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- Antibody Data
- Antigen structure
- References [120]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 13098-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13098-1-AP, RRID:AB_2278042
- Product name
- FAS/CD95 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FAS/CD95 antibody (Cat. #13098-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ALDH3A1 upregulation inhibits neutrophils N2 polarization and halts oral cancer growth.
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Effects of Hericium erinaceus polysaccharide in porcine IPEC-J2 intestinal epithelial cells against apoptosis induced by oxidative stress.
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C.
Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts.
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Preliminary study of donor volume changes after dual-graft liver transplantation in rats.
Comparative effects of hepatocyte growth factor and tacrolimus on acute liver allograft early tolerance.
ZNF655 promotes the progression of hepatocellular carcinoma through PSMB8.
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Copper exposure induces ovarian granulosa cell apoptosis by activating the caspase-dependent apoptosis signaling pathway and corresponding changes in microRNA patterns.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Dual role of NR4A1 in porcine ovarian granulosa cell differentiation and granulosa-lutein cell regression in vitro.
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Modulation of the Microbiome-Fat-Liver Axis by Lactic Acid Bacteria: A Potential Alleviated Role in High-Fat-Diet-Induced Obese Mice.
Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis.
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Analyzing roles of small nucleolar RNA host gene 25 from clinical, molecular target and tumor formation in prostate cancer.
Weizmannia coagulans JA845 improves atherosclerosis induced by vitamin D3 and high-fat diet in rats through modulating lipid metabolism, oxidative stress, and endothelial vascular injury.
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy.
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.
Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells.
Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission.
Curcumin represses lipid accumulation through inhibiting ERK1/2-PPAR-γ signaling pathway and triggering apoptosis in porcine subcutaneous preadipocytes.
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness.
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells.
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription.
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
3'-Sulfo-TF Antigen Determined by GAL3ST2/ST3GAL1 Is Essential for Antitumor Activity of Fungal Galectin AAL/AAGL.
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells.
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx.
Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway.
AGEs exacerbates coronary microvascular dysfunction in NoCAD by activating endoplasmic reticulum stress-mediated PERK signaling pathway.
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Colon Adenocarcinoma Metastasis.
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity.
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
miR-196b-5p-mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling.
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells.
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain.
Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism.
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
MicroRNA-128 is involved in dexamethasone-induced lipid accumulation via repressing SIRT1 expression in cultured pig preadipocytes.
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE(-/-) Mice Exposed to Chronic Mild Stress.
MicroRNA‑143 increases cell apoptosis in myelodysplastic syndrome through the Fas/FasL pathway both in vitro and in vivo.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo.
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
11β-hydroxysteroid dehydrogenases-2 decreases the apoptosis of MC3T3/MLO-Y4 cells induced by glucocorticoids.
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
Loss of Fas expression and high expression of HLA-E promoting the immune escape of early colorectal cancer cells.
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1.
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
He Y, Qu Y, Jin S, Zhang Y, Qin L
Oral diseases 2024 Oct;30(7):4231-4242
Oral diseases 2024 Oct;30(7):4231-4242
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Ma H, Suleman M, Zhang F, Cao T, Wen S, Sun D, Chen L, Jiang B, Wang Y, Lin F, Wang J, Li B, Li Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Effects of Hericium erinaceus polysaccharide in porcine IPEC-J2 intestinal epithelial cells against apoptosis induced by oxidative stress.
Li J, Mo JR, Hu SY, Dong X, Li JW, Yang LY, Wu YJ
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Jun;280:109902
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Jun;280:109902
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Zhang T, Wang X, Wang D, Lei M, Hu Y, Chen Z, Li Y, Luo Y, Zhang L, Zhu Y
Biomaterials advances 2024 Jun;160:213859
Biomaterials advances 2024 Jun;160:213859
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Lin H, Li J, Sun M, Wang X, Zhao J, Zhang W, Lv G, Wang Y, Lin Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C.
Suo J, Wang Y, Wang L, Qiu B, Wang Z, Yan A, Qiang B, Han W, Peng X
FEBS open bio 2024 Jan;14(1):138-147
FEBS open bio 2024 Jan;14(1):138-147
Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts.
Wu Y, Wu Y, Yu J, Zhang Y, Dai X, Chen J, Sun Y, Yang Y, Zhao K, Xiao Q
Molecular and cellular biochemistry 2024 Apr 6;
Molecular and cellular biochemistry 2024 Apr 6;
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
Zheng Z, Gao W, Zhu Z, Li S, Chen X, Cravotto G, Sui Y, Zhou L
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J
Frontiers in immunology 2023;14:1304529
Frontiers in immunology 2023;14:1304529
Preliminary study of donor volume changes after dual-graft liver transplantation in rats.
Wang D, Ma Y, Gu B, Li X, Yu Y, Zhang Y, Chen H
Frontiers in immunology 2023;14:1183426
Frontiers in immunology 2023;14:1183426
Comparative effects of hepatocyte growth factor and tacrolimus on acute liver allograft early tolerance.
Chen Q, Yang Z, Lin H, Lai J, Hu D, Yan M, Wu Z, Liu W, Li Z, He Y, Sun Z, Shuai L, Peng Z, Wang Y, Li S, Cui Y, Zhang H, Zhang L, Bai L
Frontiers in immunology 2023;14:1162439
Frontiers in immunology 2023;14:1162439
ZNF655 promotes the progression of hepatocellular carcinoma through PSMB8.
Fan S, Liu Y, Lin Z, Zhang Y, Zhang N, Zhao Y, Zhou J, Mao A, Wang L, Feng Y, He X, Wang L, Pan Q
Cell biology international 2023 Sep;47(9):1535-1546
Cell biology international 2023 Sep;47(9):1535-1546
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Nůsková H, Cortizo FG, Schwenker LS, Sachsenheimer T, Diakonov EE, Tiebe M, Schneider M, Lohbeck J, Reid C, Kopp-Schneider A, Helm D, Brügger B, Miller AK, Teleman AA
The Journal of biological chemistry 2023 Sep;299(9):105088
The Journal of biological chemistry 2023 Sep;299(9):105088
Copper exposure induces ovarian granulosa cell apoptosis by activating the caspase-dependent apoptosis signaling pathway and corresponding changes in microRNA patterns.
Chen Y, Guan F, Wang P, Liu W, Zhang W, Sun H, Zhu L, Huang Y, Sun Y, Wang W
Ecotoxicology and environmental safety 2023 Oct 1;264:115414
Ecotoxicology and environmental safety 2023 Oct 1;264:115414
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
Dual role of NR4A1 in porcine ovarian granulosa cell differentiation and granulosa-lutein cell regression in vitro.
Yu H, Zhao J, Pei X, Xia Y, Li H, Wang W, Mao D
Theriogenology 2023 Mar 1;198:292-304
Theriogenology 2023 Mar 1;198:292-304
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Wu Y, Duan Z, Qu L, Zhang Y, Zhu C, Fan D
Food & function 2023 Jun 6;14(11):5167-5181
Food & function 2023 Jun 6;14(11):5167-5181
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Song D, Zhang A, Hu X, Zeng M, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Modulation of the Microbiome-Fat-Liver Axis by Lactic Acid Bacteria: A Potential Alleviated Role in High-Fat-Diet-Induced Obese Mice.
Wei B, Peng Z, Xiao M, Huang T, Yang S, Liu K, Wu M, Zheng W, Xie M, Xiong T
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10361-10374
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10361-10374
Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis.
Zhang L, Li L, Chen X, Yuan S, Xu T, Zhao W, Li M, Wang F, Hoffman RM, Jia L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154493
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154493
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Ding JF, Zhou Y, Xu SS, Shi KH, Sun H, Tu B, Song K, Xuan HY, Sha JM, Zhao JY, Tao H
European journal of pharmacology 2023 Jan 5;938:175398
European journal of pharmacology 2023 Jan 5;938:175398
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Zhang X, Xiao Y, Huang Q
International journal of biological macromolecules 2023 Aug 30;247:125747
International journal of biological macromolecules 2023 Aug 30;247:125747
Analyzing roles of small nucleolar RNA host gene 25 from clinical, molecular target and tumor formation in prostate cancer.
Liu Z, Ke S, Wang Q, Gu X, Zhai G, Shao H, He M, Guo J
Experimental cell research 2023 Aug 15;429(2):113686
Experimental cell research 2023 Aug 15;429(2):113686
Weizmannia coagulans JA845 improves atherosclerosis induced by vitamin D3 and high-fat diet in rats through modulating lipid metabolism, oxidative stress, and endothelial vascular injury.
Ma L, Zhao Z, Zhao Y, Gao Y, Zhao L, Li S
Journal of applied microbiology 2023 Aug 1;134(8)
Journal of applied microbiology 2023 Aug 1;134(8)
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Liu J, Li W, Bian Y, Jiang X, Zhu F, Yin F, Yin L, Song X, Guo H, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154679
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154679
A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy.
Cui T, Zhang Y, Qin G, Wei Y, Yang J, Huang Y, Ren J, Qu X
Nature communications 2023 Apr 8;14(1):1974
Nature communications 2023 Apr 8;14(1):1974
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838
Frontiers in nutrition 2022;9:911838
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Gu W, Yang L, Wang X, Geng J, Li X, Zheng K, Guan Y, Hou X, Wang C, Song G
Kidney & blood pressure research 2022;47(8):514-522
Kidney & blood pressure research 2022;47(8):514-522
Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.
Jin X, Dai G, Xuan L, Zhang M, Jiang H, Sui Y
Journal of immunology research 2022;2022:6792866
Journal of immunology research 2022;2022:6792866
Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.
Peng Z, Li M, Wang Y, Yang H, Wei W, Liang M, Shi J, Liu R, Li R, Zhang Y, Liu J, Shi X, Wan R, Fu Y, Xie R, Wang Y
Frontiers in cell and developmental biology 2022;10:698282
Frontiers in cell and developmental biology 2022;10:698282
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells.
Zhang W, Liu J, Li Y, Guo F
Cancer chemotherapy and pharmacology 2022 Sep;90(3):251-265
Cancer chemotherapy and pharmacology 2022 Sep;90(3):251-265
Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission.
Chen XJ, Cui QX, Wang GL, Li XL, Zhou XL, Zhao HJ, Zhang MQ, Li MJ, He XJ, Zheng QS, Wang YL, Li D, Hong P
Journal of natural products 2022 Oct 28;85(10):2351-2362
Journal of natural products 2022 Oct 28;85(10):2351-2362
Curcumin represses lipid accumulation through inhibiting ERK1/2-PPAR-γ signaling pathway and triggering apoptosis in porcine subcutaneous preadipocytes.
Pan S, Chen Y, Zhang L, Liu Z, Xu X, Xing H
Animal bioscience 2022 May;35(5):763-777
Animal bioscience 2022 May;35(5):763-777
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
Yang M, Feng J, Lan X, Tang Y, Zhang Y, Zhang H, Wang S
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness.
Chen Y, Zhao M, Zhang L, Shen D, Xu X, Yi Q, Tang L
Translational oncology 2022 Mar;17:101335
Translational oncology 2022 Mar;17:101335
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Zhao CZ, Jiang W, Zhu YY, Wang CZ, Zhong WH, Wu G, Chen J, Zhu MN, Wu QL, Du XL, Luo YY, Li M, Wang HL, Zhao H, Ma QG, Zhong GY, Wei RR
Journal of ethnopharmacology 2022 Mar 25;286:114922
Journal of ethnopharmacology 2022 Mar 25;286:114922
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
Liu Z, Wang Q, Zhai G, Ke S, Yu X, Guo J
Cancer cell international 2022 Mar 19;22(1):127
Cancer cell international 2022 Mar 19;22(1):127
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells.
Wu YN, Zhang R, Song XC, Han XX, Zhang J, Li X
Cellular immunology 2022 Jan;371:104467
Cellular immunology 2022 Jan;371:104467
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
Li R, Xiao J, Cao Y, Huang Q, Ho CT, Lu M
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
Lin K, Shen SH, Lu F, Zheng P, Wu S, Liao J, Jiang X, Zeng G, Wei D
Journal of translational medicine 2022 Feb 19;20(1):96
Journal of translational medicine 2022 Feb 19;20(1):96
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Chen Q, Han H, Lin F, Yang L, Feng L, Lai X, Wen Z, Yang M, Wang C, Ma Y, Yin T, Lu G, Lin H, Qi J, Yang Y
Life sciences 2022 Dec 1;310:121077
Life sciences 2022 Dec 1;310:121077
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription.
Hou P, Lin T, Meng S, Shi M, Chen F, Jiang T, Li Z, Li M, Chu S, Zheng J, Bai J
International journal of biological sciences 2021;17(8):1979-1994
International journal of biological sciences 2021;17(8):1979-1994
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Jiang MJ, Li L, Huang WF, Su J, Li YH, Qu XS, Fan LL
Journal of natural medicines 2021 Sep;75(4):884-892
Journal of natural medicines 2021 Sep;75(4):884-892
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Dong JY, Xia KJ, Liang W, Liu LL, Yang F, Fang XS, Xiong YJ, Wang L, Zhou ZJ, Li CY, Zhang WD, Wang JY, Chen DP
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis.
Zhang L, Wang X, Li Y, Han J, Gao X, Li S, Wang F
Clinical and translational medicine 2021 Sep;11(9):e464
Clinical and translational medicine 2021 Sep;11(9):e464
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, Kenny HA, Vaisar T, Lengyel E, Greene G, Becker L
Cell 2021 Jun 10;184(12):3163-3177.e21
Cell 2021 Jun 10;184(12):3163-3177.e21
3'-Sulfo-TF Antigen Determined by GAL3ST2/ST3GAL1 Is Essential for Antitumor Activity of Fungal Galectin AAL/AAGL.
Li Y, Li Y, Xia J, Yang Q, Chen Y, Sun H
ACS omega 2021 Jul 13;6(27):17379-17390
ACS omega 2021 Jul 13;6(27):17379-17390
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
Zheng X, Liu D
Life sciences 2021 Jan 15;265:118825
Life sciences 2021 Jan 15;265:118825
Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells.
Qi W, Xu Q, Xu Y, Wang Z, Yang L, Guo S, Shi Y, Zhao T, Zhou L, Ye L
Ecotoxicology and environmental safety 2021 Jan 15;208:111472
Ecotoxicology and environmental safety 2021 Jan 15;208:111472
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Zhang J, Yang S, Guan H, Zhou J, Gao Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Luo H, Chen CY, Li X, Zhang X, Su CW, Liu Y, Cao T, Hao L, Wang M, Kang JX
Stem cells (Dayton, Ohio) 2021 Dec;39(12):1660-1670
Stem cells (Dayton, Ohio) 2021 Dec;39(12):1660-1670
Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
Pan S, Zhang L, Liu Z, Xing H
Journal of animal science 2021 Dec 1;99(12)
Journal of animal science 2021 Dec 1;99(12)
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx.
Yang F, Duan M, Zheng F, Yu L, Wang Y, Wang G, Lin J, Han S, Gan D, Meng Z, Zhu S
Cancer letters 2021 Dec 1;522:93-104
Cancer letters 2021 Dec 1;522:93-104
Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway.
Li H, Niu N, Yang J, Dong F, Zhang T, Li S, Zhao W
Cell biology international 2021 Aug;45(8):1784-1796
Cell biology international 2021 Aug;45(8):1784-1796
AGEs exacerbates coronary microvascular dysfunction in NoCAD by activating endoplasmic reticulum stress-mediated PERK signaling pathway.
Liu Z, Zhu H, Ma Y, Tang Z, Zhao N, Wang Y, Pan S
Metabolism: clinical and experimental 2021 Apr;117:154710
Metabolism: clinical and experimental 2021 Apr;117:154710
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Colon Adenocarcinoma Metastasis.
Chang Z, Huang R, Fu W, Li J, Ji G, Huang J, Shi W, Yin H, Wang W, Meng T, Huang Z, Wei Q, Qin H
Frontiers in cell and developmental biology 2020;8:688
Frontiers in cell and developmental biology 2020;8:688
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Lin HY, Han HW, Wang YS, He DL, Sun WX, Feng L, Wen ZL, Yang MK, Lu GH, Wang XM, Qi JL, Yang YH
Chinese medicine 2020;15:23
Chinese medicine 2020;15:23
Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity.
Li H, An X, Zhang D, Li Q, Zhang N, Yu H, Li Z
OncoTargets and therapy 2020;13:1211-1223
OncoTargets and therapy 2020;13:1211-1223
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
Wang C, Song D, Fu J, Wen X
Frontiers in endocrinology 2020;11:580
Frontiers in endocrinology 2020;11:580
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Chen K, Ma Z, Yan X, Liu J, Xu W, Li Y, Dai Y, Zhang Y, Xiao H
Frontiers in pharmacology 2020;11:528
Frontiers in pharmacology 2020;11:528
miR-196b-5p-mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling.
Huang X, Xiao S, Zhu X, Yu Y, Cao M, Zhang X, Li S, Zhu W, Wu F, Zheng X, Jin L, Xie C, Huang X, Zou P, Li X, Cui R
Cell death & disease 2020 Sep 22;11(9):785
Cell death & disease 2020 Sep 22;11(9):785
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
Feng Z, Pang L, Chen S, Pang X, Huang Y, Qiao Q, Wang Y, Vonglorkham S, Huang Q, Lin X, Wei J
International immunopharmacology 2020 Nov;88:107003
International immunopharmacology 2020 Nov;88:107003
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X
Life sciences 2020 Mar 15;245:117387
Life sciences 2020 Mar 15;245:117387
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701
Cell proliferation 2020 Jan;53(1):e12701
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Guo M, Chen H, Duan W, Li Z, Li Y, Ma Y, Xu X, Yi L, Bi Y, Liu Y, Zhang J, Li C
Brain research bulletin 2020 Jan;154:91-101
Brain research bulletin 2020 Jan;154:91-101
C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells.
Kim HJ, Seo BG, Kim KD, Yoo J, Lee JH, Min BS, Lee JH, Hwangbo C
International journal of molecular sciences 2020 Feb 14;21(4)
International journal of molecular sciences 2020 Feb 14;21(4)
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Han J, Kan J, Wang X, Yuan Q, Song X, Huang M, Wu H
Translational cancer research 2020 Aug;9(8):4715-4725
Translational cancer research 2020 Aug;9(8):4715-4725
Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain.
Li Q, Yang J, Zhang J, Liu XW, Yang CJ, Fan ZX, Wang HB, Yang Y, Zheng T, Yang J
Journal of cellular physiology 2020 Apr;235(4):3753-3767
Journal of cellular physiology 2020 Apr;235(4):3753-3767
Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism.
Qiao X, Zhou ZC, Niu R, Su YT, Sun Y, Liu HL, Teng JL, Ye JN, Shi H, Yang CD, Cheng XB
Frontiers in pharmacology 2019;10:855
Frontiers in pharmacology 2019;10:855
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Wang L, Li S, Yu X, Han Y, Wu Y, Wang S, Chen X, Zhang J, Wang S
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
Deng C, Li J, Li L, Sun F, Xie J
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
MicroRNA-128 is involved in dexamethasone-induced lipid accumulation via repressing SIRT1 expression in cultured pig preadipocytes.
Pan S, Cui Y, Fu Z, Zhang L, Xing H
The Journal of steroid biochemistry and molecular biology 2019 Feb;186:185-195
The Journal of steroid biochemistry and molecular biology 2019 Feb;186:185-195
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Kong M, Chen X, Xu H, Wenping, Fang M, Xu Y
Biochemical and biophysical research communications 2018 Sep 3;503(1):344-351
Biochemical and biophysical research communications 2018 Sep 3;503(1):344-351
Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
Verlekar D, Wei SJ, Cho H, Yang S, Kang MH
Cell death & disease 2018 Sep 11;9(9):925
Cell death & disease 2018 Sep 11;9(9):925
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Qin DD, Yang YF, Pu ZQ, Liu D, Yu C, Gao P, Chen JC, Zong C, Zhang YC, Li X, Wang XD, Liu YT
Journal of cellular and molecular medicine 2018 Oct;22(10):4709-4720
Journal of cellular and molecular medicine 2018 Oct;22(10):4709-4720
6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE(-/-) Mice Exposed to Chronic Mild Stress.
Wang S, Tian M, Yang R, Jing Y, Chen W, Wang J, Zheng X, Wang F
Cardiovascular toxicology 2018 Oct;18(5):420-430
Cardiovascular toxicology 2018 Oct;18(5):420-430
MicroRNA‑143 increases cell apoptosis in myelodysplastic syndrome through the Fas/FasL pathway both in vitro and in vivo.
Cui J, Wei C, Deng L, Kuang X, Zhang Z, Pierides C, Chi J, Wang L
International journal of oncology 2018 Nov;53(5):2191-2199
International journal of oncology 2018 Nov;53(5):2191-2199
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Li LN, Wang L, Cheng YN, Cao ZQ, Zhang XK, Guo XL
Molecular pharmaceutics 2018 Nov 5;15(11):4898-4911
Molecular pharmaceutics 2018 Nov 5;15(11):4898-4911
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Yang Y, Yang H, Xu M, Zhang H, Sun M, Mu P, Dong T, Du S, Liu K
Human cell 2018 Jul;31(3):232-241
Human cell 2018 Jul;31(3):232-241
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Zhong H, Chen K, Feng M, Shao W, Wu J, Chen K, Liang T, Liu C
The FEBS journal 2018 Feb;285(3):501-517
The FEBS journal 2018 Feb;285(3):501-517
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo.
Chen Z, You L, Wang L, Huang X, Liu H, Wei JY, Zhu L, Qian W
Journal of experimental & clinical cancer research : CR 2018 Aug 13;37(1):190
Journal of experimental & clinical cancer research : CR 2018 Aug 13;37(1):190
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
Pan S, Jia Y, Yang X, Cai D, Liu Z, Song H, Zhao R
European journal of nutrition 2018 Apr;57(3):991-1001
European journal of nutrition 2018 Apr;57(3):991-1001
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Jiang Z, Song F, Li Y, Xue D, Zhao N, Zhang J, Deng G, Li M, Liu X, Wang Y
Oxidative medicine and cellular longevity 2017;2017:6175841
Oxidative medicine and cellular longevity 2017;2017:6175841
11β-hydroxysteroid dehydrogenases-2 decreases the apoptosis of MC3T3/MLO-Y4 cells induced by glucocorticoids.
Zhang H, Zhou F, Pan Z, Bu X, Wang Y, Chen F
Biochemical and biophysical research communications 2017 Sep 2;490(4):1399-1406
Biochemical and biophysical research communications 2017 Sep 2;490(4):1399-1406
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Pan S, Cui Y, Dong X, Zhang T, Xing H
Oncotarget 2017 Oct 20;8(50):87928-87943
Oncotarget 2017 Oct 20;8(50):87928-87943
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
Shen R, Liu D, Hou C, Liu D, Zhao L, Cheng J, Wang D, Bai D
Food & function 2017 Oct 18;8(10):3636-3646
Food & function 2017 Oct 18;8(10):3636-3646
Loss of Fas expression and high expression of HLA-E promoting the immune escape of early colorectal cancer cells.
Huang R, Zhang D, Li F, Xiao Z, Wu M, Shi D, Xiang P, Bao Z
Oncology letters 2017 May;13(5):3379-3386
Oncology letters 2017 May;13(5):3379-3386
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
Chen S, Wen X, Zhang W, Wang C, Liu J, Liu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Mar;31(3):1085-1096
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Mar;31(3):1085-1096
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K
Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.
Lei X, Cui K, Li Z, Su J, Jiang J, Zhang H, Liu Q, Shi D
Theriogenology 2016 Mar 15;85(5):999-1012
Theriogenology 2016 Mar 15;85(5):999-1012
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Ding C, Zhao Y, Shi X, Zhang N, Zu G, Li Z, Zhou J, Gao D, Lv L, Tian X, Yao J
Scientific reports 2016 Jun 27;6:28734
Scientific reports 2016 Jun 27;6:28734
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, Shi D
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ma Z, Hou T, Shi W, Liu W, He H
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Liang ZE, Yi YJ, Guo YT, Wang RC, Hu QL, Xiong XY
Molecular medicine reports 2015 Nov;12(5):7629-36
Molecular medicine reports 2015 Nov;12(5):7629-36
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Song X, Li L, Shi Q, Lehmler HJ, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Nov 16;28(11):2160-9
Chemical research in toxicology 2015 Nov 16;28(11):2160-9
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Huang Y, Du Y, Zhang X, Bai L, Mibrahim M, Zhang J, Wei Y, Li C, Fan S, Wang H, Zhao Z, Tang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:146-50
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:146-50
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Wang D, Chen S, Liu M, Liu C
Chronobiology international 2015 Jun;32(5):615-26
Chronobiology international 2015 Jun;32(5):615-26
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Zhang M, Yang J, Shu J, Fu C, Liu S, Xu G, Zhang D
Nanoscale research letters 2014;9(1):616
Nanoscale research letters 2014;9(1):616
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
Yang X, Xu Y, Guo F, Ning Y, Zhi X, Yin L, Li X
PloS one 2013;8(4):e60853
PloS one 2013;8(4):e60853
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Wang Q, Dong Z, Liu X, Song X, Song Q, Shang Q, Jiang Y, Guo C, Zhang L
Diabetes 2013 Dec;62(12):4132-43
Diabetes 2013 Dec;62(12):4132-43
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1.
Bucciantini M, Nosi D, Forzan M, Russo E, Calamai M, Pieri L, Formigli L, Quercioli F, Soria S, Pavone F, Savistchenko J, Melki R, Stefani M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Feb;26(2):818-31
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Feb;26(2):818-31
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Yin Y, Chen W, Tang C, Ding H, Jang J, Weng M, Cai Y, Zou G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011 Dec;49(12):3046-54
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011 Dec;49(12):3046-54
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Chen W, Hou J, Yin Y, Jang J, Zheng Z, Fan H, Zou G
Biochemical pharmacology 2010 Jul 15;80(2):247-54
Biochemical pharmacology 2010 Jul 15;80(2):247-54
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13098-1-AP(FAS antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-FAS (IP:13098-1-AP, 3ug; Detection:13098-1-AP 1:500) with HeLa cells lysate 3000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FAS/CD95 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FAS/CD95. This antibody recognizes human antigen. The FAS/CD95 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
