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Immunohistochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 305602 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#305602, RRID:AB_314540
- Product name
- Purified anti-human CD95 (Fas)
- Antibody type
- Monoclonal
- Antigen
- CD95 transfected L cells
- Description
- CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16.
Xie S, Li J, Wang JH, Wu Q, Yang P, Hsu HC, Smythies LE, Mountz JD
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2289-96
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2289-96
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- BioLegend (provider)
- Main image
- Experimental details
- Whole blood lymphocytes stained with DX2 PE/Cy5
- Conjugate
- Unconjugated
