DCABH-3230

antibody from Creative Diagnostics

Targeting: BCL10 c-E10, CARMEN, CIPER, CLAP, mE10

No application information provided.

Antibody Data

Product number

DCABH-3230

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-3230, RRID:AB_2477096

Product name

Rabbit Anti-Human Bcl10 monoclonal antibody, clone TO85-15

Antibody type

Monoclonal

Description

Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NF°ÙB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation