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LearnNBP2-34753JF646
antibody from Novus Biologicals
Targeting: L1CAM
CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-34753JF646 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal L1CAM Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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