BCL10

gene product
c-E10, CARMEN, CIPER, CLAP, mE10
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1244 antibodies from 43 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
436 antibodies
Novus Biologicals
81 antibodies
GeneTex
13 antibodies
Invitrogen Antibodies
16 antibodies
OriGene
178 antibodies
Biorbyt
42 antibodies
Acris Antibodies GmbH
28 antibodies
Abgent
10 antibodies
Proteintech Group
3 antibodies
NovoPro Bioscience Inc.
8 antibodies
NSJ Bioreagents
7 antibodies
Abnova Corporation
16 antibodies
St John's Laboratory
4 antibodies
Boster Biological Technology
5 antibodies
LifeSpan BioSciences, Inc.
145 antibodies
Bioworld Technology, Inc
1 antibody
Aviva Systems Biology
8 antibodies
Affinity Biosciences
3 antibodies
R&D Systems
2 antibodies
Atlas Antibodies
1 antibody
Enzo Life Sciences
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
ProSci
3 antibodies
RabMAbs
9 antibodies
Bethyl Laboratories
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
54 antibodies
Creative Biolabs
43 antibodies
MyBioSource
20 antibodies
Creative Diagnostics
13 antibodies
Leading Biology
13 antibodies
EMD Millipore
3 antibodies
Abbiotec
1 antibody
BioLegend
1 antibody
Spring Bioscience
16 antibodies
GenWay
7 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Sigma-Aldrich
4 antibodies
Abbexa
3 antibodies
RayBiotech, Inc.
2 antibodies
Exalpha Biologicals, Inc.
1 antibody