Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN152032 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Breast Cancer 1 (BRCA1) (AA 1314-1864) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1314-1864
- Isotype
- IgG
- Antibody clone number
- MU
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks.
Assessing 'radiosensitivity' with kinetic profiles of γ-H2AX, 53BP1 and BRCA1 foci.
ATM activation by ionizing radiation requires BRCA1-associated BAAT1.
Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization.
Martin NT, Nakamura K, Paila U, Woo J, Brown C, Wright JA, Teraoka SN, Haghayegh S, McCurdy D, Schneider M, Hu H, Quinlan AR, Gatti RA, Concannon P
Cell death & disease 2014 Mar 20;5:e1130
Cell death & disease 2014 Mar 20;5:e1130
Assessing 'radiosensitivity' with kinetic profiles of γ-H2AX, 53BP1 and BRCA1 foci.
Martin NT, Nahas SA, Tunuguntla R, Fike F, Gatti RA
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011 Oct;101(1):35-8
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011 Oct;101(1):35-8
ATM activation by ionizing radiation requires BRCA1-associated BAAT1.
Aglipay JA, Martin SA, Tawara H, Lee SW, Ouchi T
The Journal of biological chemistry 2006 Apr 7;281(14):9710-8
The Journal of biological chemistry 2006 Apr 7;281(14):9710-8
Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization.
Okada S, Ouchi T
The Journal of biological chemistry 2003 Jan 17;278(3):2015-20
The Journal of biological chemistry 2003 Jan 17;278(3):2015-20
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS