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LearnNBP1-21437
antibody from Novus Biologicals
Targeting: CXCR4
CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R
Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP1-21437 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-21437, RRID:AB_1660003
- Product name
- Goat Polyclonal CXCR4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. NBP1-21437 recognizes an epitope within the N-terminal (NT) region of mouse CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B-lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. NBP1-21437 is reported as suitable for use in immunocytochemistry on mouse spleen leucocytes.
- Reactivity
- Mouse, Xenopus
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
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