1/CXCR4/PI3K/AKT signaling.
From glioblastoma to endothelial cells through extracellular vesicles: messages for angiogenesis.
Electroacupuncture modulates stromal cell-derived factor-1α expression and mobilization of bone marrow endothelial progenitor cells in focal cerebral ischemia/reperfusion model rats.
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Tpl2 induces castration resistant prostate cancer progression and metastasis.
Stromal cell-derived factor-1 promoted angiogenesis and inflammatory cell infiltration in aneurysm walls.
Circulating tumor cells from prostate cancer patients interact with E-selectin under physiologic blood flow.
The use of hypoxic cultured mesenchymal stem cell for oncolytic virus therapy.
Adrenaline administration promotes the efficiency of granulocyte colony stimulating factor-mediated hematopoietic stem and progenitor cell mobilization in mice.
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.
Low-intensity pulsed ultrasound accelerates fracture healing by stimulation of recruitment of both local and circulating osteogenic progenitors.
Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after acute myocardial infarction.
Vascular precursors in developing human retina.
CXCR4 regulates interneuron migration in the developing neocortex.
A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia.
Zhou Y, Zhang S, Chen Z, Bao Y, Chen AT, Sheu WC, Liu F, Jiang Z, Zhou J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Mar;7(5):1901866
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Mar;7(5):1901866
Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.
Heo GS, Zhao Y, Sultan D, Zhang X, Detering L, Luehmann HP, Zhang X, Li R, Choksi A, Sharp S, Levingston S, Primeau T, Reichert DE, Sun G, Razani B, Li S, Weilbaecher KN, Dehdashti F, Wooley KL, Liu Y
ACS applied materials & interfaces 2019 Jun 5;11(22):19669-19678
ACS applied materials & interfaces 2019 Jun 5;11(22):19669-19678
Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells.
Ma J, Zhang S, Liu J, Liu F, Du F, Li M, Chen AT, Bao Y, Suh HW, Avery J, Deng G, Zhou Y, Wu P, Sheth K, Wang H, Zhou J
Small (Weinheim an der Bergstrasse, Germany) 2019 Aug;15(35):e1902011
Small (Weinheim an der Bergstrasse, Germany) 2019 Aug;15(35):e1902011
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi M, Siteur B, Hulsman D, Company C, Schmitt MJ, Lieftink C, Morris B, Cesaroni M, Proost N, Beijersbergen RL, van Lohuizen M, Gargiulo G
The Journal of experimental medicine 2018 Dec 3;215(12):3115-3135
The Journal of experimental medicine 2018 Dec 3;215(12):3115-3135
Baicalin attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A(2A) receptor-induced SDF-1/CXCR4/PI3K/AKT signaling.
Huang X, Wu P, Huang F, Xu M, Chen M, Huang K, Li GP, Xu M, Yao D, Wang L
Journal of biomedical science 2017 Aug 3;24(1):52
Journal of biomedical science 2017 Aug 3;24(1):52
From glioblastoma to endothelial cells through extracellular vesicles: messages for angiogenesis.
Giusti I, Delle Monache S, Di Francesco M, Sanità P, D'Ascenzo S, Gravina GL, Festuccia C, Dolo V
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12743-12753
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12743-12753
Electroacupuncture modulates stromal cell-derived factor-1α expression and mobilization of bone marrow endothelial progenitor cells in focal cerebral ischemia/reperfusion model rats.
Xie C, Gao X, Luo Y, Pang Y, Li M
Brain research 2016 Oct 1;1648(Pt A):119-126
Brain research 2016 Oct 1;1648(Pt A):119-126
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Mayorga M, Kiedrowski M, Shamhart P, Forudi F, Weber K, Chilian WM, Penn MS, Dong F
American journal of physiology. Heart and circulatory physiology 2016 Jan 1;310(1):H20-8
American journal of physiology. Heart and circulatory physiology 2016 Jan 1;310(1):H20-8
Tpl2 induces castration resistant prostate cancer progression and metastasis.
Lee HW, Cho HJ, Lee SJ, Song HJ, Cho HJ, Park MC, Seol HJ, Lee JI, Kim S, Lee HM, Choi HY, Nam DH, Joo KM
International journal of cancer 2015 May 1;136(9):2065-77
International journal of cancer 2015 May 1;136(9):2065-77
Stromal cell-derived factor-1 promoted angiogenesis and inflammatory cell infiltration in aneurysm walls.
Hoh BL, Hosaka K, Downes DP, Nowicki KW, Wilmer EN, Velat GJ, Scott EW
Journal of neurosurgery 2014 Jan;120(1):73-86
Journal of neurosurgery 2014 Jan;120(1):73-86
Circulating tumor cells from prostate cancer patients interact with E-selectin under physiologic blood flow.
Gakhar G, Navarro VN, Jurish M, Lee GY, Tagawa ST, Akhtar NH, Seandel M, Geng Y, Liu H, Bander NH, Giannakakou P, Christos PJ, King MR, Nanus DM
PloS one 2013;8(12):e85143
PloS one 2013;8(12):e85143
The use of hypoxic cultured mesenchymal stem cell for oncolytic virus therapy.
Huang YF, Chen MJ, Wu MH, Hung SC
Cancer gene therapy 2013 May;20(5):308-16
Cancer gene therapy 2013 May;20(5):308-16
Adrenaline administration promotes the efficiency of granulocyte colony stimulating factor-mediated hematopoietic stem and progenitor cell mobilization in mice.
Chen C, Cao J, Song X, Zeng L, Li Z, Li Y, Xu K
International journal of hematology 2013 Jan;97(1):50-7
International journal of hematology 2013 Jan;97(1):50-7
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, Parada LF
Cell 2013 Feb 28;152(5):1077-90
Cell 2013 Feb 28;152(5):1077-90
Low-intensity pulsed ultrasound accelerates fracture healing by stimulation of recruitment of both local and circulating osteogenic progenitors.
Kumagai K, Takeuchi R, Ishikawa H, Yamaguchi Y, Fujisawa T, Kuniya T, Takagawa S, Muschler GF, Saito T
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2012 Sep;30(9):1516-21
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2012 Sep;30(9):1516-21
Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after acute myocardial infarction.
Agarwal U, Ghalayini W, Dong F, Weber K, Zou YR, Rabbany SY, Rafii S, Penn MS
Circulation research 2010 Sep 3;107(5):667-76
Circulation research 2010 Sep 3;107(5):667-76
Vascular precursors in developing human retina.
Hasegawa T, McLeod DS, Prow T, Merges C, Grebe R, Lutty GA
Investigative ophthalmology & visual science 2008 May;49(5):2178-92
Investigative ophthalmology & visual science 2008 May;49(5):2178-92
CXCR4 regulates interneuron migration in the developing neocortex.
Stumm RK, Zhou C, Ara T, Lazarini F, Dubois-Dalcq M, Nagasawa T, Höllt V, Schulz S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Jun 15;23(12):5123-30
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Jun 15;23(12):5123-30
A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia.
Stumm RK, Rummel J, Junker V, Culmsee C, Pfeiffer M, Krieglstein J, Höllt V, Schulz S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Jul 15;22(14):5865-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Jul 15;22(14):5865-78
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CXCR4 Antibody [NB100-74396] - Analysis of CXCR4 in HeLa whole cell extract.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CXCR4 Antibody [NB100-74396] - Analysis of CXCR4 protein in human small intestine tissue lysate using 1:500 dilution of rabbit polyclonal CXCR4 antibody (Lot A2). The signal was developed using ECL method and the antibody generated a specific band of CXCR4 at ~40 kDa position.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CXCR4 Antibody [NB100-74396] - Analysis of CXCR4 protein in human small intestine tissue lysate using 1:500 dilution of rabbit polyclonal CXCR4 antibody (Lot A2). The signal was developed using ECL method and the antibody generated a specific band of CXCR4 at ~40 kDa position.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: CXCR4 Antibody [NB100-74396] - Immunostaining of CXCR4 in human cervical carcinoma tissue sections.
