12-1719-42

antibody from Invitrogen Antibodies
Targeting: L1CAM CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1
Provider product page for 12-1719-42

Antibody data

Product number
12-1719-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD171 Monoclonal Antibody (eBio5G3 (5G3)), PE, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The monoclonal antibody eBio5G3 recognizes CD171 also known as neural cell adhesion molecule L1. CD171 is a member of the Ig superfamily containing 6 extracellular Ig domains and five fibronectin type III-like repeats. CD171 has been shown to function as a cell adhesion molecule mediating homotypic and heterotypic cell-cell interactions in neuronal myelination, neurite outgrowth and regeneration. Expression of CD171 has been found on monocytes and mature monocytic-derived and follicular DCs, a minor subset of lymphocytes in addition to that found on neuronal tissue and some tumor cells lines. Expression of CD171 on tumors is thought to contribute to tumor progression. Epitope of eBio5G3 is in amino-terminal Ig-like domain. Applications Reported: This eBio5G3 (5G3) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio5G3 (5G3) antibody has been pre-titrated and tested by flow cytometric analysis of tumor cell line Panc-1. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Antibody clone number
eBio5G3 (5G3)
Vial size
100 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
L1CAM protein structure - 12-1719-42 shown in red.