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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16518-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16518-1-AP, RRID:AB_2181648
- Product name
- RNASEH2C antibody
- Antibody type
- Polyclonal
- Description
- RNASEH2C antibody (Cat. #16518-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.
Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability.
Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair.
Li Y, Shen S, Guo H, Li H, Zhang L, Zhang B, Yu XF, Wei W
Cell reports 2024 Feb 27;43(2):113749
Cell reports 2024 Feb 27;43(2):113749
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.
Zimmermann M, Murina O, Reijns MAM, Agathanggelou A, Challis R, Tarnauskaitė Ž, Muir M, Fluteau A, Aregger M, McEwan A, Yuan W, Clarke M, Lambros MB, Paneesha S, Moss P, Chandrashekhar M, Angers S, Moffat J, Brunton VG, Hart T, de Bono J, Stankovic T, Jackson AP, Durocher D
Nature 2018 Jul;559(7713):285-289
Nature 2018 Jul;559(7713):285-289
Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability.
Pizzi S, Sertic S, Orcesi S, Cereda C, Bianchi M, Jackson AP, Lazzaro F, Plevani P, Muzi-Falconi M
Human molecular genetics 2015 Feb 1;24(3):649-58
Human molecular genetics 2015 Feb 1;24(3):649-58
Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair.
Lindsey-Boltz LA, Kemp MG, Hu J, Sancar A
The Journal of biological chemistry 2015 Dec 11;290(50):29801-7
The Journal of biological chemistry 2015 Dec 11;290(50):29801-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 16518-1-AP(RNASEH2C antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16518-1-AP(RNASEH2C antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RNASEH2C antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RNASEH2C. This antibody recognizes human antigen. The RNASEH2C antibody has been validated for the following applications: ELISA, WB, IHC analysis.
