PA5-46830

antibody from Invitrogen Antibodies

Targeting: GABRP

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-46830

Provider

Invitrogen Antibodies

Product name

GABRP Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Peptide sequence: VEVGRSDKLS LPGFENLTAG YNKFLRPNFG GEPVQIALTL DIASISSISE Sequence homology: Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.5 mg/mL

Storage

-20° C, Avoid Freeze/Thaw Cycles

References

Submitted references

GABRP is a potential prognostic biomarker and correlated with immune infiltration and tumor microenvironment in pancreatic cancer.

Yang Y, Ren L, Li S, Zheng X, Liu J, Li W, Fu W, Wang J, Du G
Translational cancer research 2022 Apr;11(4):649-668

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 1 GABRP mRNA expression was upregulated in pancreatic cancer. (A) The flowchart of study procedures; (B) the expression level of GABRP was measured in different types of tumor tissues and compared with normal tissues in the GEPIA2 database; (C) the expression level of GABRP was measured in different types of tumor tissues and normal tissues using the Oncomine database (P value is 0.001, fold change is 2, and gene rankings apply to all); (D) GABRP expression in tumors and matching normal tissues using two independent cohorts (GSE15471, n=78; GSE16515, n=52) derived from Gene Expression Omnibus datasets; (E) immunohistochemical analysis of GABRP expression in a human PDAC tissue microarray. Representative GABRP images are shown in the left panel. The percentages of tissues displaying low and high staining in normal pancreas and PDAC tissues are shown in the middle panel. ****, P