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Immunocytochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [16]
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- Flow cytometry [1]
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- Product number
- ABIN1106610 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody
- Antibody type
- Monoclonal
- Description
- Ammonium sulfate precipitation and affinity chromatography on protein A agarose
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- UB2
- Vial size
- 0.1 mg
- Storage
- Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells.
Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis.
Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively.
Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways.
Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation.
Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation.
Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy.
The involvement of Fas-Fas ligand pathway in fibrosing lung diseases.
Functional Fas ligand expression in thyrocytes from patients with Graves' disease.
Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis.
Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL.
Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis.
Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders.
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis.
Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication.
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.
Mezosi E, Wang SH, Utsugi S, Bajnok L, Bretz JD, Gauger PG, Thompson NW, Baker JR Jr
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):804-11
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):804-11
Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis.
Hauptschein RS, Sloan KE, Torella C, Moezzifard R, Giel-Moloney M, Zehetmeier C, Unger C, Ilag LL, Jay DG
Cancer research 2005 Mar 1;65(5):1887-96
Cancer research 2005 Mar 1;65(5):1887-96
Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively.
Vega MI, Jazirehi AR, Huerta-Yepez S, Bonavida B
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 15;175(4):2174-83
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 15;175(4):2174-83
Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways.
Suhara T, Fukuo K, Yasuda O, Tsubakimoto M, Takemura Y, Kawamoto H, Yokoi T, Mogi M, Kaimoto T, Ogihara T
Hypertension (Dallas, Tex. : 1979) 2004 Jun;43(6):1208-13
Hypertension (Dallas, Tex. : 1979) 2004 Jun;43(6):1208-13
Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation.
Suhara T, Kim HS, Kirshenbaum LA, Walsh K
Molecular and cellular biology 2002 Jan;22(2):680-91
Molecular and cellular biology 2002 Jan;22(2):680-91
Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation.
Shinohara H, Yagita H, Ikawa Y, Oyaizu N
Cancer research 2000 Mar 15;60(6):1766-72
Cancer research 2000 Mar 15;60(6):1766-72
Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy.
Sata M, Suhara T, Walsh K
Arteriosclerosis, thrombosis, and vascular biology 2000 Feb;20(2):309-16
Arteriosclerosis, thrombosis, and vascular biology 2000 Feb;20(2):309-16
The involvement of Fas-Fas ligand pathway in fibrosing lung diseases.
Kuwano K, Miyazaki H, Hagimoto N, Kawasaki M, Fujita M, Kunitake R, Kaneko Y, Hara N
American journal of respiratory cell and molecular biology 1999 Jan;20(1):53-60
American journal of respiratory cell and molecular biology 1999 Jan;20(1):53-60
Functional Fas ligand expression in thyrocytes from patients with Graves' disease.
Hiromatsu Y, Hoshino T, Yagita H, Koga M, Sakisaka S, Honda J, Yang D, Kayagaki N, Okumura K, Nonaka K
The Journal of clinical endocrinology and metabolism 1999 Aug;84(8):2896-902
The Journal of clinical endocrinology and metabolism 1999 Aug;84(8):2896-902
Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis.
Dai CH, Price JO, Brunner T, Krantz SB
Blood 1998 Feb 15;91(4):1235-42
Blood 1998 Feb 15;91(4):1235-42
Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL.
Ando K, Hiroishi K, Kaneko T, Moriyama T, Muto Y, Kayagaki N, Yagita H, Okumura K, Imawari M
Journal of immunology (Baltimore, Md. : 1950) 1997 Jun 1;158(11):5283-91
Journal of immunology (Baltimore, Md. : 1950) 1997 Jun 1;158(11):5283-91
Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis.
Boirivant M, Pica R, DeMaria R, Testi R, Pallone F, Strober W
The Journal of clinical investigation 1996 Dec 1;98(11):2616-22
The Journal of clinical investigation 1996 Dec 1;98(11):2616-22
Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders.
Hata H, Matsuzaki H, Takeya M, Yoshida M, Sonoki T, Nagasaki A, Kuribayashi N, Kawano F, Takatsuki K
Blood 1995 Sep 1;86(5):1939-45
Blood 1995 Sep 1;86(5):1939-45
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis.
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S
Nature 1992 Mar 26;356(6367):314-7
Nature 1992 Mar 26;356(6367):314-7
Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication.
Kobayashi N, Hamamoto Y, Yamamoto N, Ishii A, Yonehara M, Yonehara S
Proceedings of the National Academy of Sciences of the United States of America 1990 Dec;87(24):9620-4
Proceedings of the National Academy of Sciences of the United States of America 1990 Dec;87(24):9620-4
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.
Yonehara S, Ishii A, Yonehara M
The Journal of experimental medicine 1989 May 1;169(5):1747-56
The Journal of experimental medicine 1989 May 1;169(5):1747-56
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