RNASEH2C

This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008]

Description

ribonuclease H2 subunit C

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

11:q13.1 (65714005 - 65720818)

Ensembl ID

ENSG00000172922  (ver. 99.38)

Orthologs

Mouse Rnaseh2c: ENSMUSG00000024925

UniProt

Q8TDP1

neXtProt

NX_Q8TDP1

Human splice variants
Mouse splice variants