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Western blot
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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [2]
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- Product number
- NB100-226 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-226, RRID:AB_2243739
- Product name
- Rabbit Polyclonal BRCA1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Characterization of the platelet-derived growth factor receptor-α-positive cell lineage during murine late lung development.
Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP).
Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1.
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.
Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.
Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines.
ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis.
Ntokou A, Klein F, Dontireddy D, Becker S, Bellusci S, Richardson WD, Szibor M, Braun T, Morty RE, Seeger W, Voswinckel R, Ahlbrecht K
American journal of physiology. Lung cellular and molecular physiology 2015 Nov 1;309(9):L942-58
American journal of physiology. Lung cellular and molecular physiology 2015 Nov 1;309(9):L942-58
Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP).
Rosen DB, Leung LY, Louie B, Cordeiro JA, Conroy A, Shapira I, Fields SZ, Cesano A, Hawtin RE
Journal of translational medicine 2014 Jun 25;12:184
Journal of translational medicine 2014 Jun 25;12:184
Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1.
Rusin M, Zajkowicz A, Butkiewicz D
Mechanisms of ageing and development 2009 Aug;130(8):528-37
Mechanisms of ageing and development 2009 Aug;130(8):528-37
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.
Cheng WH, Muftic D, Muftuoglu M, Dawut L, Morris C, Helleday T, Shiloh Y, Bohr VA
Molecular biology of the cell 2008 Sep;19(9):3923-33
Molecular biology of the cell 2008 Sep;19(9):3923-33
Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.
Zaugg K, Su YW, Reilly PT, Moolani Y, Cheung CC, Hakem R, Hirao A, Liu Q, Elledge SJ, Mak TW
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 6;104(10):3805-10
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 6;104(10):3805-10
Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines.
Nunnari G, Argyris E, Fang J, Mehlman KE, Pomerantz RJ, Daniel R
Virology 2005 May 10;335(2):177-84
Virology 2005 May 10;335(2):177-84
ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis.
Andersen JL, Zimmerman ES, DeHart JL, Murala S, Ardon O, Blackett J, Chen J, Planelles V
Cell death and differentiation 2005 Apr;12(4):326-34
Cell death and differentiation 2005 Apr;12(4):326-34
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BRCA1 [p Ser1423] Antibody [NB100-226] - Detection of Brca1 phospho Ser 1423 by Western blot using NB 100-226. Sample whole cell lysate (25 mcg/lane) from HeLa cells treated with 10 Gy IR or untreated. NB 100-226 was used at 1:2500 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BRCA1 [p Ser1423] Antibody [NB100-226] - Detection of Human Phospho BRCA1 (S1423) by Western Blot. Samples : Whole cell lysate (50 ug) from HeLa cells treated with 100 uM EPE for 4 hours (+) or mock treated (-) cells. Antibody: Affinity purified rabbit anti-Phospho BRCA1 (S1423) antibody NB100-226 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
