L1CAM

gene product
CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
632 antibodies from 38 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Invitrogen Antibodies
11 antibodies
OriGene
51 antibodies
Novus Biologicals
91 antibodies
GeneTex
24 antibodies
antibodies-online
172 antibodies
Abgent
1 antibody
NSJ Bioreagents
4 antibodies
LifeSpan BioSciences, Inc.
93 antibodies
R&D Systems
13 antibodies
Bioworld Technology, Inc
1 antibody
Acris Antibodies GmbH
10 antibodies
Cell Signaling Technology, Inc
2 antibodies
Aviva Systems Biology
3 antibodies
Atlas Antibodies
1 antibody
BioLegend
7 antibodies
Abnova Corporation
3 antibodies
Biorbyt
24 antibodies
NovoPro Bioscience Inc.
11 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Creative Diagnostics
7 antibodies
MyBioSource
11 antibodies
GenWay
3 antibodies
EMD Millipore
2 antibodies
Arigo
1 antibody
United States Biological
26 antibodies
St John's Laboratory
5 antibodies
Sino Biological Inc.
8 antibodies
Creative Biolabs
14 antibodies
eBioscience, An Affymetrix Company
5 antibodies
BioLegend (formerly Covance Antibody Products)
2 antibodies
ProSci
1 antibody
Signalway Antibody LLC
1 antibody
Sigma-Aldrich
1 antibody
Abbexa
3 antibodies