BAG4

gene product
SODD
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
383 antibodies from 39 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
11 antibodies
Affinity Biosciences
1 antibody
antibodies-online
138 antibodies
LifeSpan BioSciences, Inc.
68 antibodies
Biorbyt
27 antibodies
Antibodies.com
1 antibody
NovoPro Bioscience Inc.
1 antibody
NSJ Bioreagents
1 antibody
Abnova Corporation
9 antibodies
OriGene
8 antibodies
Acris Antibodies GmbH
8 antibodies
R&D Systems
2 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
6 antibodies
GeneTex
3 antibodies
Enzo Life Sciences
1 antibody
Abgent
5 antibodies
St John's Laboratory
3 antibodies
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
RabMAbs
4 antibodies
Aviva Systems Biology
7 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Everest Biotech
1 antibody
Arigo
2 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Creative Biolabs
4 antibodies
Creative Diagnostics
6 antibodies
MyBioSource
10 antibodies
RayBiotech, Inc.
4 antibodies
Abiocode, Inc.
1 antibody
Boster Biological Technology
1 antibody
United States Biological
33 antibodies
Sigma-Aldrich
3 antibodies
Abbexa
3 antibodies
GenWay
2 antibodies
EMD Millipore
1 antibody
Exalpha Biologicals, Inc.
1 antibody